Results 91 to 100 of about 119,167 (203)
Toxins, 2015 Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Carolina Gay +3 more
doaj +1 more source
Predicting antibacterial activity from snake venom proteomes
PLOS ONE, 2020 The continued evolution of antibiotic resistance has increased the urgency for new antibiotic development, leading to exploration of non-traditional sources. In particular, snake venom has garnered attention for its potent antibacterial properties. Numerous studies describing snake venom proteomic composition as well as antibiotic efficacy have created
Justin L. Rheubert +4 more
openaire +4 more sources
Advanced Science, Volume 13, Issue 45, 13 August 2026.This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan +10 more
wiley +1 more source
Kinome scale profiling of venom effects on cancer cells reveals potential new venom activities [PDF]
, 2020 The search for novel and relevant cancer therapeutics is continuous and ongoing. Cancer adaptations, resulting in therapeutic treatment failures, fuel this continuous necessity for new drugs to novel targets.
Knight, E. +4 more
core +1 more source
Biomolecules, 2020 Scorpion venoms are a rich source of bioactive molecules, but characterisation of toxin peptides affecting cytosolic Ca2+, central to cell signalling and cell death, is limited.
David M. Housley +8 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.This work highlights the satisfactory pharmacokinetic profile of two benzenesulfonylpiperazine lead candidates, followed by in vivo assessment in a murine model of visceral leishmaniasis. This assessment identified compound 2 as moderately active at a lower dose, but its efficacy increased at higher doses, though with concerns regarding safety.
Thibault Joseph William Jacques Dit Lapierre +13 more
wiley +1 more source
Proteomic Deep Mining the Venom of the Red-Headed Krait, Bungarus flaviceps
Toxins, 2018 The use of -omics technologies allows for the characterization of snake venom composition at a fast rate and at high levels of detail. In the present study, we investigated the protein content of Red-headed Krait (Bungarus flaviceps) venom. This analysis
Alex Chapeaurouge +7 more
doaj +1 more source
Engineering Antivenom: Research Progress and Future Directions in Snakebite Envenoming Therapy
Annals of the New York Academy of Sciences, Volume 1562, Issue 1, August 2026.Snakebite envenoming therapy is evolving from plasma‐derived antivenoms toward rationally engineered therapeutics. Advances in toxicovenomics, structural biology, antibody engineering, computational protein design, recombinant expression, small‐molecule inhibitors, and diagnostics are enabling toxin‐centric development of safer, more effective, and ...
Andreas H. Laustsen
wiley +1 more source
Neuromuscular activity of bothrops fonsecai snake venom in vertebrate preparations [PDF]
, 2015 CAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ – CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOThe neuromuscular activity of venom from Bothrops fonsecai, a lancehead endemic to southeastern Brazil, was ...
Hyslop, Stephen +9 more
core
, 2010 The study reported here is a classical bottom-up proteomic approach where proteins from wasp venom were extracted and separated by 2-DE; the individual protein spots were proteolytically digested and subsequently identified by using tandem mass ...
Fabio Morato Castro +31 more
core +1 more source