Results 41 to 50 of about 2,427 (259)
Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, [PDF]
, 2013 Background Understanding the processes that drive the evolution of snake venom is a topic of great research interest in molecular and evolutionary toxinology. Recent studies suggest that ontogenetic changes in venom composition are genetically controlled
Angulo, Yamileth +10 more
core +2 more sources
Toxins, 2015 Venomics is a modern approach that combines transcriptomics and proteomics to explore the toxin content of venoms. This review will give an overview of computational approaches that have been created to classify and consolidate venomics data, as well as ...
Quentin Kaas, David J. Craik
doaj +1 more source
Analytical methods for honeybee venom characterization
Journal of Advanced Pharmaceutical Technology & Research, 2022 The discovery of new drugs has benefited significantly from the development of research in venomics, increasing our understanding of the envenomation processes.
Iouraouine El Mehdi +5 more
doaj +1 more source
Purification of a fragment obtained by autolysis of a PIIIb-SVMP from Bothrops alternatus venom [PDF]
, 2018 Snake Venom Metalloproteinases (SVMPs) represent 43.1% of the components in Bothrops alternatus venom and play an important role in envenomation. Disintegrins and disintegrin-like domains are released by proteolytic processing of PII and PIII classes of ...
Acosta, Ofelia Cristina +9 more
core +1 more source
Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms
Toxins, 2014 Snakebite envenoming represents a neglected tropical disease that has a heavy public health impact worldwide, mostly affecting poor people involved in agricultural activities in Africa, Asia, Latin America and Oceania.
Juan J. Calvete +4 more
doaj +1 more source
Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach
Marine Drugs, 2021 Animal venoms offer a valuable source of potent new drug leads, but their mechanisms of action are largely unknown. We therefore developed a novel network pharmacology approach based on multi-omics functional data integration to predict how stingray ...
Kim N. Kirchhoff +5 more
doaj +1 more source
Identifying Intraspecific Variation in Venom Yield of Chinese Cobra (Naja atra) from Ten Populations in Mainland China [PDF]
, 2019 Detailed information on venom yield is helpful in preparing antivenoms and treating snakebites, but such information is lacking for many species of venomous snakes.
Hongliang LU +6 more
core +1 more source
Toxins, 2021 Meteorus pulchricornis (Ichneumonoidea, Braconidae) is an endoparasitoid wasp of lepidopteran caterpillars. Its parasitic success relies on vesicles (named M.
Jean-Luc Gatti +10 more
doaj +1 more source
Tropical Medicine and Infectious Disease, 2018 The venom proteome of Siamese Russell’s viper from Taiwan, alongside complementary in vivo lethality neutralization assay and in vitro third-generation antivenomics assessment of the preclinical efficacy of the homologous antivenom manufactured in ...
Libia Sanz +5 more
doaj +1 more source
, 2017 Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J +5 more
core +3 more sources