Results 11 to 20 of about 5,048,560 (285)

Ventilator associated or induced lung injury. Does the name matter? Point and counterpoint

Journal of Mechanical Ventilation
The terminology used to describe lung injuries in patients receiving mechanical ventilation has significant implications for clinical practice, research, and communication among healthcare professionals.
Aurio Fajardo-Campoverdi, Ehab G. Daoud
doaj   +2 more sources

Extracellular matrix remodeling modifies structural responses to ventilator-induced lung injury: a multiscale correlative imaging study [PDF]

Respiratory Research
Background Mechanical ventilation (MV) can induce or exacerbate ventilator-induced lung injury (VILI), particularly in mechanically heterogeneous lungs with pre-existing injury. Methods We investigated VILI in a rat model of bleomycin-induced lung injury
Md Motiur Rahman Sagar, Lorenzo D’Amico, Richard T. Deyhle, Ruth Meyer, Luca Fardin, Irma Mahmutovic Persson, Jose Luis Cercos-Pita, Gaetano Perchiazzi, Sarah Köster, Claudia V. Benke, Frauke Alves, Giuliana Tromba, Lars E. Olsson, Sam Bayat, Christian Dullin   +14 more
doaj   +2 more sources

Antenatal Vitamin A Decreases Ventilation-induced Lung Injury in the Lamb Model of Congenital Diaphragmatic Hernia [PDF]

Asian Journal of Surgery, 2006
Infants with congenital diaphragmatic hernia (CDH) are susceptible to ventilation-induced lung injury. Vitamin A may protect the lung from injury during ventilation.
Nicola A. Lewis, Bruce A. Holm, Daniel Swartz, June Sokolowski, Jon Rossman, Philip L. Glick   +5 more
doaj   +2 more sources

A Biofabricated Human Acinus-on-a-Chip Unveils Mechanotransductive Drivers of Ventilator-Induced Lung Injury via Decoupling Volutrauma and Barotrauma. [PDF]

Adv Sci (Weinh)
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Lu H, Liu L, Hu Z, Fang S, Ren R, Liu S, Zhao M, Luo Z, Zhang Z, Shao W, Liu Q.   +10 more
europepmc   +2 more sources

Mechanical ventilation activates PERK/eIF2α and NOD1 pathways that contribute to NF-κB–driven inflammation in VILI [PDF]

Respiratory Research
Background Ventilator-induced lung injury (VILI) is characterized by acute lung damage and NF-κB–driven cytokine production during mechanical ventilation.
Maoyao Ling, Yalan Jiang, Umut Cakir, Kejian Lu, Xiaoting Liao, Guiting Yang, Liu Ji, Tingting Meng, Cuiyuan Huang, Liu Ye, Linghui Pan   +10 more
doaj   +2 more sources

Hidden Microatelectases Increase Vulnerability to Ventilation-Induced Lung Injury. [PDF]

Front Physiol, 2020
Albert K, Krischer JM, Pfaffenroth A, Wilde S, Lopez-Rodriguez E, Braun A, Smith BJ, Knudsen L.   +7 more
europepmc   +2 more sources

Fresh and Cryopreserved Human Umbilical-Cord-Derived Mesenchymal Stromal Cells Attenuate Injury and Enhance Resolution and Repair following Ventilation-Induced Lung Injury. [PDF]

Int J Mol Sci, 2021
Horie S, Gonzalez H, Brady J, Devaney J, Scully M, O'Toole D, Laffey JG.   +6 more
europepmc   +2 more sources

Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway. [PDF]

Front Pharmacol
Liu G, Dong BB, Ding ZH, Lan C, Zhu CJ, Liu Q.   +5 more
europepmc   +2 more sources

Na,K-ATPase Gene Transfer Increases Liquid Clearance during Ventilation-induced Lung Injury

American Journal of Respiratory and Critical Care Medicine, 2003
Karen Ridge, Jacob Sznajder, Phillip Factor   +2 more
exaly   +2 more sources

The Role of Cyclooxygenase-2 in Mechanical Ventilation–Induced Lung Injury

American Journal of Respiratory Cell and Molecular Biology, 2012
Jeffrey A Gold
exaly   +2 more sources