Results 11 to 20 of about 66,463 (247)

Opiates and Plasticity in the Ventral Tegmental Area [PDF]

ACS Chemical Neuroscience, 2017
Opioids are among the most effective pain relievers; however, their abuse has been on the rise worldwide evident from an alarming increase in accidental opioid overdoses. This demands for an urgent increase in scientific endeavors for better understanding of main cellular mechanisms and circuits involved in opiate addiction.
Ludovic D. Langlois, Fereshteh S. Nugent
openaire   +2 more sources

Multiple Personalities in the Ventral Tegmental Area [PDF]

Neuron, 2011
A small number of ventral tegmental area dopamine neurons engage in numerous and apparently contradictory functions--how can this be? A clue is provided by Lammel and colleagues in this issue of Neuron: some VTA dopamine neurons display synaptic plasticity in response to cocaine, and others in response to pain, and these populations are distinguished ...
Borgkvist, Anders, Mrejeru, Ana, Sulzer, David   +2 more
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Functional neuroanatomical review of the ventral tegmental area [PDF]

NeuroImage, 2019
The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are assumed to play a key role in dopamine-related functions such as reward-related behaviour, motivation, addiction and motor functioning. Although dopamine-producing midbrain structures are bordering, they show significant differences in structure and function that argue for a ...
Anne C. Trutti, Martijn J. Mulder, Bernhard Hommel, Birte U. Forstmann   +3 more
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Glutamatergic Afferents of the Ventral Tegmental Area in the Rat [PDF]

The Journal of Neuroscience, 2007
Glutamatergic inputs to the ventral tegmental area (VTA), thought crucial to the capacity of the VTA to detect and signal stimulus salience, have been reported to arise in but a few structures. However, the afferent system of the VTA comprises very abundant neurons within a large formation extending from the prefrontal cortex to ...
Stefanie, Geisler, Christian, Derst, Rüdiger W, Veh, Daniel S, Zahm   +3 more
openaire   +2 more sources

Visual and Electrosensory Circuits of the Diencephalon in Mormyrids [PDF]

, 1990
Mormyrids are one of two groups of teleost fishes known to have evolved electroreception, and the concomitant neuroanatomical changes have confounded the interpretation of many of their brain areas in a comparative context, e.g., the diencephalon, where ...
Adams, Bell, Bell, Bell, Bell, Bell, Bell, Bergquist, Braford, Bullock, Bullock, Carr, Ebbesson, Ebbesson, Echteler, Echteler, Erdl, Fiebig, Finger, Franz, Franz, Franz, Grover, Hanker, Harder, Haugede-Carre, Haugede-Carre, Holmgren, Hopkins, Hopkins, Ito, Ito, Ito, Ito, Keller, Keller, Lauder, Lazar, Luiten, Maler, Maler, McCormick, Meek, Meek, Meek, Murakami, Murakami, Murakami, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Northcutt, Northcutt, Northcutt, Northcutt, Sas, Sheldon, Stendell, Stendell, Stendell, Striedter, Striedter, Striedter, Suzuki, Szabo, van der Sprenkel, Weston, Wullimann, Wullimann, Wullimann, Wullimann   +71 more
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Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine [PDF]

, 2013
Nicotine exerts its reinforcing action by stimulating nicotinic acetylcholine receptors (nAChRs) and boosting dopamine (DA) output from the ventral tegmental area (VTA).
A Taly, AA Grace, AJ Yu, AO Komendantov, AR Tapper, B Buisson, B Katz, Boris Gutkin, C Lüscher, C Shelley, CP Fenster, DB Carr, E Lichtenstein, E Sher, EJ Nestler, F Marti, FE Pontieri, G Di Chiara, G Di Chiara, G Di Chiara, GL Forster, HD Mansvelder, HD Mansvelder, HR Wilson, IW Jones, J Cornwall, J Grenhoff, JA Dani, Ja Dani, JB Eaton, JE Henningfield, JE Rose, JN Reynolds, JP Changeux, JP Changeux, JP Changeux, JR Clements, JR Wooltorton, K Chergui, Karl J. Friston, KG Paradiso, LE Chavez-Noriega, M Gao, M Garzón, M Graupner, M Mameli-Engvall, M Wu, MG Lacey, Michael Graupner, MJ Christie, MR Picciotto, MR Picciotto, N Champtiaux, P Dayan, PW Kalivas, R Exley, R Giniatullin, R Klink, R Nashmi, Reinoud Maex, RL Papke, S Erhardt, S Ikemoto, S Tolu, SA Oakman, SC Steffensen, SR Grady, SR Sesack, SW Johnson, SW Johnson, TC Jhou, V David, V Gerzanich, V Gerzanich, VI Pidoplichko, WA Corrigall, X Peng, ZM Fagen, ZY Tong   +78 more
core   +6 more sources

Learning Contextual Reward Expectations for Value Adaptation [PDF]

, 2018
Substantial evidence indicates that subjective value is adapted to the statistics of reward expected within a given temporal context. However, how these contextual expectations are learned is poorly understood.
Chew, B., Dayan, P., Dolan, R.J., Rigoli, F.   +3 more
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Anticipatory pleasure predicts effective connectivity in the mesolimbic system

Frontiers in Behavioral Neuroscience, 2015
Convergent evidence suggests the important role of the mesolimbic pathway in anticipating monetary rewards. However, the underlying mechanism of how the sub-regions interact with each other is still not clearly understood.
Zhi eLi, Zhi eLi, Chao eYan, Wei-zhen eXie, Ke eLi, Ya-wei eZeng, Zhen eJin, Eric F. C. Cheung, Raymond C. K. Chan   +8 more
doaj   +1 more source

Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections

Nature Communications, 2021
The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.
Darshini Mahadevia, Rinki Saha, Alessia Manganaro, Nao Chuhma, Annette Ziolkowski-Blake, Ashlea A. Morgan, Dani Dumitriu, Stephen Rayport, Mark S. Ansorge   +8 more
doaj   +1 more source

Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition. [PDF]

, 2018
Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that ...
Carter, Cameron S, Minzenberg, Michael J, Soosman, Steffan K, Yoon, Jong H   +3 more
core   +3 more sources