Linking actions to outcomes : the role of the posterior pedunculopontine tegmental nucleus in instrumental learning [PDF]
, 2012 Located in the mesopontine tegmentum, the pedunculopontine tegmental nucleus (PPTg) is comprised principally of glutamatergic, cholinergic and GABAergic neurons.
MacLaren, Duncan A. A.
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Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking [PDF]
, 2014 The authors show that rostral ventral pallidum projections to the ventral tegmental area (VTA) are activated during cue-induced reinstatement of cocaine seeking, and DREADD inhibition of these projections blocks this behavior.
Karl Deisseroth +19 more
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Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulationin vitro [PDF]
The Journal of Physiology, 2009 Anatomical studies indicate that synaptic inputs from many cortical and subcortical structures converge on neurons of the ventral tegmental area (VTA). Althoughin vitroelectrophysiological studies have examined synaptic inputs to dopamine (DA) and non‐DA neurons in the VTA, they have largely relied upon local electrical stimulation to activate these ...
Cameron H, Good, Carl R, Lupica
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Prompting social investigation
eLifeA social memory pathway connecting the ventral hippocampus, the lateral septum and the ventral tegmental area helps to regulate how mice react to unknown individuals.
Emma Keppler, Susanna Molas
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Opioid Modulation of Ventral Pallidal Afferents to Ventral Tegmental Area Neurons [PDF]
The Journal of Neuroscience, 2013 Activation of mu opioid receptors within the ventral tegmental area (VTA) can produce reward through the inhibition of GABAergic inputs. GABAergic neurons in the ventral pallidum (VP) provide a major input to VTA neurons. To determine the specific VTA neuronal targets of VP afferents and their sensitivity to mu opioid receptor agonists, we virally ...
Hjelmstad, Gregory O +3 more
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The Effect of L-arginine in the Ventral Tegmenta Area on the Improving Effect of Nicotine on Memory
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012 Background and Objectives: Nitric oxide synthesis has been detected in ventral tegmental area, which is a key brain region that seems to mediate behavioral effect of morphine and nicotine.
MS Shahin, M Piri, MR Zarrindast
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Nature CommunicationsThe potential brain mechanism underlying resilience to socially transferred allodynia remains unknown. Here, we utilize a well-established socially transferred allodynia paradigm to segregate male mice into pain-susceptible and pain-resilient subgroups ...
Yi Han +19 more
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Ventral tegmental area subcircuits process rewarding and aversive experiences
, 2016 The ventral tegmental area is a heterogeneous brain structure that plays a central role in rewarding and aversive experience processing. Studies suggest that several subpopulations within the ventral tegmental area form subcircuits that are ...
Bariselli, Sebastiano +11 more
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Ventral tegmental area astrocytes orchestrate avoidance and approach behavior
Nature Communications, 2019 Astrocytes can dynamically control glutamate availability at specific active synapses through the glutamate transporter, GLT-1. Here, the authors show that astrocytes in the VTA selectively facilitate excitation of VTA GABAergic neurons to inhibit ...
J. A. Gomez +12 more
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Molecular implications of prolonged aggression experience: Th, Dat1, Snca and Bdnf gene expression in the ventral tegmental area of the victorious male mice [PDF]
, 2008 Th, Dat1, Snca and Bdnf were the genes whose mRNA levels in the ventral tegmental area of the midbrain were measured in male mice that were victorious in 20 daily agonistic interactions and in a group of such victorious mice that had later not been ...
I. L. Kovalenko +9 more
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