Results 41 to 50 of about 6,470,327 (195)

Circadian regulation of hedonic appetite in mice by clocks in dopaminergic neurons of the VTA

Nature Communications, 2020
In addition to promoting overconsumption, palatable diets dampen daily intake patterns, which further augments metabolic dysfunction. Here, the authors find that in mice, circadian clocks in dopaminergic neurons in the ventral tegmental area drive ...
C. E. Koch, K. Begemann, J. T. Kiehn, L. Griewahn, J. Mauer, M. E. Hess, A. Moser, S. M. Schmid, J. C. Brüning, H. Oster   +9 more
doaj   +1 more source

TPH2 in the ventral tegmental area of the male rat brain [PDF]

Brain Research Bulletin, 2011
This study surveyed the distribution of tryptophan hydroxylase 2 (TPH2) mRNA, protein, and enzymatic activity throughout the male Sprague-Dawley rat brain. TPH2 is the genetic isoform of TPH that catalyzes the rate-limiting step in serotonin biosynthesis within the central nervous system.
Nurgul, Carkaci-Salli, Ugur, Salli, Kara L, Kuntz-Melcavage, Michael M, Pennock, Hande, Ozgen, Izel, Tekin, Willard M, Freeman, Kent E, Vrana   +7 more
openaire   +2 more sources

Determination of circuit-specific morphological adaptations in ventral tegmental area dopamine neurons by chronic morphine

Molecular Brain, 2019
Chronic opiate exposure induces neuroadaptations in the mesocorticolimbic system including ventral tegmental area (VTA) dopamine (DA) neurons, whose soma size is decreased following opiate exposure.
Sarah C. Simmons, Katie Wheeler, Michelle S. Mazei-Robison   +2 more
doaj   +1 more source

Top gene ontology enrichment results for ventral tegmental area mega module bisque.

, 2019
Top gene ontology enrichment results for ventral tegmental area mega module bisque.
Silviu A. Bacanu (6631004), Kristin M. Mignogna (6631001), Brien P. Riley (189920), Aaron R. Wolen (173040), Michael F. Miles (173062)   +4 more
core   +1 more source

Aversion or Salience Signaling by Ventral Tegmental Area Glutamate Neurons

iScience, 2018
Summary: Ventral tegmental area (VTA) neurons play roles in reward and aversion. The VTA has, in addition to dopamine neurons, glutamatergic neurons expressing VGluT2.
David H. Root, David J. Estrin, Marisela Morales   +2 more
doaj   +1 more source

Glutamatergic and dopaminergic neurons in the mouse ventral tegmental area [PDF]

European Journal of Neuroscience, 2015
Abstract The ventral tegmental area ( VTA ) comprises dopamine ( DA ), γ‐aminobutyric acid ( GABA ) and glutamate (Glu) neurons.
Tsuyoshi, Yamaguchi, Jia, Qi, Hui-Ling, Wang, Shiliang, Zhang, Marisela, Morales   +4 more
openaire   +2 more sources

Erk1/2 mediates leptin receptor signaling in the ventral tegmental area. [PDF]

PLoS ONE, 2011
Leptin acts on the ventral tegmental area (VTA) to modulate neuronal function and feeding behavior in rats and mice. To identify the intracellular effectors of the leptin receptor (Lepr), downstream signal transduction events were assessed for regulation
Richard Trinko, Geliang Gan, Xiao-Bing Gao, Robert M Sears, Douglas J Guarnieri, Ralph J DiLeone   +5 more
doaj   +1 more source

Lateral preoptic area glutamate neurons relay nociceptive information to the ventral tegmental area

Cell Reports, 2023
Summary: The ventral tegmental area (VTA) has been proposed to play a role in pain, but the brain structures modulating VTA activity in response to nociceptive stimuli remain unclear.
David J. Barker, Shiliang Zhang, Huiling Wang, David J. Estrin, Jorge Miranda-Barrientos, Bing Liu, Rucha J. Kulkarni, Junia Lara de Deus, Marisela Morales   +8 more
doaj   +1 more source

Glutamatergic neurons are present in the rat ventral tegmental area [PDF]

European Journal of Neuroscience, 2007
Abstract The ventral tegmental area (VTA) is thought to play an important role in reward function. Two populations of neurons, containing either dopamine (DA) or γ‐amino butyric acid (GABA), have been extensively characterized in this area.
Tsuyoshi, Yamaguchi, Whitney, Sheen, Marisela, Morales   +2 more
openaire   +2 more sources

Ventral tegmental area mega module bisque.

, 2019
Ventral Tegmental Area Mega Modules Bisque. Solid black arrows point to ALSPAC GWAS nominal genes, and dotted black arrows represent IASPSAD nominal genes. Edge-width is proportional to the difference in correlation strength between treatment and control
Silviu A. Bacanu (6631004), Kristin M. Mignogna (6631001), Brien P. Riley (189920), Aaron R. Wolen (173040), Michael F. Miles (173062)   +4 more
core   +1 more source