Results 41 to 50 of about 66,463 (247)

Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulationin vitro [PDF]

The Journal of Physiology, 2009
Anatomical studies indicate that synaptic inputs from many cortical and subcortical structures converge on neurons of the ventral tegmental area (VTA). Althoughin vitroelectrophysiological studies have examined synaptic inputs to dopamine (DA) and non‐DA neurons in the VTA, they have largely relied upon local electrical stimulation to activate these ...
Cameron H, Good, Carl R, Lupica
openaire   +2 more sources

Opioid Modulation of Ventral Pallidal Afferents to Ventral Tegmental Area Neurons [PDF]

The Journal of Neuroscience, 2013
Activation of mu opioid receptors within the ventral tegmental area (VTA) can produce reward through the inhibition of GABAergic inputs. GABAergic neurons in the ventral pallidum (VP) provide a major input to VTA neurons. To determine the specific VTA neuronal targets of VP afferents and their sensitivity to mu opioid receptor agonists, we virally ...
Hjelmstad, Gregory O, Xia, Yanfang, Margolis, Elyssa B, Fields, Howard L   +3 more
openaire   +5 more sources

Prompting social investigation

eLife
A social memory pathway connecting the ventral hippocampus, the lateral septum and the ventral tegmental area helps to regulate how mice react to unknown individuals.
Emma Keppler, Susanna Molas
doaj   +1 more source

Afferent connections of the valvula cerebelli in two teleosts, the common goldfish and the green sunfish [PDF]

, 1989
The afferent connections of the valvula cerebelli were examined in one cypriniform teleost (Carassius auratus) and one perciform teleost (Lepomis cyanellus) with the use of horseradish peroxidase as a retrograde tracer.
Bell, Braford, Braford, Bullock, Carr, Crispino, Fiebig, Finger, Finger, Finger, Finger, Finger, Gould, Hanker, Hornby, Jakubowski, Kotchabhakdi, Larsell, Lauder, Lee, Mesulam, Murakami, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Northcutt, Northcutt, Northcutt, Northcutt, Parent, Puzdrowski, Puzdrowski, Russell, Sibbing, Szabo, Tong, Tong, Tong, Tong, Wullimann, Wullimann, Wullimann   +43 more
core   +1 more source

The Effect of L-arginine in the Ventral Tegmenta Area on the Improving Effect of Nicotine on Memory

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
Background and Objectives: Nitric oxide synthesis has been detected in ventral tegmental area, which is a key brain region that seems to mediate behavioral effect of morphine and nicotine.
MS Shahin, M Piri, MR Zarrindast
doaj   +2 more sources

Midbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male mice

Nature Communications
The potential brain mechanism underlying resilience to socially transferred allodynia remains unknown. Here, we utilize a well-established socially transferred allodynia paradigm to segregate male mice into pain-susceptible and pain-resilient subgroups ...
Yi Han, Lin Ai, Lingzhen Song, Yu Zhou, Dandan Chen, Sha Sha, Ran Ji, Qize Li, Qingyang Bu, Xiangyu Pan, Xiaojing Zhai, Mengqiao Cui, Jiawen Duan, Junxia Yang, Dipesh Chaudhury, Ankang Hu, He Liu, Ming-Hu Han, Jun-Li Cao, Hongxing Zhang   +19 more
doaj   +1 more source

Ventral tegmental area GABA neurons mediate stress-induced blunted reward-seeking in mice

Nature Communications, 2021
Acute stress transiently disrupts reward-seeking behaviour and repeated stress exposure produces lasting anhedonia-like behaviour in rodents. Here, the authors show that stress triggers GABAergic activity in the ventral tegmental area which blunts reward-
Daniel C. Lowes, Linda A. Chamberlin, Lisa N. Kretsge, Emma S. Holt, Atheir I. Abbas, Alan J. Park, Lyubov Yusufova, Zachary H. Bretton, Ayesha Firdous, Armen G. Enikolopov, Joshua A. Gordon, Alexander Z. Harris   +11 more
doaj   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Ventral tegmental area astrocytes orchestrate avoidance and approach behavior

Nature Communications, 2019
Astrocytes can dynamically control glutamate availability at specific active synapses through the glutamate transporter, GLT-1. Here, the authors show that astrocytes in the VTA selectively facilitate excitation of VTA GABAergic neurons to inhibit ...
J. A. Gomez, J. M. Perkins, G. M. Beaudoin, N. B. Cook, S. A. Quraishi, E. A. Szoeke, K. Thangamani, C. W. Tschumi, M. J. Wanat, A. M. Maroof, M. J. Beckstead, P. A. Rosenberg, C. A. Paladini   +12 more
doaj   +1 more source

Neural correlates of emotion processing comparing antidepressants and exogenous oxytocin in postpartum depressed women: An exploratory study [PDF]

, 2019
Despite common use of antidepressants to treat postpartum depression, little is known about the impact of antidepressant use on postpartum brain activity.
Cheng, Hu, Heiman, Julia R., Lorenz, Tierney K.   +2 more
core   +3 more sources