Results 51 to 60 of about 6,470,327 (195)
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. [PDF]
PLoS ONE, 2010 Nicotine from smoking tobacco produces one of the most common forms of addictive behavior and has major societal and health consequences. It is known that nicotine triggers tobacco addiction by activating nicotine acetylcholine receptors (nAChRs) in the ...
Lei Phillip Wang +3 more
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Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area [PDF]
Cerebral Cortex, 2015 Growing evidence indicates that midbrain dopamine (DA) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute errors in reward prediction. Here we investigated how 2 major prefrontal subregions, the orbitofrontal cortex (OFC) and the medial prefrontal cortex (mPFC), contributed to DAergic prediction errors ...
Yong Sang, Jo, Sheri J Y, Mizumori
openaire +2 more sources
Is there a way to curb benzodiazepine addiction?
Swiss Medical Weekly, 2011 Benzodiazepines are widely prescribed drugs used to treat anxiety and insomnia, induce muscle relaxation, control epileptic seizures, promote anaesthesia or produce amnesia. Benzodiazepines are also abused for recreational purposes and the number of
AL Lalive, U Rudolph, C Lüscher, KR Tan
doaj +1 more source
Linking Context with Reward: A Functional Circuit from Hippocampal CA3 to Ventral Tegmental Area
, 2011 A hippocampus–to–ventral tegmental area pathway regulates dopamine neurons and is necessary for reinstatement of context-induced cocaine-seeking.
Alice H. Luo +4 more
core +1 more source
مجله دانشکده پزشکی اصفهان, 2020 Background: One of the problems of addiction treatment is the relapsing of withdrawal syndrome signs in the addicted person. Rewarding brain regions such as medial prefrontal cortex (mPFC) and ventral tegmental area (VTA) are involved in addiction and ...
Asal Keramatian +3 more
doaj +1 more source
, 2005 Concurrent use of ethanol and nicotine (tobacco) is often seen in human beings. In previous animal experiments, we have demonstrated that nicotinic acetylcholine receptors, especially α-conotoxin MII and mecamylamine sensitive receptors located in the ...
Engel, Jörgen A., +4 more
core +2 more sources
Acta Neurobiologiae Experimentalis, 1999 Unilateral lesions of the ventral tegmental area (VTA) facilitate behavioral responses (feeding and exploration) induced by electrical stimulation of the VTA in the contralateral hemisphere. It was hypothesized that this facilitation may result from a lesion-induced compensatory increase in dopamine transmission in the intact hemisphere. In the present
M, Maliszewska-Scisło, W, Trojniar
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Glutamatergic Plasticity in Medial Prefrontal Cortex and Ventral Tegmental Area Following Extended-Access Cocaine Self-Administration [PDF]
, 2011 Glutamate signaling in prefrontal cortex and ventral tegmental area plays an important role in the molecular and behavioral plasticity associated with addiction to drugs of abuse.
John R. Mantsch +11 more
core +1 more source
Biological Psychiatry Global Open ScienceBackground: Psychiatric disorders often emerge during late adolescence/early adulthood, a period with increased susceptibility to socioenvironmental factors that coincides with incomplete parvalbumin interneuron (PVI) development.
Débora A.E. Colodete +3 more
doaj +1 more source
Orexinergic input to dopaminergic neurons of the human ventral tegmental area. [PDF]
PLoS ONE, 2013 The mesolimbic reward pathway arising from dopaminergic (DA) neurons of the ventral tegmental area (VTA) has been strongly implicated in reward processing and drug abuse.
Erik Hrabovszky +5 more
doaj +1 more source