Results 71 to 80 of about 66,463 (247)

Modelling the Effect of Dorsal Raphe Serotonin Neurons on Patience for Future Rewards [PDF]

open access: yes, 2016
Serotonin is a neurotransmitter that is implicated in many basic human functions and behaviours and is closely associated with happiness, depression and reward processing.
Porr, Bernd, Sutherland, Marc
core   +1 more source

“Hands‐On” white matter anatomy: Using Air Anatomy gestures and tractography on simple brain sections to enhance teaching of white matter directions

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan   +7 more
wiley   +1 more source

Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. [PDF]

open access: yesPLoS ONE, 2010
Nicotine from smoking tobacco produces one of the most common forms of addictive behavior and has major societal and health consequences. It is known that nicotine triggers tobacco addiction by activating nicotine acetylcholine receptors (nAChRs) in the ...
Lei Phillip Wang   +3 more
doaj   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

open access: yes, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Benigno, Arcangelo   +6 more
core   +1 more source

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

open access: yes, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC   +5 more
core   +2 more sources

Gating of social reward by oxytocin in the ventral tegmental area [PDF]

open access: yesScience, 2017
Brain circuits that modulate sociability Understanding the neural mechanisms that mediate social reward has important societal and clinical implications. Hung et al. found that release of the neuropeptide oxytocin in the ventral tegmental area of the brain increased prosocial behaviors in mice (see the ...
Lin W. Hung   +10 more
openaire   +2 more sources

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

open access: yesAutism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni   +6 more
wiley   +1 more source

Is there a way to curb benzodiazepine addiction?

open access: yesSwiss Medical Weekly, 2011
Benzodiazepines are widely prescribed drugs used to treat anxiety and insomnia, induce muscle relaxation, control epileptic seizures, promote anaesthesia or produce amnesia. Benzodiazepines are also abused for recreational purposes and the number of
AL Lalive, U Rudolph, C Lüscher, KR Tan
doaj   +1 more source

Role of the Primate Ventral Tegmental Area in Reinforcement and Motivation [PDF]

open access: yesCurrent Biology, 2014
Monkey electrophysiology suggests that the activity of the ventral tegmental area (VTA) helps regulate reinforcement learning and motivated behavior, in part by broadcasting prediction error signals throughout the reward system. However, electrophysiological studies do not allow causal inferences regarding the activity of VTA neurons with respect to ...
Arsenault JT   +3 more
openaire   +3 more sources

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins   +23 more
wiley   +1 more source

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