Results 61 to 70 of about 6,470,327 (195)

Central mechanisms of taste: Cognition, emotion and taste-elicited behaviors

Japanese Dental Science Review, 2008
Taste is unique among sensory systems in its innate association with mechanisms of reward and aversion in addition to its recognition of quality, e.g., sucrose is sweet and preferable, and quinine is bitter and aversive.
Takashi Yamamoto
doaj   +1 more source

Code and additional files for "An atlas of transcriptionally defined cell populations in the rat ventral tegmental area"

, 2022
Zip file containing code and additional files associated with "An atlas of transcriptionally defined cell populations in the rat ventral tegmental area".
Robert A. Phillips III, Jennifer J. Tuscher, Jeremy J. Day, Lara Ianov   +3 more
core   +1 more source

D1 receptors modulate glutamate transmission in the ventral tegmental area

, 1995
Perfusion of the D1 agonist, SKF-82958, through a microdialysis probe implanted in the ventral tegmental area produced a dose-dependent increase in extracellular glutamate and GABA.
P Duffy, PW Kalivas
core   +1 more source

Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons

Nature Communications, 2016
Stress is a major cause of relapse to cocaine seeking behaviour. Tung et al. show that orexin mediates stress-induced reinstatement of cocaine seeking behaviour in mice by endocannabinoid-dependent disinhibition in the ventral tegmental area.
Li-Wei Tung, Guan-Ling Lu, Yen-Hsien Lee, Lung Yu, Hsin-Jung Lee, Emma Leishman, Heather Bradshaw, Ling-Ling Hwang, Ming-Shiu Hung, Ken Mackie, Andreas Zimmer, Lih-Chu Chiou   +11 more
doaj   +1 more source

5-HT2A receptor activation normalizes stress-induced dysregulation of GABAergic signaling in the ventral tegmental area

, 2019
This dataset contains raw data from ex vivo electrophysiological recordings and western blot analysis in support of the manuscript "5-HT2A receptor activation normalizes stress-induced dysregulation of GABAergic signaling in the ventral tegmental area"
Blake Kimmey
core   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian, Zammit C, Di Giovanni, Giuseppe, Muscat, Richard, Pitruzzella A, Muscat R, Pierucci M, Valentino, Mario, Benigno, Arcangelo, Di Giovanni G., Pierucci, Massimo, Valentino M, Pitruzzella, Alessandro   +12 more
core  

Granulocyte-Colony-Stimulating Factor Alters the Proteomic Landscape of the Ventral Tegmental Area

Proteomes, 2018
Cocaine addiction is characterized by aberrant plasticity of the mesolimbic dopamine circuit, leading to dysregulation of motivation to seek and take drug.
Nicholas L. Mervosh, Rashaun Wilson, Navin Rauniyar, Rebecca S. Hofford, Munir Gunes Kutlu, Erin S. Calipari, TuKiet T. Lam, Drew D. Kiraly   +7 more
doaj   +1 more source

Untangling dopamine and glutamate in the ventral tegmental area

ABSTRACT Ventral tegmental area (VTA) dopamine neurons are of great interest for their central roles in motivation, learning, and psychiatric disorders. While hypotheses of VTA dopamine neuron function posit a homogenous role in behavior (e.g., prediction error), they do not account for molecular heterogeneity.
Emily D. Prévost, Lucy A. Ward, Daniel Alas, Giulia Aimale, Sara Ikenberry, Katie Fox, Julianne Pelletier, Annie Ly, Jayson Ball, Zachary P. Kilpatrick, Kailyn Price, Abigail M. Polter, David H. Root   +12 more
openaire   +2 more sources

SARS-CoV-2 propagation to the TPH2-positive neurons in the ventral tegmental area induces cell death via GSK3β-dependent accumulation of phosphorylated tau.

PLoS ONE
COVID-19, an infectious disease caused by SARS-CoV-2, was declared a pandemic by the WHO in 2020. Psychiatric symptoms including sleep disturbance, memory impairment, and depression are associated with SARS-CoV-2 infection. These symptoms are causes long-
Motoki Imai, Fumitaka Kawakami, Takayuki Uematsu, Toshihide Matsumoto, Rei Kawashima, Yoshifumi Kurosaki, Shun Tamaki, Shotaro Maehana, Takafumi Ichikawa, Hideaki Hanaki, Hidero Kitazato, Makoto Kubo   +11 more
doaj   +1 more source

Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors

Nature Communications, 2018
Dopamine neurons in the ventral tegmental area (VTA) are implicated in depressive-like behaviors. Here, the authors show that cholinergic inputs to the VTA from the laterodorsal tegmentum regulate intrinsic plasticity of VTA DA neurons to mediate stress ...
Sebastian P. Fernandez, Loïc Broussot, Fabio Marti, Thomas Contesse, Xavier Mouska, Mariano Soiza-Reilly, Hélène Marie, Philippe Faure, Jacques Barik   +8 more
doaj   +1 more source