Results 11 to 20 of about 78,658 (276)

PROTECTIVE EFFECTS OF VERAPAMIL AGAINST HEXACHLOROBUTADIENE NEPHROTOXICITY IN RATS [PDF]

open access: yesPakistan Veterinary Journal, 2008
In order to evaluate the protective effect of verapamil against hexachlorobutadiene (HCBD) nephrotoxicity, 30 adult Wistar albino rats were divided into five equal groups, A, B, C, D and E and were given intra-peritonially corn oil (I ml/kg; control ...
E. MOGHTADAI KHORASGANI, K. MANOCHEHRI AND M. HOSSEINI1
doaj   +2 more sources

Evaluating the antidiabetic effects of R-verapamil in type 1 and type 2 diabetes mellitus mouse models.

open access: yesPLoS ONE, 2021
The global incidence of diabetes mellitus (DM) is increasing. Types 1 and 2 DM are associated with declining β-cell function. Verapamil (50% S-verapamil and 50% R-verapamil) can treat DM by downregulating thioredoxin-interacting protein (TXNIP), which ...
Yu-Syuan Chen   +8 more
doaj   +2 more sources

Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil

open access: yesPharmaceutical Biology, 2022
Context Solanaceae glycoalkaloids (SGAs) possess cardiomodulatory activity.Objective This study investigated the potential interaction between verapamil and glycoalkaloids.Material and methods The cardioactivity of verapamil and glycoalkaloids (α ...
Szymon Chowański   +9 more
doaj   +1 more source

Verapamil and the myocardium [PDF]

open access: yesPostgraduate Medical Journal, 1974
SummaryAlthough many of the drugs which recently have been developed for use in relieving angina pectoris display β-adrenoceptor blocking activity this property cannot be essential, because verapamil relieves angina pectoris without blocking the cardiac β-adrenoceptors.
Winifred G. Nayler, Dennis M. Krikler
openaire   +3 more sources

Effect of calcium channel blocker on steroid hormone profile of primary cultured aldosterone producing adenoma cells [PDF]

open access: yesJichu yixue yu linchuang, 2022
Objective To explore the influence of calcium channel blocker(CCB), verapamil, on steroid hormone profile of primary cultured aldosterone producing adenoma(APA)cells.
GAO Yin-jie, YU Song-lin, YIN Yi-cong, CUI Yun-ying, ZHANG Yu-shi, QIU Ling, TONG An-li
doaj   +1 more source

Effects of Verapamil on the Reduction of Radial Artery Thrombosis after Coronary Angiography: A Randomized Clinical Trial

open access: yesJournal of Tehran University Heart Center, 2022
Background: The trans-radial approach significantly reduces access bleeding and underlying vascular complications and is associated with lower healthcare costs than the transfemoral approach.
Mohammadreza Beyranvand   +3 more
doaj   +1 more source

Anti-arrhythmic effect of verapamil is accompanied by preservation of cx43 protein in rat heart. [PDF]

open access: yesPLoS ONE, 2013
The present study was to test the hypothesis that anti-arrhythmic properties of verapamil may be accompanied by preserving connexin43 (Cx43) protein via calcium influx inhibition.
Peng Zhou   +5 more
doaj   +1 more source

Effect of verapamil on the pharmacokinetics of hydroxycamptothecin and its potential mechanism

open access: yesPharmaceutical Biology, 2020
Context Hydroxycamptothecin (HCPT) has antitumor activity in various cancers, but its poor bioavailability and efflux limit its clinical application. Verapamil has been demonstrated to improve the bioavailability of many drugs.
Hua Xing   +6 more
doaj   +1 more source

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