Results 51 to 60 of about 10,151 (207)

SOX6 is expressed in various cell lineages in the developing mouse heart and contributes to proper valvuloseptal development

open access: yesThe Anatomical Record, EarlyView.
Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli   +6 more
wiley   +1 more source

Different mRNA and Protein Expression of Versican in TGF-β1-treated Prostate Cancer Cells

open access: yesForbes Tıp Dergisi, 2022
Objective: Cellular heterogeneity of tumors stems from cell populations expressing a unique set of proteins defective genetic and epigenetic networks.
Burak SONER   +5 more
doaj   +1 more source

mRNA expression for versican isoforms in temporomandibular joint discs of growing rats : Analysis using real-time quantitative PCR with the TaqMan prove [PDF]

open access: yes, 2005
P(論文)Versican is a large chondroitin sulphate proteoglycan distributed in a variety of interstitial connective tissue. Versican is thought to be involved in extracellular matrix assembly and various biological cellular interactions.
TAKUMA, Taishin   +19 more
core  

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Versican/Collagen Interactions in Tissue Structure and Mechanics [PDF]

open access: yes, 2021
Type I collagen is the most abundant structural protein in the extracellular matrix (ECM), forming a dynamic 3D fibrous network that is highly regulated by other ECM components including proteoglycans (PGs) and glycosaminoglycans (GAGs).
Chen, Dongning
core  

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery   +4 more
wiley   +1 more source

Context-dependent bioactivity of versican fragments

open access: yesGlycobiology, 2019
AbstractVersican (VCAN) proteolysis and the accumulation of VCAN fragments occur in many developmental and disease processes, affecting extracellular matrix (ECM) structure and cell phenotype. Little is known about the significance of proteolysis and the roles of fragments, or how this ECM remodeling affects the microenvironment and phenotype of ...
Katherine Payne, Timms   +1 more
openaire   +2 more sources

Versican increases smooth muscle α-actin expression.

open access: yes, 2015
(A) Versican induced a 1.38 ± 0.15 fold increase in smooth muscle α-actin mRNA expression ...
Bruce M. McManus (351410)   +6 more
core   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen   +8 more
wiley   +1 more source

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