Results 71 to 80 of about 13,176,453 (293)

Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis

Microbial Cell Factories, 2019
Background Fatty acids (FAs) with a chain length of more than 18 carbon atoms (> C18) are interesting for the production of specialty compounds derived from these FAs. These compounds include free FAs, like erucic acid (C22:1-Δ13), primary fatty alcohols
Leonie Wenning, Christer S. Ejsing, Florian David, Richard R. Sprenger, Jens Nielsen, Verena Siewers   +5 more
doaj   +1 more source

A simple method to isolate fatty acids and fatty alcohols from wax esters in a wax-ester rich marine oil.

PLoS ONE, 2023
Calanus finmarchicus is one of the most important zooplankton species in the North Atlantic. The zooplankton is currently being harvested and industrially processed to a marine oil product for human consumption as a marine nutraceutical containing long ...
Pauke Carlijn Schots, Guro Kristine Edvinsen, Ragnar Ludvig Olsen   +2 more
doaj   +1 more source

Plasmalogens participate in very-long-chain fatty acid-induced pathology [PDF]

Brain, 2008
Peroxisomes are organelles responsible for multiple metabolic pathways including, the biosynthesis of plasmalogens, a class of phospholipids, and the beta-oxidation of very-long-chain fatty acids (VLCFA). Lack of peroxisomes or dysfunction in any of their normal functions is the cellular basis for human peroxisomal disorders.
Brites, Pedro, Mooyer, Petra A. W., El Mrabet, Leila, Waterham, Hans R., Wanders, Ronald J. A.   +4 more
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Impact of fatty acid status on immune function of children in low-income countries.

, 2011
In vitro and animal studies point to numerous mechanisms by which fatty acids, especially long-chain polyunsaturated fatty acids (LCPUFA), can modulate the innate and adaptive arms of the immune system.
Liandré van der Merwe, van der Merwe, Liandré, Prentice, Andrew M, Andrew M. Prentice   +3 more
core   +1 more source

Circulating Very Long‐Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Circulating very‐long‐chain saturated fatty acids (VLSFAs) are integrated biomarkers of diet and metabolism that may point to new risk pathways and potential targets for heart failure (HF) prevention.
Rozenn N. Lemaitre, Barbara McKnight, Nona Sotoodehnia, Amanda M. Fretts, Waqas T. Qureshi, Xiaoling Song, Irena B. King, Colleen M. Sitlani, David S. Siscovick, Bruce M. Psaty, Dariush Mozaffarian   +10 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition. [PDF]

, 2012
Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine.
Hans Demmelmair, Klingler, Mario, Klem, Sabrina, Demmelmair Hans, Koletzko Berthold, Sabrina Klem, Berthold Koletzko, Klem Sabrina, Koletzko, Berthold, Mario Klingler, Klingler Mario, Demmelmair, Hans   +11 more
core   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Long-chain PUFA supplementation in rural African infants: a randomized controlled trial of effects on gut integrity, growth, and cognitive development. [PDF]

, 2013
BACKGROUND: Intestinal damage and malabsorption caused by chronic environmental enteropathy are associated with growth faltering seen in infants in less-developed countries.
Drammeh, Saikou, Stephen Young, Andrew M Prentice, van der Merwe, Liandré F, Young, Stephen, Fulford, Anthony J, Halliday, Katherine E, Prentice, Andrew M, Saikou Drammeh, Sophie E Moore, Anthony J Fulford, Moore, Sophie E, Liandré F van der Merwe, Katherine E Halliday   +13 more
core   +1 more source