Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes [PDF]
Vesicular stomatitis virus (VSV) elicited cytotoxic thymus-derived lymphocytes (CTLs) in mice of the BALB/c and three congenic strains (BALB.b, BALB.k, BALB.HTG).
Baltimore, David+3 more
core +2 more sources
Bioreactor production of rVSV‐based vectors in Vero cell suspension cultures
The Vero cell line is the most used continuous cell line in viral vaccine manufacturing. Here, we further explored the Vero suspension system for rVSV‐based vector production. The cells were adapted to a serum‐free commercial medium and cultivated in bioreactors. Following small scale optimization and screening studies, bioreactor productions of highly
Sascha Kiesslich+4 more
wiley +1 more source
Comparisons of nucleotide sequences in the genomes of the New Jersey and Indiana serotypes of vesicular stomatitis virus [PDF]
Nucleotide sequences of around 200 residues were determined adjacent to the 3' terminus of the genome RNA of vesicular stomatitis virus, New Jersey serotype, and adjacent to the 3'-terminal polyadenylic acid tract of the N protein mRNA of the same virus.
C. R. Pringle+2 more
openaire +3 more sources
Estimating SARS-CoV-2 Infections from Deaths, Confirmed Cases, Tests, and Random Surveys [PDF]
There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely underestimates the number of infections, deaths lag infections substantially, while test positivity rates tend to greatly ...
arxiv +1 more source
Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization. [PDF]
BACKGROUND: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV (a ...
Addo, MM+22 more
core +1 more source
Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden+22 more
core +1 more source
Human T-cell immunoglobulin mucin 1 (hTIM-1) is known to promote cellular entry of enveloped viruses. Previous studies suggested that the polymorphisms of hTIM-1 affected its function.
Takanari Hattori+5 more
doaj +1 more source
Vesicular stomatitis virus vectors expressing avian influenza H5 HA induce cross-neutralizing antibodies and long-term protection [PDF]
Given the lethality of H5N1 avian influenza viruses (AIV) and the recurring spread from poultry to humans, an effective vaccine against H5N1 viruses may be needed to prevent a pandemic.
Buonocore, Linda+8 more
core +1 more source
Nipah shell disorder, modes of infection, and virulence [PDF]
The Nipah Virus (NiV) was first isolated during a 1998–9 outbreak in Malaysia. The outbreak initially infected farm pigs and then moved to humans from pigs with a case-fatality rate (CFR) of about 40%.
Dunker, A. Keith+3 more
core +1 more source
Comparison of the Serum Neutralization Test and a Competitive Enzyme-Linked Immunosorbent Assay for the Detection of Antibodies to Vesicular Stomatitis Virus New Jersey and Vesicular Stomatitis Virus Indiana [PDF]
A competitive enzyme-linked immunosorbent assay (C-ELISA) for the detection of antibodies against vesicular stomatitis virus New Jersey (VSV-NJ) and vesicular stomatitis virus Indiana (VSV-IN) was compared with the serum neutralization test (SNT) using 1,106 serum samples obtained from dairy cattle on sentinel study farms in the Poás region of Costa ...
Alvarado, Juan Francisco+4 more
openaire +4 more sources