Results 61 to 70 of about 32,892 (203)

Antigen presentation of post‐translationally modified peptides in major histocompatibility complexes

Immunology &Cell Biology, Volume 103, Issue 2, Page 161-177, February 2025.
T cells recognize pathogens and malignantly transformed cells through antigen presentation on major histocompatibility complex molecules. Post‐translational modifications (PTMs) of proteins can alter the peptides presented, influencing immune recognition and disease.
Alexine S de Wit, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Vesicular stomatitis virus (indiana 2 serotype) as experimental model to study acute encephalitis – morphological features
Vírus da estomatite vesicular (sorotipo indiana 2) como modelo experimental para o estudo de encefalite aguda – aspectos morfológicos

Semina: Ciências Biológicas e da Saúde, 2003
The Vesicular Stomatitis Virus (VSV) is a Vesiculovirus of the Rhabdoviridae family that infects mammals and causes vesicular lesions similar to those of foot-and-mouth disease. VSV experimental encephalitis can be induced in rodents and the symptoms are
Florêncio Figueiredo Cavalcanti Neto, Leila Maria Cardao Chimelli, Gisele Fabrino Machado   +2 more
doaj   +1 more source

Mpox Virus as a Global Public Health Emergency: A Scoping Review

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
The monkeypox (Mpox) virus has emerged as a global public health emergency of international concern recently. The virus that was endemic in West and Central Africa has now been reported with chains of global transmission to several countries. A scoping review was carried out from the relevant literature available from PubMed, Scopus and Web of Science.
Sathish Sankar, Pachamuthu Balakrishnan, Yean K. Yong, Sivadoss Raju, Vijayakumar Velu, Esaki M. Shankar, Marie Larsson, Sumi Mukhopadhyay   +7 more
wiley   +1 more source

UEG Week 2023 Poster Presentations

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 535-1498, October 2023.
wiley   +1 more source

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon Beta, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)

Blood, 2018
Background: Oncolytic virotherapy is a novel immunomodulatory therapeutic approach for relapsed refractory hematologic malignancies. The Indiana strain of Vesicular Stomatitis Virus (VSV) has been engineered to encode interferon beta (IFNβ) and sodium ...
Joselle M. Cook, K. Peng, B. Ginos, A. Dueck, Marissa Giers, N. Packiriswamy, B. Brunton, M. Patnaik, T. Witzig, F. Buadi, A. Dispenzieri, M. Gertz, R. Go, S. Hayman, J. Lust, D. Dingli, S. Rajkumar, N. Leung, R. Warsame, W. Gonsalves, T. Kourelis, Eli Muchtar, P. Bergsagel, S. Broski, P. Kapoor, R. Kyle, M. Siddiqui, A. Fonder, M. Hobbs, Y. Hwa, Yi Lin, Shaji K. Kumar, S. Russell, M. Lacy   +33 more
semanticscholar   +1 more source

Isolation and Characterization of Seneca Valley Virus From Pig Transboundary Spread to the Mink Infection

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Seneca Valley virus (SVV) infection has recently disseminated across pig farms in Canada, America, and China. The SVV has been identified in humans, rodents, and houseflies. Although cross‐species transmission events may lead to limited subsequent transmission, sustained outbreaks have been observed in new mammalian hosts.
Ziliang Qin, Xinmiao He, Chao Chen, Shaojun Chen, Zida Nai, Yao Wang, Wentao Wang, Gang Li, Fang Wang, Ming Tian, Haijuan He, Heshu Chen, Di Liu, Xinpeng Jiang, Chunfu Zheng   +14 more
wiley   +1 more source

Study of Glutoxim antiviral activity in the fibroblast cell line infected with vesicular stomatitis virus

Russian veterinary journal, 2018
New strategy for the treatment of animal infectious diseases is based upon the modulation of the host immune response in order to enhance the clearance of infectious agents and reduce the damaging effects of inflammation in the tissues.
Сергей Ожерелков, S. Ozherelkov, Татьяна Кожевникова, Tatyana N. Kozhevnikova, Александр Санин, A. Sanin, Ольга Конюшко, O. Konyushko, Михаил Ворович, M. Vorovich, Алла Иванова, A. Ivanova   +11 more
semanticscholar   +1 more source

Assessment of Single‐Cycle M‐Protein Mutated Vesicular Stomatitis Virus as a Safe and Immunogenic Mucosal Vaccine Platform for SARS‐CoV‐2 Immunogen Delivery

Advanced Science, Volume 11, Issue 47, December 18, 2024.
The VSVMT‐S2P vaccine candidate, featuring a SARS‐CoV‐2 pre‐fusion state spike protein mutant, is safe in healthy and immunocompromised animals. With only single inoculation via various routes of administration, VSVMT‐S2P can stimulate effective and comprehensive immune responses in vivo, especially via the intramuscular route.
En Zhang, Yong Ke, Weihong Ran, Yu Zhang, Ruihang Li, Xinkui Fang, Lei Wang, Baohong Zhang, Tao Sun   +8 more
wiley   +1 more source

Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution

Current Protocols, Volume 4, Issue 12, December 2024.
Abstract Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.
Francesco Costacurta, Stefanie Rauch, Dorothee von Laer, Emmanuel Heilmann   +3 more
wiley   +1 more source

Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements

Current Protocols, Volume 4, Issue 11, November 2024.
Abstract Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Stefanie Rauch, Francesco Costacurta, Dorothee von Laer, Emmanuel Heilmann   +3 more
wiley   +1 more source