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Vesicular Transport and Amyloids: The Growing Relationship
BiologicsProtein aggregation may lead to detrimental changes in brain and several other tissues. Amyloids or large protein aggregates are formed in different brain areas under multiple diseases classified as proteinopathies.
Arun Upadhyay
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VirulenceChlamydia infection is an important cause of public health diseases, and no effective vaccine is currently available. Owing to its unique intracellular lifestyle, Chlamydia requires a variety of nutrients and substrates from host cells, particularly ...
Lei Wenbo +3 more
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A chloroplast-localized vesicular transport system: a bio-informatics approach
BMC Genomics, 2004 Background The thylakoid membrane of higher plant chloroplasts is made of membrane lipids synthesized in the chloroplast envelope. As the inner envelope membrane and the thylakoid are separated by the aqueous stroma, a system for transporting newly ...
Sandelius Anna, Andersson Mats X
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Role of SNAREs in Unconventional Secretion—Focus on the VAMP7-Dependent Secretion
Frontiers in Cell and Developmental Biology, 2022 Intracellular membrane protein trafficking is crucial for both normal cellular physiology and cell-cell communication. The conventional secretory route follows transport from the Endoplasmic reticulum (ER) to the plasma membrane via the Golgi apparatus ...
Somya Vats, Thierry Galli, Thierry Galli
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mBio, 2021 Vesicular trafficking is a fundamental cellular process involved in material transport in eukaryotes, but the diversity of the intracellular compartments has prevented researchers from obtaining a clear understanding of the specific functions of ...
Shinuo Cao +4 more
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Contact, 2023 Cells maintain the specific lipid composition of distinct organelles by vesicular transport as well as non-vesicular lipid trafficking via lipid transport proteins. Oxysterol-binding proteins (OSBPs) are a family of lipid transport proteins that transfer
Rohan P. Singh +3 more
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Separations, 2022 Transmembrane protein 59 (TMEM59) is a type I transmembrane protein. However, the characterization and functions of TMEM59 in cells are not clear. Our results showed that TMEM59 localizes to vesicular structures.
Haifeng Wang, Tieqiao Wen
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Protein Interactions of the Vesicular Glutamate Transporter VGLUT1
PLoS ONE, 2014 Exocytotic release of glutamate depends upon loading of the neurotransmitter into synaptic vesicles by vesicular glutamate transporters, VGLUTs. The major isoforms, VGLUT1 and 2, exhibit a complementary pattern of expression in synapses of the adult rodent brain that correlates with the probability of release and potential for plasticity.
Magda S Santos +3 more
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Apical membrane proteins are transported in distinct vesicular carriers [PDF]
Current Biology, 2001 The function of polarized epithelial cells and neurons is achieved through intracellular sorting mechanisms that recognize classes of proteins in the trans-Golgi network (TGN) and deliver them into separate vesicles for transport to the correct surface domain.
Jacob, Ralf, Naim, Hassan Y.
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Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
BMC Biology, 2017 Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers.
Christopher J. Stefan +19 more
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