Results 11 to 20 of about 138,493 (297)
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. [PDF]
Nature, 2013 Newly synthesized proteins and lipids are transported across the Golgi complex via different mechanisms whose respective roles are not completely clear. We previously identified a non-vesicular intra-Golgi transport pathway for glucosylceramide (GlcCer)--
Burke JE +20 more
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Role of SNAREs in Unconventional Secretion—Focus on the VAMP7-Dependent Secretion
Frontiers in Cell and Developmental Biology, 2022 Intracellular membrane protein trafficking is crucial for both normal cellular physiology and cell-cell communication. The conventional secretory route follows transport from the Endoplasmic reticulum (ER) to the plasma membrane via the Golgi apparatus ...
Somya Vats, Thierry Galli, Thierry Galli
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Contact, 2023 Cells maintain the specific lipid composition of distinct organelles by vesicular transport as well as non-vesicular lipid trafficking via lipid transport proteins. Oxysterol-binding proteins (OSBPs) are a family of lipid transport proteins that transfer
Rohan P. Singh +3 more
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mBio, 2021 Vesicular trafficking is a fundamental cellular process involved in material transport in eukaryotes, but the diversity of the intracellular compartments has prevented researchers from obtaining a clear understanding of the specific functions of ...
Shinuo Cao +4 more
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Separations, 2022 Transmembrane protein 59 (TMEM59) is a type I transmembrane protein. However, the characterization and functions of TMEM59 in cells are not clear. Our results showed that TMEM59 localizes to vesicular structures.
Haifeng Wang, Tieqiao Wen
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Protein Interactions of the Vesicular Glutamate Transporter VGLUT1
PLoS ONE, 2014 Exocytotic release of glutamate depends upon loading of the neurotransmitter into synaptic vesicles by vesicular glutamate transporters, VGLUTs. The major isoforms, VGLUT1 and 2, exhibit a complementary pattern of expression in synapses of the adult rodent brain that correlates with the probability of release and potential for plasticity.
Magda S Santos +3 more
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Apical membrane proteins are transported in distinct vesicular carriers [PDF]
Current Biology, 2001 The function of polarized epithelial cells and neurons is achieved through intracellular sorting mechanisms that recognize classes of proteins in the trans-Golgi network (TGN) and deliver them into separate vesicles for transport to the correct surface domain.
Jacob, Ralf, Naim, Hassan Y.
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Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
BMC Biology, 2017 Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers.
Christopher J. Stefan +19 more
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VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles [PDF]
, 1992 In simple epithelial cells, apical and basolateral proteins are sorted into separate vesicular carriers before delivery to the appropriate plasma membrane domains.
Dupree, P. +6 more
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Vesicular protein transport [PDF]
The Pharmacogenomics Journal, 2001 Protein transport and sorting in the secretory and endocytic pathways via vesicles is required for organelle biogenesis, constitutive and regulated secretion and constitutive and regulated endocytosis. It is essential for a multicellular organism and the function of its specialised cell types that the multiple transport and sorting events are highly ...
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