Results 41 to 50 of about 138,493 (297)

The interrelated roles of RAB family proteins in the advancement of neoplastic growth

Frontiers in Oncology
Rab Proteins, A Subfamily Of The Ras Superfamily Of Small Gtpases, Are Critical Regulators Of Intracellular Vesicular Trafficking, Which Is Intricately Linked To Various Cellular Processes.
Yuxin Ji, Yuxin Ji, Ruonan Li, Ruonan Li, Guohui Tang, Guohui Tang, Wenrui Wang, Wenrui Wang, Changjie Chen, Changjie Chen, Qingling Yang, Qingling Yang, Qingling Yang   +12 more
doaj   +1 more source

Prion Aggregates Are Recruited to the Insoluble Protein Deposit (IPOD) via Myosin 2-Based Vesicular Transport.

PLoS Genetics, 2016
Aggregation of amyloidogenic proteins is associated with several neurodegenerative diseases. Sequestration of misfolded and aggregated proteins into specialized deposition sites may reduce their potentially detrimental properties.
Rajesh Kumar, Peter P Nawroth, Jens Tyedmers   +2 more
doaj   +1 more source

EhVps23: A Component of ESCRT-I That Participates in Vesicular Trafficking and Phagocytosis of Entamoeba histolytica

Frontiers in Cellular and Infection Microbiology, 2021
The endosomal sorting complex required for transport (ESCRT) is formed by ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III complexes, and accessory proteins. It conducts vesicular trafficking in eukaryotes through the formation of vesicles and membrane fission and ...
Ausencio Galindo, Rosario Javier-Reyna, Guillermina García-Rivera, Cecilia Bañuelos, Sarita Montaño, Jaime Ortega-Lopez, Bibiana Chávez-Munguía, Lizbeth Salazar-Villatoro, Esther Orozco   +8 more
doaj   +1 more source

Cytosolic Glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease [PDF]

, 2019
A new paradigm for Niemann-Pick C disease is presented where lysosomal storage leads to a deficit in cytoplasmic glucosylceramide (GlcCer) where it performs important functions.
Bhardwaj, Meenakshi, Haberkant, Per, Schmid, Ralf, Sillence, Daniel J., Tongue, Paige, Wheeler, S.   +5 more
core   +1 more source

Hijacking host cell vesicular transport: New insights into the nutrient acquisition mechanism of Chlamydia

Virulence
Chlamydia infection is an important cause of public health diseases, and no effective vaccine is currently available. Owing to its unique intracellular lifestyle, Chlamydia requires a variety of nutrients and substrates from host cells, particularly ...
Lei Wenbo, Yang Yewei, Zhou Hui, Li Zhongyu   +3 more
doaj   +1 more source

Molecular mechanisms of Sar/Arf GTPases in vesicular trafficking in yeast and plants

Frontiers in Plant Science, 2014
Small GTPase proteins play essential roles in the regulation of vesicular trafficking systems in eukaryotic cells. Two types of small GTPases, secretion-associated Ras-related protein (Sar) and ADP-ribosylation factor (Arf), act in the biogenesis of ...
Tomohiro eYorimitsu, Ken eSato, Masaki eTakeuchi   +2 more
doaj   +1 more source

GLTP mediated non-vesicular GM1 transport between native membranes. [PDF]

PLoS ONE, 2013
Lipid transfer proteins (LTPs) are emerging as key players in lipid homeostasis by mediating non-vesicular transport steps between two membrane surfaces. Little is known about the driving force that governs the direction of transport in cells.
Ines Lauria, Jan van Üüm, Esmina Mjumjunov-Crncevic, David Walrafen, Luis Spitta, Christoph Thiele, Thorsten Lang   +6 more
doaj   +1 more source

A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes

Life, 2023
Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo
Manuel Adrián Velázquez-Cervantes, Yazmín Rocío Benítez-Zeferino, Arturo Flores-Pliego, Addy Cecilia Helguera-Repetto, David Eduardo Meza-Sánchez, José Luis Maravillas-Montero, Guadalupe León-Reyes, Javier Mancilla-Ramírez, Jorge Francisco Cerna-Cortés, María Isabel Baeza-Ramírez, Moises León-Juaárez   +10 more
doaj   +1 more source

Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis. [PDF]

, 2015
BackgroundAlthough much is known about the mechanism of action of Bacillus thuringiensis Cry toxins, the target tissue cellular responses to toxin activity is less understood.
Bravo, Alejandra, Cancino-Rodezno, Angeles, Canton, Pablo Emiliano, Gill, Sarjeet S, Soberón, Mario   +4 more
core   +1 more source

The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis [PDF]

, 2015
Acknowledgements We wish to thank Jorge Galán, Gregory Pazour, Derek Toomre, Giuliano Callaini, Joel Rosenbaum, Alessandra Boletta and Francesco Blasi for generously providing reagents and for productive discussions, and Sonia Grassini for technical ...
A Batista, A Onnis, AC Smith, AH Hutagalung, AL Kullas, AW van der Velden, BT Keady, C Cassioli, C Geisler, C Margadant, C T Baldari, C Wasmeier, CJ Westlake, CP Horgan, DA MacLeod, DS Gomez, E Schonteich, EM Manders, F Finetti, F Finetti, F Finetti, G Bonello, G Iezzi, G Patino-Lopez, GJ Pazour, H Soares, I Jordens, JA Follit, JC Stinchcombe, JK Chen, K Geddes, L Patrussi, L Patrussi, LB Pedersen, LI Ehrlich, M de la Roche, M Esquerré, M Gottardo, M Kurowska, MV Nachury, N Capitani, NB Martín-Cófreces, RS Kalupahana, S Pacini, S Spanò, S Spanò, S Spanò, S Wang, SR McGlashan, SY Wong, V Das, VM Wu   +51 more
core   +1 more source