Non-vesicular Lipid Transport Machinery in Entamoeba histolytica
Eukaryotic cells are organized into separate membrane-bound compartments that have specialized biochemical signature and function. Maintenance and regulation of distinct identity of each compartment is governed by the uneven distribution and intra ...
Koushik Das, Tomoyoshi Nozaki
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The isolated ER-Golgi intermediate compartment exhibits properties that are different from ER and cis-Golgi [PDF]
A procedure has been established in Vero cells for the isolation of an intermediate compartment involved in protein transport from the ER to the Golgi apparatus. The two-step subcellular fractionation procedure consists of Percoll followed by Metrizamide
K Matter +7 more
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The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. [PDF]
Cargo selection and export from the endoplasmic reticulum is mediated by the COPII coat machinery that includes the small GTPase Sar1 and the Sec23/24 and Sec13/31 complexes.
Bannykh, Sergei +20 more
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Architecture of coatomer: Molecular characterization of delta-COP and protein interactions within the complex [PDF]
Copyright © 2011 by The Rockefeller University Press.Coatomer is a cytosolic protein complex that forms the coat of COP I-coated transport vesicles.
Faulstich, D +20 more
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The interrelated roles of RAB family proteins in the advancement of neoplastic growth
Rab Proteins, A Subfamily Of The Ras Superfamily Of Small Gtpases, Are Critical Regulators Of Intracellular Vesicular Trafficking, Which Is Intricately Linked To Various Cellular Processes.
Yuxin Ji +12 more
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Mistargeting of the lectin ERGIC-53 to the endoplasmic reticulum of HeLa cells impairs the secretion of a lysosomal enzyme [PDF]
ERGIC-53, a homo-oligomeric recycling protein associated with the ER-Golgi intermediate compartment (ERGIC), has properties of a mannose-selective lectin in vitro, suggesting that it may function as a transport receptor for glycoproteins in the early ...
Florence Vollenweider +7 more
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Aggregation of amyloidogenic proteins is associated with several neurodegenerative diseases. Sequestration of misfolded and aggregated proteins into specialized deposition sites may reduce their potentially detrimental properties.
Rajesh Kumar +2 more
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Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2) [PDF]
The polarized delivery of membrane proteins to the cell surface and the initial secretion of lysosomal proteins into the culture medium were studied in the polarized human intestinal adenocarcinoma cell line Caco-2 in the presence or absence of the ...
Hauri, H.P. +6 more
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The endosomal sorting complex required for transport (ESCRT) is formed by ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III complexes, and accessory proteins. It conducts vesicular trafficking in eukaryotes through the formation of vesicles and membrane fission and ...
Ausencio Galindo +8 more
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The role of motor proteins in endosomal sorting [PDF]
Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie +3 more
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