Protein kinase A activity is necessary for fission and fusion of Golgi to endoplasmic reticulum retrograde tubules. [PDF]
PLoS ONE, 2015 It is becoming increasingly accepted that together with vesicles, tubules play a major role in the transfer of cargo between different cellular compartments.
María J Tenorio +2 more
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Proteomic profile of serum from patients with schizophrenia spectrum disorders [PDF]
PeerJ, 2022 This article describes the most likely classes of proteins and molecular processes that specifically characterize schizophrenic spectrum disorders such as simple and paranoid schizophrenia, schizotypal disorder, and acute polymorphic psychotic disorder ...
Elena Dmitrieva +5 more
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Levetiracetam Affects Differentially Presynaptic Proteins in Rat Cerebral Cortex
Frontiers in Cellular Neuroscience, 2017 Presynaptic proteins are potential therapeutic targets for epilepsy and other neurological diseases. We tested the hypothesis that chronic treatment with the SV2A ligand levetiracetam affects the expression of other presynaptic proteins.
Daniele Marcotulli +7 more
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Analyses of vesicular transport within the endoplasmic reticulum-golgi interface in "Saccharomyces cerevisiae" [PDF]
, 2012 A characteristic feature of every eukaryotic cell is its division into different compartments. This subdivision into different intracellular organelles like the endoplasmic reticulum (ER), the Golgi apparatus or the endosomal/lysosomal system enables ...
Diefenbacher, Melanie
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Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]
, 2010 The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter, Günter Müller
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Golgi Apparatus Regulates Plasma Membrane Composition and Function
Cells, 2022 Golgi apparatus is the central component of the mammalian secretory pathway and it regulates the biosynthesis of the plasma membrane through three distinct but interacting processes: (a) processing of protein and lipid cargoes; (b) creation of a sharp ...
Ilenia Agliarulo +1 more
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Characterization of p28, a novel ERGIC/"cis"-Golgi protein, required for Golgi ribbon formation. pH measurements in the early secretory pathway "in vivo" [PDF]
, 2008 The secretory pathway of mammalian cells consists of several compartments. Transport between these organelles is accomplished via vesicular carriers or maturation. For non abundant proteins it is thought that transport receptors help the proteins to exit
Kögler, Eva Jutta
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The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles [PDF]
, 2000 Members of the yeast p24 family, including Emp24p and Erv25p, form a heteromeric complex required for the efficient transport of selected proteins from the endoplasmic reticulum (ER) to the Golgi apparatus.
Muñiz Guinea, Manuel +11 more
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Synergies in exosomes and autophagy pathways for cellular homeostasis and metastasis of tumor cells
Cell & Bioscience, 2020 Background Eukaryotic cells demonstrate two tightly linked vesicular transport systems, comprising intracellular vesicle transport and extracellular vesicle transport system.
Leila Salimi +9 more
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Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
, 2007 Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas +15 more
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