Results 41 to 50 of about 188,914 (350)

The intrinsic stiffness of human trabecular meshwork cells increases with senescence. [PDF]

, 2015
Dysfunction of the human trabecular meshwork (HTM) plays a central role in the age-associated disease glaucoma, a leading cause of irreversible blindness.
Chang, Yow-Ren, Morgan, Joshua T, Murphy, Christopher J, Raghunathan, Vijay Krishna, Russell, Paul   +4 more
core   +6 more sources

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]

, 2018
Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton, A Desmouliere, A Holmes, A Yabuki, AA Eddy, AA Eddy, AC Sanchez-Lara, BL Aken, C Grupp, C. P. D. Wheeler-Jones, CH Heldin, CL Marino, E Honda, E Van Obberghen-Schilling, F Strutz, F Strutz, F Syeda, GR Grotendorst, H. M. Syme, HP Rodemann, J Ivaska, J Lu, J. Elliott, J. S. Lawson, JL Mumaw, JS Lawson, K Sawashima, KG McCullagh, KJ Kelynack, LC Penning, M Prunotto, M Zeisberg, MA Venkatachalam, MJ Ryan, MK Phanish, ML Sequeira Lopez, P Boor, P Sysa, PC Bartlett, Q Chai, RA Ignotz, S Chakrabarti, S Meran, S Moll, S Neelisetty, SC Chen, SL Lin, SP DiBartola, SW Smith, T Akamatsu, TA Wynn, V Dugina, VS Lebleu, W Bloom, WA Border, X Pan, XM Meng, Y Hosokawa, Y Liu   +58 more
core   +2 more sources

Exploring the Potential of Extracellular Vesicles from Atlantic Cod (Gadus morhua L.) Serum and Mucus for Wound Healing In Vitro

Biology
Novel therapeutic approaches for wound healing have included biomaterials from the Atlantic cod (Gadus morhua L.), with promising results in wound management.
Stefania D’Alessio, Igor Kraev, Bergljót Magnadóttir, Sigrun Lange   +3 more
doaj   +1 more source

Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]

, 2016
open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio, Bernardini, Nunzia, Blandizzi, Corrado, Buccianti, Piero, Campani, Daniela, Castagna, Maura, Colucci, Rocchina, Di Candio, Giulio, Dolfi, Amelio, ERREDE, Mariella, GIROLAMO, FRANCESCO, Ippolito, Chiara, Segnani, Cristina, Tirotta, Erika, Villanacci, Vincenzo, VIRGINTINO, Daniela   +15 more
core   +2 more sources

The Hydration of Vimentin

Ophthalmic Research, 1993
The hydration of vimentin isolated from the cortex of bovine lenses was studied by thermal analysis. Differential scanning calorimetry between -30, and 30 degrees C provided the freezable water content, and thermogravimetric analysis up to 105 degrees C yielded the total water content. The difference between the two gives the nonfreezable water content
S K, Kakar, F A, Bettelheim
openaire   +2 more sources

Vimentin fibers orient traction stress [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance Vimentin is a marker for the epithelial-to-mesenchymal transition, which is thought to lead to cancer metastasis. Without vimentin, planar cells exhibit polarity defects and cannot migrate as single cells. The mechanisms by which vimentin influences cell migration remain mostly unknown, however.
Nancy Costigliola, Liya Ding, Christoph J. Burckhardt, Sangyoon J. Han, Edgar Gutierrez, Andressa Mota, Alex Groisman, Timothy J. Mitchison, Gaudenz Danuser   +8 more
openaire   +2 more sources

Vimentin: from a cytoskeletal protein to a critical modulator of immune response and a target for infection

Frontiers in Immunology, 2023
Vimentin is an intermediate filament protein that plays a role in cell processes, including cell migration, cell shape and plasticity, or organelle anchorage.
Jeffrey Arrindell, Jeffrey Arrindell, Benoit Desnues, Benoit Desnues   +3 more
doaj   +1 more source

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]

, 2016
Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C, CARDINALI, CLAUDIO, GISMONDI, Angela, MORELLI, MARIA BEATRICE, Nabissi, M, Santoni, G., Santoni, M   +6 more
core   +1 more source

Focused low-intensity pulsed ultrasound upregulates Vimentin protein expression to inhibit chondrocyte apoptosis

陆军军医大学学报, 2023
Objective To investigate the molecular mechanism of focused low-intensity pulsed ultrasound (FLIPUS) to inhibit chondrocyte apoptosis through mechanical effects.
LI Dongqian, YE Haixia, YU Lehua, JIA Lang   +3 more
doaj   +1 more source

Immunohistochemical characteristics of epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma

Zaporožskij Medicinskij Žurnal
The epithelial-mesenchymal transition (EMT) plays a crucial role in the development of pancreatic ductal adenocarcinoma (PDAC). There are insufficient and contradictory data in the scientific literature on the peculiarities of epithelial and mesenchymal ...
M. A. Shyshkin, V. O. Kabachenko
doaj   +1 more source