Results 41 to 50 of about 66,916 (254)
Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]
, 2016 Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C +6 more
core +1 more source
BiologyNovel therapeutic approaches for wound healing have included biomaterials from the Atlantic cod (Gadus morhua L.), with promising results in wound management.
Stefania D’Alessio +3 more
doaj +1 more source
Frontiers in Immunology, 2023 Vimentin is an intermediate filament protein that plays a role in cell processes, including cell migration, cell shape and plasticity, or organelle anchorage.
Jeffrey Arrindell +3 more
doaj +1 more source
Ophthalmic Research, 1993 The hydration of vimentin isolated from the cortex of bovine lenses was studied by thermal analysis. Differential scanning calorimetry between -30, and 30 degrees C provided the freezable water content, and thermogravimetric analysis up to 105 degrees C yielded the total water content. The difference between the two gives the nonfreezable water content
S K, Kakar, F A, Bettelheim
openaire +2 more sources
Vimentin fibers orient traction stress [PDF]
Proceedings of the National Academy of Sciences, 2017 Significance Vimentin is a marker for the epithelial-to-mesenchymal transition, which is thought to lead to cancer metastasis. Without vimentin, planar cells exhibit polarity defects and cannot migrate as single cells. The mechanisms by which vimentin influences cell migration remain mostly unknown, however.
Nancy Costigliola +8 more
openaire +2 more sources
Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
, 2016 open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
core +2 more sources
陆军军医大学学报, 2023 Objective To investigate the molecular mechanism of focused low-intensity pulsed ultrasound (FLIPUS) to inhibit chondrocyte apoptosis through mechanical effects.
LI Dongqian +3 more
doaj +1 more source
Zaporožskij Medicinskij ŽurnalThe epithelial-mesenchymal transition (EMT) plays a crucial role in the development of pancreatic ductal adenocarcinoma (PDAC). There are insufficient and contradictory data in the scientific literature on the peculiarities of epithelial and mesenchymal ...
M. A. Shyshkin, V. O. Kabachenko
doaj +1 more source
eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts [PDF]
, 2016 Background: We have previously shown that the eukaryotic elongation factor subunit 1B gamma (eEF1Bγ) interacts with the RNA polymerase II (pol II) alpha-like subunit “C” (POLR2C), alone or complexed, in the pol II enzyme. Moreover, we demonstrated that
Ammassari-teule, Martine +9 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source