Results 131 to 140 of about 900,097 (207)

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

Glia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans, Annika Mordelt, Marta Guevara‐Ferrer, Katrin Linda, Denise Duineveld, Sofia Puvogel, Marina P. Hommersom, Nicky Scheefhals, Lisa Rahm, Emma Dyke, Gijs‐Jan Scholten, Caroline Knorz, Carlos Gonzalez Jimenez, Noelle van Egmond, Astrid Oudakker, Chantal Bijnagte‐Schoenmaker, Hans van Bokhoven, Wei Wei, Samuel Hofmann, Sabine Jung‐Klawitter, Sandra Mojica‐Perez, Jack Parent, Lidia Carotenuto, Sarah Weckhuysen, Nadine Maas, Ype Elgersma, Eline van de Ven, Dirk Lefeber, Anita Lygeroudi, Helga E. de Vries, Luc Jordi, Magdalini Polymenidou, Teresa Mitchell‐Garcia, Iulia Dragan, Amalia Dolga, Lot D. de Witte, Clara D. M. van Karnebeek, James Ellis, Alejandro Garanto, Nael Nadif Kasri   +39 more
wiley   +1 more source

Materials and Music: Selective Imperfection as a Generative Framework for Analysis, Creativity and Discovery

Interdisciplinary Materials, Volume 5, Issue 5, Page 834-867, September 2026.
Vibrations in matter, from spider webs to molecules, water to flames, share a grammar with music. We propose that creativity emerges when constraints force expansion beyond existing possibilities. Selective imperfection restores balance, enabling invention.
Markus J. Buehler
wiley   +1 more source

Interactive mechanisms between caveolin-1 and actin filaments or vimentin intermediate filaments instruct cell mechanosensing and migration. [PDF]

J Mol Cell Biol, 2023
Tang D, Zhang Y, Mei J, Zhao J, Miao C, Jiu Y.   +5 more
europepmc   +1 more source

Macrophages form dendrite-like pseudopods to enhance bacterial ingestion

The EMBO Journal
Macrophages are critical innate immune cells that exhibit remarkable adaptability during pathogen infections. However, the relationship between their morphological plasticity and physiological functions remains largely elusive.
Changyuan Fan, Xinyi Huang, Jie Mei, Xuemeng Shi, Hao Zhang, Cong Liang, Shuzhi Cui, Yifan Xing, Biao Cao, Wei Liu, Huisheng Liu, Bo Liu, Wakam Chang, Mengle Shao, Gong-Hong Wei, Yan-Jun Liu, Zheng-Jun Chen, Zhaoyu Lin, Tao Xu, Yaming Jiu   +19 more
doaj   +1 more source

Consequences of plectin ablation on the various intermediate filament systems in skeletal muscle

European Journal of Cell Biology
Plectin, a highly versatile and multifunctional cytolinker, acts as a central connector of the intermediate filament (IF) and other cytoskeletal systems.
Marta Rocha, Jonas Petsch, Dorothea Schultheis, Michaela M. Zrelski, Petra Fichtinger, Inga Koneczny, Samuel Meier-Menches, Gerhard Wiche, Rolf Schröder, Lilli Winter   +9 more
doaj   +1 more source

Zea mays Drought‐Overly Sensitive1/TUBA4 Is Wilty3, and Transcriptome Co‐Expression Analysis of Shoot Meristem Mutant Tissues Reveals Wilty2/TUB6:Wi3 Interactions Associated With Stem Vascular Bundle Development

Plant Direct, Volume 10, Issue 9, September 2026.
ABSTRACT Plant vasculature is essential for the transport of water, nutrients, and signaling molecules across organs, while also providing critical mechanical support for growth and development. Disruptions in vascular bundle formation can therefore lead to severe physiological and developmental defects.
Anuradha Dhingra, Indra Adhikari, Christopher D. Rock   +2 more
wiley   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, Volume 26, Issue 9, Page 6-23, September 2026.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

Effects of Vimentin Intermediate Filaments on the Structure and Dynamics of In Vitro Multicomponent Interpenetrating Cytoskeletal Networks. [PDF]

Phys Rev Lett, 2021
Shen Y, Wu H, Lu PJ, Wang D, Shayegan M, Li H, Shi W, Wang Z, Cai LH, Xia J, Zhang M, Ding R, Herrmann H, Goldman R, MacKintosh FC, Moncho-Jordá A, Weitz DA.   +16 more
europepmc   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

Small, Volume 22, Issue 49, 1 September 2026.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova, Olivera Valentirović Dann, Jennifer B. Schwarzkopf, Tengku I. Maulana, Jamina S. Gerhardus, Leon Kaysan, Katja Meier, Andreas Blaeser, Beate K. Straub, Holger Gerhardt, Ulrike A. Nuber   +10 more
wiley   +1 more source

Vimentin intermediate filaments and filamentous actin form unexpected interpenetrating networks that redefine the cell cortex. [PDF]

Proc Natl Acad Sci U S A, 2022
Wu H, Shen Y, Sivagurunathan S, Weber MS, Adam SA, Shin JH, Fredberg JJ, Medalia O, Goldman R, Weitz DA.   +9 more
europepmc   +1 more source