Results 111 to 120 of about 44,757 (227)

Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design [PDF]

open access: yes, 2009
Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new
Keserű, György Miklós   +2 more
core  

Neuritis and vinblastine-induced axonal transport disruption lead to signs of altered dorsal horn excitability

open access: yesMolecular Pain, 2018
Background Many patients with neuropathic pain present without signs of nerve injury on routine clinical examination. Some of these patients may have inflamed peripheral nerves (neuritis).
Ieva Satkeviciute, Andrew Dilley
doaj   +1 more source

Interaction of rat liver lysosomal membranes with actin. [PDF]

open access: yes, 1984
Membranes were prepared from lysosomes purified 80-fold by centrifugation in a discontinuous metrizamide gradient. When salt-washed membranes were combined with rabbit muscle actin, an increase in viscosity could be measured using a falling ball ...
Bame, KJ, Mehrabian, M, Rome, LH
core  

In vitro sensitivity testing of human renal cell carcinoma with cytostatic agents and interferon alpha-2a [PDF]

open access: yes, 1991
AC Buzaid   +32 more
core   +1 more source

A case of primary Hodgkin's lymphoma of the parotid gland. Case report and differentian diagnosis from Kuttner's Syndrom [PDF]

open access: yes, 2018
We report a rare case of primary Hodgkin’s lymphoma (HL) of the submandibular gland, with initially diagnosis of Kuttner’s Syndrom. A 48 years old man was referred to our hospital foe evaluation of a submandibular mass.
Di Cello, P.   +8 more
core  

STUDY OF STABILITY OF CELL CARRIERS AND CELLULAR FORMS OF VINKRISTIN AND VINBLASTIN IN STORAGE

open access: yesРазработка и регистрация лекарственных средств, 2019
Employees of the department of pharmaceutical chemistry and phar-maceutical technology received modified forms of terpene-indole alkaloids (TIA) - vincristine (VCR) and vinblastine (VBL) known in the therapy of oncological diseases by incorporating them ...
O. V. Trineeva, A. J. Halahakoon
doaj  

Effect of Vincristine and Vinblastine from Vinca Rosa on Microtubulues of Tumor H22 Cell Line

open access: yesDiyala Journal of Medicine, 2019
Background: Vinca alkaloids ( vincristine and vinblastine)  are microtubular toxins of chemically similar nature that disrupt microtubule function by binding to a site on β-tubulin and suppressing microtubule dynamics.
Ibrahim H Mohammed
doaj   +2 more sources

Vinca Alkaloids

open access: yesInternational Journal of Preventive Medicine, 2013
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects.
Maryam Moudi   +3 more
doaj  

Extraction of medicinal compounds from botanicals using bulk liquid membrane in rotating film contactor: Recovery of vinblastine from catharanthus roseus.

open access: yesIraqi Journal of Chemical and Petroleum Engineering, 2009
The interest of application of liquid membrane (pertraction) processes for recovery of medicinal compounds from dilute ammoniacal leach solutions is demonstrated.
Adil A. Al-Hemiri   +2 more
doaj  

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