Results 111 to 120 of about 31,171 (226)

Sequence Inversion Dictates the Antiproliferative Activity of Bidirectional Tryptophan‐Containing Dipeptide Libraries

open access: yesJournal of Peptide Science, Volume 32, Issue 10, October 2026.
Reversing the peptide backbone sequence of novel tryptophyl‐dipeptides uncovers profound changes in synthetic accessibility and antineoplastic profiles against human solid tumors. Phenotypic screening identifies a conformationally restricted lead architecture that achieves sub‐micromolar growth inhibition, confirming sequence topology as a critical ...
J. Benamer Díaz   +3 more
wiley   +1 more source

Vinblastine [PDF]

open access: yesReactions Weekly, 2020
openaire   +2 more sources

Response evaluation of neoadjuvant therapy in MIBC: clinical trial‐derived evidence to guide practice

open access: yesBJU International, Volume 138, Issue 4, Page 558-564, October 2026.
Objectives To review how response to neoadjuvant therapy (NAT) is assessed in clinical trials of muscle‐invasive bladder cancer (MIBC), and to determine whether trial‐derived evidence can inform response evaluation in contemporary practice. Subjects/Patients and Methods We searched PubMed, Embase and ClinicalTrials.gov through August 2025 for ...
Roberto Contieri   +9 more
wiley   +1 more source

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

open access: yesHIV Medicine, Volume 27, Issue 10, Page 1715-1721, October 2026.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart   +10 more
wiley   +1 more source

Antitumour Effects and Pharmacokinetics of Combination of Vinblastine with a Staurosporine Derivative, NA-382, in P388/ADR-bearing Mice

open access: yes, 1995
The effects of a staurosporine derivative, N-ethoxycarbonyl-7-oxostaurosporine (NA-382), on the pharmacokinetics of vinblastine were evaluated, compared with those of verapamil, in multidrug-resistant P388/ADR-bearing mice.
Shinya Wakusawa   +4 more
core   +1 more source

STUDY OF STABILITY OF CELL CARRIERS AND CELLULAR FORMS OF VINKRISTIN AND VINBLASTIN IN STORAGE

open access: yesРазработка и регистрация лекарственных средств, 2019
Employees of the department of pharmaceutical chemistry and phar-maceutical technology received modified forms of terpene-indole alkaloids (TIA) - vincristine (VCR) and vinblastine (VBL) known in the therapy of oncological diseases by incorporating them ...
O. V. Trineeva, A. J. Halahakoon
doaj  

Tumor growth delay and cell survival after treatment with irradiation and vinblastine

open access: yes, 1979
The interaction of irradiation and vinblastine was investigated in a solid rat rhabdomyosarcoma. Growth delay of the tumor and cell survival by an in vitro assay were the endpoints measured. Vinblastine was administered at a dose of 1.5 mg/kg body weight
Janse, H.C., Kal, H.B., Barendsen, G.W.
core   +1 more source

Quality of life with nivolumab and AVD first‐line treatment of Hodgkin lymphoma in the Phase II GHSG NIVAHL trial

open access: yes
HemaSphere, Volume 10, Issue 10, October 2026.
Christian Peter Jaworek   +12 more
wiley   +1 more source

Vinca Alkaloids

open access: yesInternational Journal of Preventive Medicine, 2013
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects.
Maryam Moudi   +3 more
doaj  

Glutamic acid and tryptophan do not prevent vinblastine‐induced apoptosis in a human lymphoma cell line

open access: yes, 1994
. The amino acids glutamic acid and tryptophan reportedly reverse the antitumour effect of the cancer chemotherapeutic drug vinblastine. Recent studies have shown that a large part of vinblastine's antitumour effect is due to induction of apoptosis.
Ishii, H., Allan, D. J., Harmon, B. V.
core   +1 more source

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