Results 101 to 110 of about 31,171 (226)
Design and Synthesis of Novel Biginelli Adducts: Anticancer Activity and In Silico Study
Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.Compound 8n emerged as the most potent agent against MCF‐7 cells, inducing apoptosis and cell cycle arrest. Molecular docking identified Eg5 kinesin as a potential target, highlighting these derivatives as promising leads for cancer therapeutics.
Aida Iraji +6 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Cavitary lung lesions are commonly attributed to infection; however, malignancy should remain a diagnostic consideration. We report a 30‐year‐old non‐smoking man with a history of treated Hodgkin lymphoma who presented with a cavitary pulmonary adenocarcinoma. This case highlights the importance of considering rare malignant causes.
Hosam Aldalbahi, Nora Ahmed Bedaiwi
wiley +1 more source
Isolation and screening of Vinblastine from Endophytic Fungi
, 2015 M.Sc. (Biotechnology)Vinblastine is a chemotherapeutic drug often used for the treatment of bladder cancer. Vinblastine belongs to the group called vinea alkaloids, obtained from plants Cathramhus roseus (famiJy- Apocyanaceae), species occurring in ...
Handa, Geetali
core
Food Science &Nutrition, Volume 14, Issue 10, October 2026.This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source
Effect of Vincristine and Vinblastine from Vinca Rosa on Microtubulues of Tumor H22 Cell Line
Diyala Journal of Medicine, 2019 Background: Vinca alkaloids ( vincristine and vinblastine) are microtubular toxins of chemically similar nature that disrupt microtubule function by binding to a site on β-tubulin and suppressing microtubule dynamics.
Ibrahim H Mohammed
doaj +2 more sources
Molecular Pain, 2018 Background Many patients with neuropathic pain present without signs of nerve injury on routine clinical examination. Some of these patients may have inflamed peripheral nerves (neuritis).
Ieva Satkeviciute, Andrew Dilley
doaj +1 more source
Effects of colchicine and vinblastine on in vitro gastric secretion.
, 1979 The effects of colchicine and vinblastine on in vitro bullfrog gastric mucosal preparations were studied with respect to H+ and pepsinogen secretion. In the concentration range of 1--50 mM, an initial but transient colchicine-mediated stimulation of H ...
G S Gordon, D K Kasbekar
core +1 more source
eJHaem, Volume 7, Issue 5, October 2026.ABSTRACT Erdheim–Chester disease (ECD) is a rare histiocytic disorder with heterogeneous clinical manifestations. Central nervous system (CNS) involvement is associated with poor prognosis. Although targeted therapies have improved outcomes in patients with mitogen‐activated protein kinase (MAPK) pathway alterations, optimal treatment strategies for ...
Naoki Watanabe +8 more
wiley +1 more source
Cytotoxicity of Esculetin Compared with Vinblastine and Paclitaxel in PC-3 Prostate Cancer Cells
Current OncologyBackground/Objectives: Metastatic prostate cancer is among the therapy-resistant human neoplasms. PC-3 is a commonly used experimental cell line that does not express androgen receptors.
Ana I. García-Pérez +4 more
doaj +1 more source
Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment
MedComm, Volume 7, Issue 10, October 2026.This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen +9 more
wiley +1 more source