Results 91 to 100 of about 31,171 (226)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Serial growth plate monitoring in a 3‐month‐old Labrador retriever receiving vinblastine chemotherapy

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐month‐old, male, entire Labrador retriever was presented for evaluation of a congenital mast cell tumour of the right pinna. Pinnectomy and regional lymphadenectomy confirmed a high‐grade mast cell tumour with nodal pre‐metastasis. Eight vinblastine chemotherapy treatments were administered over 12 weeks.
Paige A. A. Brown   +2 more
wiley   +1 more source

Vinblastine chemotherapy in adult patients with langerhans cell histiocytosis: a multicenter retrospective study

open access: yesOrphanet Journal of Rare Diseases, 2017
Background Vinblastine is the standard treatment for children with Langerhans cell histiocytosis (LCH). Whether this treatment could be extended to adults with LCH is questionable.
Abdellatif Tazi   +14 more
doaj   +1 more source

Chemotherapy of disseminated cutaneous classic Kaposi's sarcoma with vinblastine

open access: yes, 2002
Classic Kaposi's Sarcoma (KS) is a rare indolent cutaneous malign proliferative disease affecting predominantly elderly men of Mediterranean and Jewish origin. Classic KS generally does not require treatment for a prolonged time.
Sari, I   +6 more
core   +1 more source

Risk Factors for Pathologic Fracture in Dogs With Confirmed or Suspected Appendicular Osteosarcoma Treated With Low‐ or Standard‐Dose‐Rate Palliative External Beam Radiation Therapy

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 6, November 2026.
ABSTRACT Pathologic fracture is a complication of bone cancer with probable increased risk following radiation therapy (RT). Low‐dose‐rate (LDR) RT can spare late‐responding normal tissues by allowing intrafraction DNA repair, which could also impact tumor response. This retrospective cohort study evaluated efficacy and fracture rate in canine patients
Andrew Kurtzman   +5 more
wiley   +1 more source

A case of multisystem Langerhans cell histiocytosis presenting as central diabetes insipidus

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2019
Langerhans cell histiocytosis (LCH) is a rare malignancy most commonly characterized by histiocytic infiltration of bone. LCH lesions in the skull place the adjacent central nervous system (CNS) at risk for involvement, which can manifest as central ...
P. Daniel Nicholas, Ian Garrahy
doaj   +1 more source

Effect of some chemotherapy drugs) vincristine and vinblastine) on females albino mice fertility and sex hormones level

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2010
The aim of this study was to determine the effect of chemotherapy (vincristine and vinblastine) on the fertility and sex hormones level of female mice. Twenty four female albino mice were divided into three equal groups.
Hazim I. A. Al-Ahmed
doaj   +1 more source

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

open access: yesInternational Journal of Cancer, Volume 159, Issue 8, Page 1962-1973, 15 October 2026.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold   +12 more
wiley   +1 more source

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

open access: yesPediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez   +8 more
wiley   +1 more source

Tubulin aggregation and disaggregation: mediation by two distinct vinblastine-binding sites [PDF]

open access: yes, 1976
Rat brain tubulin possesses two distinct binding sites for vinblastine per molecule: a high-affinity site with an affinity constant of 6.2 X 106 M-1 and a low-affinity site with an affinity constant of 8 X 104 M-1.
Bhattacharyya, B., Wolff, J.
core   +1 more source

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