Results 71 to 80 of about 24,082 (195)
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
مجلة بغداد للعلوم, 2010 This study on the plant of Ain –AL Bason Catharanthus roseous showed the ability of callus cells that is produced by In Vitro culture technique and transformed to the accumulated media (MS 40gm/L sucrose ,2gm/L IAA Indole acetic acid , 0.5gm/L Tryptophan)
Baghdad Science Journal
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian +7 more
wiley +1 more source
STUDY OF STABILITY OF CELL CARRIERS AND CELLULAR FORMS OF VINKRISTIN AND VINBLASTIN IN STORAGE
Разработка и регистрация лекарственных средств, 2019 Employees of the department of pharmaceutical chemistry and phar-maceutical technology received modified forms of terpene-indole alkaloids (TIA) - vincristine (VCR) and vinblastine (VBL) known in the therapy of oncological diseases by incorporating them ...
O. V. Trineeva, A. J. Halahakoon
doaj
Advanced Science, Volume 13, Issue 35, 24 June 2026.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Molecular Pain, 2018 Background Many patients with neuropathic pain present without signs of nerve injury on routine clinical examination. Some of these patients may have inflamed peripheral nerves (neuritis).
Ieva Satkeviciute, Andrew Dilley
doaj +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Background The optimal number of chemotherapy cycles prior to maintenance avelumab in frontline metastatic urothelial cancer (mUC) remains unknown. We hypothesize that baseline characteristics can identify which patients will complete six cycles of chemotherapy without radiographic disease progression, versus those who may benefit from ...
Francesca Jackson‐Spence +11 more
wiley +1 more source
Malignant Ovarian Germ Cell Tumor—Survival and Reproductive Outcomes and Patterns of Relapse
Cancer Medicine, Volume 15, Issue 6, June 2026.BLURB FOR ETOC: Patients presenting with advanced MOGCT can be offered fertility‐sparing surgery after neoadjuvant chemotherapy with no detriment in oncological outcome. ABSTRACT Background Malignant ovarian germ cell tumors [MOGCT] are rare cancers affecting young women and often present in advanced stages.
Sayak Dey +24 more
wiley +1 more source
International Journal of Preventive Medicine, 2013 Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects.
Maryam Moudi +3 more
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Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.Humboldtia sanjappae bark extract evaluated for its anti‐inflammatory potential using in vivo paw edema models and in silico molecular docking. Bioactive flavonoids, particularly neoeriocitrin, showed strong interactions with TNF‐α, COX‐2, IL‐6, and IL‐1β, highlighting the extract's multi‐target anti‐inflammatory activity and therapeutic promise ...
Jameema Sidhic +10 more
wiley +1 more source