Results 71 to 80 of about 44,757 (227)
Immune‐related adverse events in the treatment of Hodgkin lymphoma with immune checkpoint inhibitors
British Journal of Haematology, EarlyView.Summary Immune checkpoint inhibitors (ICIs) have shown to be effective in the treatment of Hodgkin lymphoma (HL). ICI treatment is associated with the occurrence of a series of immune‐related adverse events (irAEs). We conducted an ambispective observational study on 96 patients with relapsed/refractory HL treated with ICIs to determine the incidence ...
Lisa Argnani +9 more
wiley +1 more source
Determination and Quantification of the Vinblastine Content in Purple, Red, and White Catharanthus Roseus Leaves Using RP-HPLC Method [PDF]
Advanced Pharmaceutical Bulletin, 2018 Purpose: To determine and quantify vinblastine in different varieties of Catharanthus roseus using reversed-phase HPLC method. Methods: The liquid chromatographic separation was performed using a reversed phase C18, Microsorb - MV column (250 mm x 4.6 mm,
Rohanizah Abdul Rahim +3 more
doaj +1 more source
Non-Hodgkin Lymphoma in Children and Adolescents: Progress Through Effective Collaboration, Current Knowledge, and Challenges Ahead [PDF]
, 2015 Non-Hodgkin lymphoma is the fourth most common malignancy in children, has an even higher incidence in adolescents, and is primarily represented by only a few histologic subtypes. Dramatic progress has been achieved, with survival rates exceeding 80%, in
Auperin, Anne +23 more
core +1 more source
British Journal of Haematology, EarlyView.Multimodal integration of sex‐ and age‐related immune‐gene signatures with baseline tumor burden (TMTV1) improves prediction of treatment response in adolescents and young adults with classical Hodgkin lymphoma. Summary The study investigates how sex and age influence treatment response in paediatric, adolescent and young adult (AYA) classical Hodgkin ...
Valli De Re +54 more
wiley +1 more source
Effect of Achillea santolina on mice spermatogenesis [PDF]
, 2004 Achillea santolina, a common variety of Achillea in Golestan province of Iran has been used in traditional medicine for its anti - inflammatory properties.
Azadbakht, M. +4 more
core +1 more source
Micropropagation for the production of high quality phytochemicals [PDF]
, 2013 Plants area source of many valuable secondary metabolites that find a broad field of applications, ranging from the agrochemical to the pharmaceutical industries.
Grevenstuk, Tomás, Romano, Anabela
core +1 more source
Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]
, 2015 Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu +3 more
core +1 more source
BJU International, EarlyView.Objective To evaluate the concordance between clinical complete response (cCR) and pathological complete response (pCR) in muscle‐invasive bladder cancer (MIBC) to assess the surrogacy and prognostic value of cCR for guiding bladder‐sparing strategies.
Navid Roessler +15 more
wiley +1 more source
Modifications on the Basic Skeletons of Vinblastine and Vincristine
Molecules, 2012 The synthetic investigation of biologically active natural compounds serves two main purposes: (<em>i</em>) the total synthesis of alkaloids and their analogues; (<em>ii</em>) modification of the structures for producing more ...
Csaba Szántay +3 more
doaj +1 more source
Modeling the Effects of Drug Binding on the Dynamic Instability of Microtubules
, 2011 We propose a stochastic model that accounts for the growth, catastrophe and rescue processes of steady state microtubules assembled from MAP-free tubulin.
Correia J J +8 more
core +1 more source