Results 81 to 90 of about 24,123 (191)

Hodgkin lymphoma of the ampulla of Vater: A rare cause of obstructive jaundice in children

JPGN Reports, Volume 7, Issue 3, Page 398-402, August 2026.
Abstract Hodgkin lymphoma (HL) has a wide spectrum of presentation. Most cases affect lymph nodes (nodal), while extranodal involvement is rare. Whereas the gastrointestinal tract is enriched with lymphoid tissues, the ampulla of Vater is not rich in lymphoid tissue. Involvement of the ampulla of Vater with HL has rarely been reported in adults and has
Sultana Alshammari, Homoud Alhebbi, Awad Al Qahtani, Sarah Algubaisi, Faisal Alhaffaf, Abdulrahman Al Robayan, Mohammed Almutairi, Saeed Alshieban, Mohammad Alshahrani, Tarek Khaled Alfawzan, Khalid Alkhamis, Ibrahim Al Hasan, Sami Wali   +12 more
wiley   +1 more source

Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 8, August 2026.
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng, Shuiquan Li, Zhigang Zhang, Mengke Niu, Jing Fei, Jiaojiao Zhang, Jianwei Zhou, Kongming Wu, Ming Yi, Tianye Li   +9 more
wiley   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha ( Withania somnifera )

Phytotherapy Research, Volume 40, Issue 8, Page 5030-5047, August 2026.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

STUDY OF STABILITY OF CELL CARRIERS AND CELLULAR FORMS OF VINKRISTIN AND VINBLASTIN IN STORAGE

Разработка и регистрация лекарственных средств, 2019
Employees of the department of pharmaceutical chemistry and phar-maceutical technology received modified forms of terpene-indole alkaloids (TIA) - vincristine (VCR) and vinblastine (VBL) known in the therapy of oncological diseases by incorporating them ...
O. V. Trineeva, A. J. Halahakoon
doaj  

Reproductive outcomes in women with Hodgkin's lymphoma in a Danish fertility preservation cohort

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1587-1596, August 2026.
The risk of premature ovarian insufficiency increases with the intensity of alkylating chemotherapy. In general, fertility outcomes were favorable, but chances of live birth decreased with increased intensity of alkylating chemotherapy. Ovarian tissue transplantation enabled natural conception in women with premature ovarian insufficiency, supporting ...
Lotte Berdiin Colmorn, Elisabeth C. Larsen, Anette Tønnes Pedersen, Stine Gry Kristensen, Kirsten Tryde Macklon   +4 more
wiley   +1 more source

Clinical complete response as a surrogate for pathological response in bladder cancer: a systematic review and meta‐analysis

BJU International, Volume 138, Issue 2, Page 186-195, August 2026.
Objective To evaluate the concordance between clinical complete response (cCR) and pathological complete response (pCR) in muscle‐invasive bladder cancer (MIBC) to assess the surrogacy and prognostic value of cCR for guiding bladder‐sparing strategies.
Navid Roessler, Marcin Miszczyk, Paolo Gontero, Alessandro Dematteis, Keiichiro Miyajima, Shota Inoue, Katharina Oberneder, Markus von Deimling, Victor M. Schuettfort, Malte W. Vetterlein, Bernadett Szabados, Pawel Rajwa, Pierre I. Karakiewicz, Jeremy Yuen‐Chun Teoh, Margit Fisch, Shahrokh F. Shariat   +15 more
wiley   +1 more source

The impact of ERBB2 alterations in muscle‐invasive bladder cancer after neoadjuvant chemotherapy

BJUI Compass, Volume 7, Issue 8, August 2026.
Earle F. Burgess, Hilary Elom, Landon C. Brown, Michael McCormack, Ericson Stoen, Metamia Ciampricotti, Edward Williams, James T. Symanowski   +7 more
wiley   +1 more source

Vinca Alkaloids

International Journal of Preventive Medicine, 2013
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects.
Maryam Moudi, Rusea Go, Christina Yong Seok Yien, Mohd Nazre   +3 more
doaj  

Molecular Characterization of Ovarian Yolk Sac Tumor in a Postmenopausal Woman: Implications for Pathogenesis

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 8, August 2026.
ABSTRACT Ovarian yolk sac tumor is a rare malignant germ cell tumor that typically occurs in young women. In postmenopausal women, yolk sac tumors are extremely rare and have a poor prognosis. These tumors may arise from different biological mechanisms, as germ cells are absent in postmenopausal ovaries.
Mihiro Dejima, Minoru Nagashima, Mamiko Onuki, Miki Kushima, Akihiko Sekizawa, Koji Matsumoto   +5 more
wiley   +1 more source

Selumetinib as a Target Therapy in Progressive Paediatric Low‐Grade Gliomas—Case Series (pLGG)

Journal of Paediatrics and Child Health, Volume 62, Issue 8, Page 1499-1508, August 2026.
ABSTRACT Background Optic pathway gliomas (OPGs) occur in 15%–20% of children with neurofibromatosis type 1 (NF1). While smaller gliomas may be only monitored, the current standard of care for symptomatic ones relies on chemotherapy, most commonly carboplatin and vincristine.
Laura Trapani, Giulia Gortani, Andrea Magnolato, Flora Maria Murru, Elisabetta Cattaruzzi, Laura Diplotti, Paola Michieletto, Silvia Giganti, Davide Zanon, Alessandra Maestro, Valentina Kiren, Egidio Barbi, Irene Bruno   +12 more
wiley   +1 more source