Results 11 to 20 of about 9,166 (164)

Inadvertent intrathecal application of vindesine and its neurological outcome: case report and systematic review of the literature [PDF]

Brain and Spine
Introduction: Vinca alkaloids are used to treat a diversity of malignancies. Inadvertent intrathecal application is followed by severe neurological consequences, with fatal outcomes in the majority of the reported cases.
A. Babaee, H. Yasin, B. Berger, M. Simon
doaj   +2 more sources

Vinca alkaloids as a potential cancer therapeutics: recent update and future challenges [PDF]

3 Biotech, 2023
Shubham Tiwari, Pradeep Kumar, Tiwari Shubham   +2 more
exaly   +2 more sources

Negative-Pressure Cavitation Extraction of Four Main Vinca Alkaloids from <em>Catharanthus </em><em>r</em><em>oseus</em> Leaves [PDF]

Molecules, 2012
In the present study, an improved method termed negative-pressure cavitation extraction (NPCE) followed by reverse phase high-performance liquid chromatography (RP-HPLC) was developed for the extraction and quantification of vindoline (VDL ...
Yuangang Zu, Xiaorui Guo, Yujie Fu, Meng Luo, Wei Wang, Liuqing Yang, Fansong Mu   +6 more
doaj   +2 more sources

Cardiotoxic Effects of Yew Tree and Pink Periwinkle Alkaloids

Безопасность и риск фармакотерапии, 2021
Antitumour herbal medicines based on pink periwinkle and yew tree alkaloids are included in combination therapies for many types of cancer. The use of these classes of products may entail cardiotoxic effects leading to life-threatening conditions.
G. S. Mal, E. B. Artyushkova, M. P. Gladchenko, A. A. Ivanova   +3 more
doaj   +1 more source

P061 (0125) CHEMOTHERAPY-INDUCED POLYNEUROPATHY IN PATIENTS WITH HODGKIN LYMPHOMA TREATED WITH VINCA-ALKALOIDS [PDF]

HemaSphere, 2018
doaj   +2 more sources

Larvicidal Effect of Vinca Fruit Extract (Vinca rosea) Against Aedes aegypti Larvae and Secondary Metabolites Profile by Thin Layer Chromatography

Biology, Medicine & Natural Product Chemistry, 2014
Background: Vinca rosea is known contain alkaloids, it was usually used to treat various diseases. Alkaloids from Vinca leaves are also already known have larvicidal activity. Based on this toxicological activity, the fruit of Vinca rosea was selected to
Rahmawati Ekaputri, Sudarsono Sudarsono, Budi Mulyaningsih   +2 more
doaj   +1 more source

Determination of Active Ingredients, Mineral Composition and Antioxidant Properties of Hydroalcoholic Macerates of Vinca minor L. Plant from the Dobrogea Area

Molecules, 2023
In recent decades, new alternative therapies using drugs containing active ingredients of natural origin have been a hot topic for medical research. Based on the confirmed therapeutic potential of the Vinca minor plant, considered in the specialized ...
Ana-Maria Neculai, Gabriela Stanciu, Magdalena Mititelu   +2 more
doaj   +1 more source

Indole Alkaloids from and Growing in Turkey

Natural Product Communications, 2012
A new indole alkaloid, 11-hydroxypolyneuridine, was isolated from Vinca major subsp. major L. and the known indole alkaloids vallesiachotamine and isovallesiachotamine from Vinca minor L.
Fatemeh Bahadori, Gülaçtι Topçu, Mehmet Boǧa, Ayla Türkekul, Ufuk Kolak, Murat Kartal   +5 more
doaj   +1 more source

Biosynthesis and Modulation of Terpenoid Indole Alkaloids in Catharanthus roseus: A Review of Targeting Genes and Secondary Metabolites

Journal of Pure and Applied Microbiology, 2021
The medicinal plant C. roseus synthesizes biologically active alkaloids via the terpenoid indole alkaloid (TIAs) biosynthetic pathway. Most of these alkaloids have high therapeutic value, such as vinblastine and vincristine.
Mukesh Kumar Sharma, Mohan Kumar, Renu
doaj   +1 more source

Comparative study of the radiosensitising and cell cycle effects of vinflunine and vinorelbine, in vitro

BMC Cancer, 2008
Background Vinca alkaloids are an important class of anticancer agents and semisynthetic vinca alkaloids are developed to improve the therapeutic index of this class of drugs.
Pattyn Greet GO, Lambrechts Hilde AJ, De Pooter Christel MJ, Pauwels Bea, Lardon Filip, Simoens Cindy, Breillout Fabienne, Vermorken Jan B   +7 more
doaj   +1 more source