Larvicidal Effect of Vinca Fruit Extract (Vinca rosea) Against Aedes aegypti Larvae and Secondary Metabolites Profile by Thin Layer Chromatography [PDF]
Biology, Medicine & Natural Product Chemistry, 2014 Background: Vinca rosea is known contain alkaloids, it was usually used to treat various diseases. Alkaloids from Vinca leaves are also already known have larvicidal activity. Based on this toxicological activity, the fruit of Vinca rosea was selected to
Rahmawati Ekaputri +2 more
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Inadvertent intrathecal application of vindesine and its neurological outcome: case report and systematic review of the literature [PDF]
Brain and SpineIntroduction: Vinca alkaloids are used to treat a diversity of malignancies. Inadvertent intrathecal application is followed by severe neurological consequences, with fatal outcomes in the majority of the reported cases.
A. Babaee, H. Yasin, B. Berger, M. Simon
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Beyond the Paclitaxel and Vinca Alkaloids: Next Generation of Plant-Derived Microtubule-Targeting Agents with Potential Anticancer Activity. [PDF]
Cancers (Basel), 2020 Plants are an important source of chemically diverse natural products that target microtubules, one of the most successful targets in cancer therapy. Colchicine, paclitaxel, and vinca alkaloids are the earliest plant-derived microtubule-targeting agents (
Zhang D, Kanakkanthara A.
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Resistance to anti-tubulin agents: From vinca alkaloids to epothilones. [PDF]
Cancer Drug Resist, 2019 This review describes the mechanism of action - inhibition of microtubules - and the most important mechanisms of resistance for vinca alkaloids, taxanes and epothilones.
Krause W.
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Cardiotoxic Effects of Yew Tree and Pink Periwinkle Alkaloids
Безопасность и риск фармакотерапии, 2021 Antitumour herbal medicines based on pink periwinkle and yew tree alkaloids are included in combination therapies for many types of cancer. The use of these classes of products may entail cardiotoxic effects leading to life-threatening conditions.
G. S. Mal +3 more
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ON SOME PHARMACOLOGICAL PROPERТIES OF ТНЕ ALKALOIDS OF VINCA MAJOR [PDF]
, 1964 Pharmacological studies of the alkaloids of Vinca minor and Vinca hеrbасеае revealed that compounds found in these plants аrе highly active pharmacologic agents.
Jelyazkov, D. K., Uzunov, P. D.
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P061 (0125) CHEMOTHERAPY-INDUCED POLYNEUROPATHY IN PATIENTS WITH HODGKIN LYMPHOMA TREATED WITH VINCA-ALKALOIDS [PDF]
HemaSphere, 2018 doaj +2 more sources
Molecules, 2023 In recent decades, new alternative therapies using drugs containing active ingredients of natural origin have been a hot topic for medical research. Based on the confirmed therapeutic potential of the Vinca minor plant, considered in the specialized ...
Ana-Maria Neculai +2 more
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Indole Alkaloids from and Growing in Turkey
Natural Product Communications, 2012 A new indole alkaloid, 11-hydroxypolyneuridine, was isolated from Vinca major subsp. major L. and the known indole alkaloids vallesiachotamine and isovallesiachotamine from Vinca minor L.
Fatemeh Bahadori +5 more
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Journal of Pure and Applied Microbiology, 2021 The medicinal plant C. roseus synthesizes biologically active alkaloids via the terpenoid indole alkaloid (TIAs) biosynthetic pathway. Most of these alkaloids have high therapeutic value, such as vinblastine and vincristine.
Mukesh Kumar Sharma, Mohan Kumar, Renu
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