Results 81 to 90 of about 2,672,670 (309)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Concurrent Circulation of Viral Agents in Pediatric Patients Presenting with Respiratory Illness and Diarrheal Symptoms in Metropolitan Region of São Paulo, Brazil, 2021

open access: yesViruses
Pneumonia and diarrhea are the leading causes of death in children under 5 globally, worsened by viral infections. This study investigates viral agents in children ≤ 3 years with respiratory illness and diarrhea in Metropolitan Region of São Paulo ...
Adriana Luchs   +15 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Viral diversity of Junín virus field strains

open access: yesVirus Research, 2011
The Argentine Hemorrhagic Fever, an endemic disease present in a much of Argentina, is caused by the Junín virus (JUNV). Currently, there are sequences available from several strains of this virus, like those belonging to the vaccine lineage (XJ13, XJ#44 and Candid#1), as well as MC2 (rodent isolate) and IV4454 (human isolate).
Goñi, Sandra Elizabeth   +5 more
openaire   +3 more sources

The diversity of endogenous viral elements in insects

open access: yesCurrent Opinion in Insect Science, 2022
We provide an overview of the currently known diversity of viral sequences integrated into insect genomes. Such endogenous viral elements (EVE) have so far been annotated in at least eight insect orders and can be assigned to at least three families of large double-stranded (ds) DNA viruses, at least 22 families of RNA viruses, and three families of ...
Gilbert, Clément, Belliardo, Carole
openaire   +3 more sources

Evolutionary Diversity of Bat Rabies Virus in São Paulo State, Brazil

open access: yesViruses
The history of the rabies virus dates back four millennia, with the virus being considered by many to be the first known transmitted between animals and humans.
Luzia H. Queiroz   +14 more
doaj   +1 more source

Viral diversity of Rhipicephalus microplus parasitizing cattle in southern Brazil

open access: yesScientific Reports, 2018
Ticks are ectoparasites spread worldwide and are well known as vectors of many viruses of great importance to human and animal health. However, the viral diversity in ticks is still poorly understood, particularly in South America.
W. M. Souza   +11 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Arctic an unexpected hotspot for viral diversity [PDF]

open access: yesNature Reviews Microbiology, 2019
This study reports the findings of a large global survey of the ecological diversity of viruses in the oceans and shows that the Arctic ocean is an unexpected hotspot for viral diversity.
openaire   +2 more sources

Untapped viral diversity in global soil metagenomes

open access: yesbioRxiv, 2019
Viruses outnumber every other biological entity on Earth, and soil viruses are particularly diverse compared to other habitats. However, we have limited understanding of soil viruses because of the tremendous variation in soil ecosystems and because of ...
E. Graham   +7 more
semanticscholar   +1 more source

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