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Viral entry mechanisms: the increasing diversity of paramyxovirus entry [PDF]
The FEBS Journal, 2009 The paramyxovirus family contains established human pathogens such as the measles virus and human respiratory syncytial virus, as well as emerging pathogens including the Hendra and Nipah viruses and the recently identified human metapneumovirus. Two major envelope glycoproteins, the attachment protein and the fusion protein, promote the processes of ...
Everett C, Smith +4 more
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Frontiers in Medicine, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral pathogen causing life-threatening diseases in humans. Interaction between the spike protein of SARS-CoV-2 and angiotensin-converting enzyme 2 (ACE2) is a potential factor in the ...
Manas Ranjan Praharaj +14 more
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Respiratory Syncytial Virus Entry Inhibitors Targeting the F Protein
Viruses, 2013 Human respiratory syncytial virus (RSV) is the main viral cause of respiratory tract infection in infants as well as some elderly and high-risk adults with chronic pulmonary disease and the severely immunocompromised.
Shibo Jiang +3 more
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Caveolin-1 associated adenovirus entry into human corneal cells. [PDF]
PLoS ONE, 2013 The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Mohammad A Yousuf +7 more
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A Mimivirus Enzyme that Participates in Viral Entry [PDF]
Structure, 2015 Mimivirus was initially identified as a bacterium because its dense, 125-nm-long fibers stained Gram-positively. These fibers probably play a role during the infection of some host cells. The normal hosts of Mimivirus are unknown, but in the laboratory Mimivirus is usually propagated in amoeba.
Klose, Thomas +5 more
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Virology Journal, 2018 Background Human enterovirus 71 (EV71) was previously known to enter cells through clathrin or caveolar mediated endocytic pathways. However, we observed chlorpromazine (CPZ) or dynasore (DNS), which inhibit clathrin and dynamin mediated endocytosis, did
Meichun Yuan +10 more
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Statistical Mechanics of Viral Entry
Physical Review Letters, 2015 Viruses that have lipid-membrane envelopes infect cells by fusing with the cell membrane to release viral genes. Membrane fusion is known to be hindered by high kinetic barriers associated with drastic structural rearrangements-yet viral infection, which occurs by fusion, proceeds on remarkably short time scales.
Yaojun, Zhang, Olga K, Dudko
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Viral cell recognition and entry [PDF]
Protein Science, 1994 AbstractRhinovirus infection is initiated by the recognition of a specific cell‐surface receptor. The major group of rhino‐virus serotypes attach to intercellular adhesion molecule‐1 (ICAM‐1). The attachment process initiates a series of conformational changes resulting in the loss of genomic RNA from the virion.
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Viral entry and the ubiquitin‐proteasome system [PDF]
Cellular Microbiology, 2020 Viruses confiscate cellular components of the ubiquitin-proteasome system (UPS) to facilitate many aspects of the infectious cycle. The 26S proteasome is an ATP-dependent, multisubunit proteolytic machine present in all eukaryotic cells. The proteasome executes the controlled degradation of functional proteins, as well as the hydrolysis of aberrantly ...
Seth M. Schneider +2 more
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Ezrin interacts with the SARS coronavirus spike protein and restrains infection at the entry stage [PDF]
, 2012 © 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Béatrice Nal +66 more
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