Signalling in viral entry. [PDF]
Viral infections are serious battles between pathogens and hosts. They can result in cell death, elimination of the virus or latent infection keeping both cells and pathogens alive.
Greber, U F, Greber UF
core +5 more sources
Membranotropic peptides mediating viral entry [PDF]
The means used by enveloped viruses to bypass cellular membranes are well characterized; how- ever, the mechanisms used by non-enveloped viruses to deliver their genome inside the cell remain unresolved and poorly defined.
Galdiero, Stefania +7 more
core +4 more sources
Virus infection of host cells requires that entry into the cell results in efficient genome release leading to translation and replication. These initial steps revolving around the entry and genomic release processes are crucial for viral progeny ...
Saiz Calahorra, Juan Carlos +11 more
core +3 more sources
Disentangling Viral Entry Kinetics Using Lipid Bilayers Coating Silica Nanoparticles [PDF]
Enveloped viruses infect cells via fusion between the viral envelope and a cellular membrane. This membrane fusion process is driven by viral proteins, but slow stochastic protein activation dominates fusion kinetics, making it challenging
Ana M., Villamil Giraldo, Peter, Kasson
core +1 more source
The Evolving Role of Zika Virus Envelope Protein in Viral Entry and Pathogenesis. [PDF]
Zika virus (ZIKV) was first discovered in Uganda’s Zika Forest in 1947. The early African viruses posed little or no health risk to humans. Since then, ZIKV has undergone extensive genetic evolution and adapted to humans, and it now causes a range ...
Roozitalab A +4 more
europepmc +2 more sources
Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick +38 more
core +1 more source
Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry [PDF]
Emerging viral diseases pose a threat to the global population as intervention strategies are mainly limited to basic containment due to the lack of efficacious and approved vaccines and antiviral drugs.
Temperton, Nigel J. +24 more
core +1 more source
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu +16 more
core +1 more source
The Antisense Protein ASP of HIV-1 Enhances Viral Entry in CD4+ T Cells. [PDF]
International audienceThe negative strand of the human immunodeficiency virus-1 (HIV-1) proviral genome contains an antisense open reading frame encoding a protein (ASP) with no known homologs.
Houmey MA +6 more
europepmc +2 more sources
Non-viral approaches to gene therapy [PDF]
Several advances in non-viral gene transfer technology have been reported over the past year. Cationic lipids have been successfully used to deliver genes in vivo, providing a clear alternative to recombinant viruses.
Wagner, Ernst, Cotten, Matt
core +1 more source

