Results 111 to 120 of about 254,896 (222)

Picornavirus 2C proteins: structure-function relationships and interactions with host factors

Frontiers in Cellular and Infection Microbiology
Picornaviruses, which are positive-stranded, non-enveloped RNA viruses, are known to infect people and animals with a broad spectrum of diseases. Among the nonstructural proteins in picornaviruses, 2C proteins are highly conserved and exhibit multiple ...
Chunhui Yin, Chunhui Yin, Chunhui Yin, Haomiao Zhao, Haomiao Zhao, Haomiao Zhao, Xiaoyi Xia, Xiaoyi Xia, Zhengyang Pan, Zhengyang Pan, Daoqun Li, Daoqun Li, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +14 more
doaj   +1 more source

Putative Fusion-Associated Small Transmembrane (FAST) Proteins Encoded by Viruses of Pistolviridae, Order Ghabrivirales, Identified from In Silico Analyses

Viruses
Fusion-associated small transmembrane (FAST) proteins are viral nonstructural proteins known to be encoded by specific members of the Spinareoviridae, specifically within the Aquareovirus and Orthoreovirus genera.
Racheal Amono, Turhan Markussen, Øystein Evensen, Aase B. Mikalsen   +3 more
doaj   +1 more source

Interactions between Viral Nonstructural Proteins and Host Protein hVAP-33 Mediate the Formation of Hepatitis C Virus RNA Replication Complex on Lipid Raft

Journal of Virology, 2004
Lu Gao, H. Aizaki, Jian‐Wen He, M. Lai
semanticscholar   +1 more source

Use of Confocal Immunofluorescence Microscopy To Localize Viral Nonstructural Proteins and Potential Sites of Replication in Pigs Experimentally Infected with Foot-and-Mouth Disease Virus

Journal of Virology, 2005
P. Monaghan, Jennifer L. Simpson, C. Murphy, S. Durand, Melvyn Quan, Soren Alexandersen   +5 more
semanticscholar   +1 more source

Identification of viral protease-dependent cleavage sites within the human astrovirus polyprotein

Journal of Virology
Infection by human astrovirus (HAstV), a small, positive-strand RNA virus, is a major cause of gastroenteritis and has been implicated in an increasing number of severe, sometimes fatal, neurological diseases since 2008.
Samaneh Mehri, Brooke Bengert, Madeline Holliday, Lochlain Corliss, Peter E. Prevelige, Nicholas J. Lennemann   +5 more
doaj   +1 more source

STT3A-mediated mega protein complex assembly during dengue and Zika virus infection

iScience
Summary: Flavivirus replication in mammalian cells requires host oligosaccharyltransferase (OST) complex, which is classically known to catalyze protein N-glycosylation. However, enzymatic activity of OST is not required for flavivirus infection, leaving
Tao Liu, Natasha W. Hanners, Huangheng Tao, Claudia Szabo, Dao Xu, Wei Lin, John W. Schoggins, Nan Yan, Jianjun Wu   +8 more
doaj   +1 more source

Heat shock protein 70 enhances viral replication by stabilizing Senecavirus A nonstructural proteins L and 3D

Veterinary Research
AbstractSenecavirus A (SVA) is an emerging pathogen that causes idiopathic vesicular infections in pig herds, posing a potential threat to their production performance. Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in host homeostasis under both physiological and stress conditions.
Lei Hou, Penghui Zeng, Zhi Wu, Xiaoyu Yang, Jinshuo Guo, Yongyan Shi, Jiangwei Song, Jianwei Zhou, Jue Liu   +8 more
openaire   +3 more sources

Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1

Nature Communications
Cytoskeleton is extensively recruited by flaviviruses for their infection. In this study, we uncovered an essential role of a nuclear membrane protein, SAD1/UNC84 domain protein 2 (SUN2) linking cytoskeleton and nucleoskeleton in the flavivirus ...
Yanxia Huang, Qinyu Peng, Xu Tian, Cancan Chen, Xuanfeng Zhu, Changbai Huang, Zhiting Huo, Yang Liu, Chao Yang, Chao Liu, Ping Zhang   +10 more
doaj   +1 more source

Nonstructural Protein NP1 of Human Bocavirus 1 Plays a Critical Role in the Expression of Viral Capsid Proteins

Journal of Virology, 2016
W. Zou, Fang Cheng, Weiran Shen, J. Engelhardt, Ziying Yan, J. Qiu   +5 more
semanticscholar   +1 more source

Interaction of rotavirus nonstructural protein NSP5 with the viral replication complex

, 2008
Rotavirus morphogenesis starts in intracellular inclusion bodies called viroplasms, where synthesis of the11 dsRNA genome segments and their packaging in new viral particles take place. RNA replication is mediated by several viral proteins, of which VP1, the RNA-dependent RNA polymerase, and VP2, the core scaffolding protein, were shown to be ...
openaire   +1 more source