Results 81 to 90 of about 254,896 (222)

Production of HIV particles is regulated by altering sub-cellular localization and dynamics of Rev induced by double-strand RNA binding protein. [PDF]

PLoS ONE, 2011
Human immunodeficiency virus (HIV)-1 encoded Rev is essential for export from the nucleus to the cytoplasm, of unspliced and singly spliced transcripts coding for structural and nonstructural viral proteins.
Silvio Urcuqui-Inchima, Claudia Patiño, Ximena Zapata, María Patricia García, José Arteaga, Christophe Chamot, Ajit Kumar, Danièle Hernandez-Verdun   +7 more
doaj   +1 more source

Complementation of a Deletion in the Rubella Virus P150 Nonstructural Protein by the Viral Capsid Protein [PDF]

Journal of Virology, 2003
ABSTRACT Rubella virus (RUB) replicons with an in-frame deletion of 507 nucleotides between two Not I sites in the P150 nonstructural protein (Δ Not I) do not replicate (as detected by expression of a reporter gene encoded by the replicon) but can be amplified by wild-type helper ...
Wen-Pin, Tzeng, Teryl K, Frey
openaire   +2 more sources

Biodegradable, Breathable, and Skin‐Friendly Solution‐Blown Quercetin Nanofibers for Antiviral Nonwoven Filter

EcoMat, Volume 8, Issue 4, April 2026.
A nanofiber filter of quercetin and poly(ethylene oxide), produced through a solution‐blowing technique, serves as an eco‐friendly, high‐performance alternative for antiviral mask filters. The resulting material combines effective particle filtration with excellent breathability, robust mechanical strength, and rapid biodegradability, while also ...
Dogun Park, Joo‐Hyun Hong, Zijun Li, Yeongtak Son, Yea Jung Choi, Sullim Lee, Hyun‐Woo Kim, Daekyu Choi, Kiyong Kim, Yun Seok Joh, Do‐Kyun Kim, Hee Min Yoo, Ki Hyun Kim, Seongpil An   +13 more
wiley   +1 more source

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins.

PLoS Pathogens, 2022
Autonomous parvoviruses encode at least two nonstructural proteins, NS1 and NS2. While NS1 is linked to important nuclear processes required for viral replication, much less is known about the role of NS2. Specifically, the function of canine parvovirus (
Salla Mattola, Kari Salokas, Vesa Aho, Elina Mäntylä, Sami Salminen, Satu Hakanen, Einari A Niskanen, Julija Svirskaite, Teemu O Ihalainen, Kari J Airenne, Minna Kaikkonen-Määttä, Colin R Parrish, Markku Varjosalo, Maija Vihinen-Ranta   +13 more
doaj   +1 more source

Functions of Chikungunya Virus Nonstructural Proteins

Chikungunya Virus, 2016
The nonstructural proteins (nsPs) of chikungunya virus (CHIKV) are expressed as one or two polyprotein precursors, which are translated directly from the viral genomic RNA. Mature nsPs are generated by precise processing of these polyproteins.
T. Ahola, A. Merits
semanticscholar   +1 more source

Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication [PDF]

Proceedings of the National Academy of Sciences, 2004
The study of the hepatitis C virus (HCV) has been hindered by the lack of in vitro model systems. The recent development of HCV subgenomic RNA replicons has permitted the study of viral RNA replication in cell culture; however, the requirements for efficient replication of replicons in this system are poorly ...
Matthew J, Evans, Charles M, Rice, Stephen P, Goff   +2 more
openaire   +2 more sources

Whole‐Genome Characterization of Rare Artiodactyl‐Like G10P [14] and G8P [14] Rotavirus A Strains Detected in Pediatric Gastroenteritis Cases in Hokkaido Prefecture, Japan

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Rotavirus alphagastroenteritidis (RVA) is the leading cause of acute gastroenteritis in young children worldwide, as well as in a wide range of animal species. In 2020 and 2022, we identified three unusual RVA strains in pediatric gastroenteritis patients in Hokkaido Prefecture, Japan, using next‐generation sequencing: one G10P[14] strain ...
Akira Takebayashi, Yuya Fukuda, Yoshiki Fujii, Hiroshi Nihira, Minako Kihara, Yoshimasa Kudou, Shuhei Adachi, Noritaka Shintani, Takeshi Tsugawa   +8 more
wiley   +1 more source

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway.

PLoS Pathogens, 2015
Chikungunya virus (CHIKV), the causative agent of a major epidemic spanning five continents, is a positive stranded mRNA virus that replicates using the cell's cap-dependent translation machinery.
Pierre-Emmanuel Joubert, Kenneth Stapleford, Florence Guivel-Benhassine, Marco Vignuzzi, Olivier Schwartz, Matthew L Albert   +5 more
doaj   +1 more source

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

Msphere, 2017
Coronavirus (CoV) emergence in both humans and livestock represents a significant threat to global public health, as evidenced by the sudden emergence of severe acute respiratory syndrome CoV (SARS-CoV), MERS-CoV, porcine epidemic diarrhea virus, and ...
Vineet D. Menachery, Lisa E. Gralinski, H. Mitchell, K. Dinnon, S. Leist, B. Yount, Rachel L. Graham, Eileen T. McAnarney, K. Stratton, A. Cockrell, K. Debbink, A. Sims, K. Waters, R. Baric   +13 more
semanticscholar   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source