ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Targeting endolysosomal acidification inhibits poxvirus entry and replication. [PDF]
Xu S +10 more
europepmc +1 more source
ABSTRACT Objective To analyse sex differences in health‐related quality of life (HRQL) before, during and up to 3 months posttreatment of head and neck cancer, and to examine the importance of salivary secretion rate for HRQL posttreatment. Methods Patients were recruited before starting curative oncologic treatment.
Niklas Bohm +4 more
wiley +1 more source
Importin α1 contributes to Venezuelan equine encephalitis virus-induced cell death, but is not required for the capsid-mediated blockage of nucleocytoplasmic trafficking. [PDF]
Jamiu AT +10 more
europepmc +1 more source
ABSTRACT Aim To evaluate an interprofessional learning (IPL) session involving dental hygiene students and nursing students and to investigate the nursing students' oral health‐related knowledge and attitudes. Material and Method First, a questionnaire about knowledge and attitudes regarding oral health was answered by 84 nursing students. After an IPL
Annica Almståhl +2 more
wiley +1 more source
Inhibition of dengue virus type 2 by hypericin mediated through viral envelope protein interaction. [PDF]
Qi L +6 more
europepmc +1 more source
Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev +5 more
wiley +1 more source
Establishment of a green fluorescent protein (GFP)-based reporter for picornaviral 3C proteases. [PDF]
Hirano J +8 more
europepmc +1 more source
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]
Diamond, Michael S +3 more
core +1 more source

