Results 11 to 20 of about 84,952 (272)
Iranian Journal of Microbiology, 2022 Background and Objectives: SARS-CoV-2 variants of concern (VOC) and interest (VOI) pose a significant threat to public health because the rapid change in the SARS-CoV-2 genome can alter viral phenotypes such as virulence, transmissibility and the ...
Maria Isabel Zapata-Cardona +8 more
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Dynamic Model Visualizing the Process of Viral Plaque Formation
Journal of Microbiology & Biology Education, 2012 In Microbiology and Virology courses, viral plaques are often presented to students as the way one can visualize viruses/bacteriophages. While students generally grasp the idea that counting plaques is essentially the same as counting viruses in their ...
Boriana Marintcheva
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Plaques Formed by Mutagenized Viral Populations Have Elevated Coinfection Frequencies
mBio, 2017 The plaque assay is a common technique used to measure virus concentrations and is based upon the principle that each plaque represents a single infectious unit.
Elizabeth R. Aguilera +4 more
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Improved Zika virus plaque assay using Vero/TMPRSS2 cell line
Microbiology SpectrumPlaque assay is the gold standard for the quantification of viable cytopathic viruses like Zika virus (ZIKV). Some strains of ZIKV produce plaques that are very difficult to accurately visualize and count on the commonly used Vero cell line.
Olukunle O. Oluwasemowo +3 more
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Machine-learning-based automated quantification machine for virus plaque assay counting [PDF]
PeerJ Computer Science, 2022 The plaque assay is a standard quantification system in virology for verifying infectious particles. One of the complex steps of plaque assay is the counting of the number of viral plaques in multiwell plates to study and evaluate viruses.
Gridsada Phanomchoeng +6 more
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Identification and characterisation of SARS-CoV-2 and Human alphaherpesvirus 1 from a productive coinfection in a fatal COVID-19 case [PDF]
Memorias do Instituto Oswaldo Cruz, 2022 BACKGROUND During routine Coronavirus disease 2019 (COVID-19) diagnosis, an unusually high viral load was detected by reverse transcription real-time polymerase chain reaction (RT-qPCR) in a nasopharyngeal swab sample collected from a patient with ...
Alice Laschuk Herlinger +20 more
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Accelerated and improved quantification of lymphocytic choriomeningitis virus (LCMV) titers by flow cytometry. [PDF]
PLoS ONE, 2012 Lymphocytic choriomeningitis virus (LCMV), a natural murine pathogen, is a member of the Arenavirus family, may cause atypical meningitis in humans, and has been utilized extensively as a model pathogen for the study of virus-induced disease and immune ...
Darlynn Korns Johnson, Dirk Homann
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Biomedicines, 2021 Engineered vaccinia virus (VACV) strains are used extensively as vectors for the development of novel cancer vaccines and cancer therapeutics. In this study, we describe for the first time a high-throughput approach for both fluorescent rVACV generation ...
Mingyu Ye +3 more
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SARS-CoV-2 coinfection in immunocompromised host leads to the generation of recombinant strain
International Journal of Infectious Diseases, 2023 Objectives: Recombination related to coinfection is a huge driving force in determining the virus genetic variability, particularly in conditions of partial immune control, leading to prolonged infection.
Silvia Zannoli +13 more
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SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virus
Frontiers in Immunology, 2023 Despite recent advances in the research on oncolytic viruses (OVs), a better understanding of how to enhance their replication is key to improving their therapeutic index.
Almohanad A. Alkayyal +21 more
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