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BMC Infectious Diseases, 2020 Background The polymerase chain reaction (PCR) is commonly used to detect viral pathogens because of its high sensitivity and specificity. However, conventional PCR methods cannot determine virus infectivity.
Yuki Nakaya +4 more
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Increases of Corporal Temperature as a Risk Factor of Atherosclerotic Plaque Instability [PDF]
, 2008 This work explores for the first time the effects of temperature increments on the development of high shear stresses between plaque and arterial wall due to their different dilatational properties. Data from the literature report febrile reactions prior
Rojo Pérez, Francisco Javier +9 more
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Virucidal and Neutralizing Activity Tests for Antiviral Substances and Antibodies
Bio-Protocol, 2018 In a narrow definition, virucidal activity represents the activity by which to interact with and physically disrupt viral particles. In a broad definition, it includes the activity by which to functionally inhibit (neutralize) viral infectivity without ...
Chie Aoki-Utsubo, Ming Chen, Hak Hotta
doaj +1 more source
Iranian Journal of Microbiology, 2022 Background and Objectives: SARS-CoV-2 variants of concern (VOC) and interest (VOI) pose a significant threat to public health because the rapid change in the SARS-CoV-2 genome can alter viral phenotypes such as virulence, transmissibility and the ...
Maria Isabel Zapata-Cardona +8 more
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Peptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection. [PDF]
PLoS ONE, 2013 BACKGROUND: Feline infectious peritonitis (FIP) is a lethal immune-mediated disease caused by feline coronavirus (FCoV). Currently, no therapy with proven efficacy is available.
I-Jung Liu +3 more
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ViralPlaque: a Fiji macro for automated assessment of viral plaque statistics [PDF]
PeerJ, 2019 Plaque assay has been used for a long time to determine infectious titers and characterize prokaryotic and eukaryotic viruses forming plaques. Indeed, plaque morphology and dimensions can provide information regarding the replication kinetics and the ...
Marco Cacciabue +2 more
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Antiviral activity of recombinant porcine interferon-α against porcine transmissible gastroenteritis virus in pk-15 cells [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 A recombinant porcine interferon alpha (rPoIFN-α) has been developed and patented previously (Chinese patent number ZL200810020180.4). In the current study, we investigated the inhibitory effects of the rPoIFN-α on the propagation of porcine ...
ZHAO J +8 more
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Animals, 2023 Iron flocculation is widely used to concentrate viruses in water, followed by Fe-virus flocculate formation, collection, and elution. In the elution stage, an oxalic or ascorbic acid re-suspension buffer dissolved iron hydroxide.
Na-Gyeong Ryu +3 more
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Infectious Focus Assays and Multiplicity of Infection (MOI) Calculations for Alpha-herpesviruses
Bio-Protocol, 2014 Titration of viral stocks is a critical process before any experimental use of the virus. Here we describe an infectious focus assay for several alphaherpesviruses, a titration method for fluorescently labeled viruses, based on the original plaque assay.
Anna Sloutskin, Ronald Goldstein
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Suramin Inhibits Chikungunya Virus Entry and Transmission. [PDF]
PLoS ONE, 2015 The mosquito-borne Chikungunya virus (CHIKV) is a profound global threat due to its high rate of contagion and the lack of vaccine or effective treatment.
Yi-Jung Ho +6 more
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