Results 41 to 50 of about 1,527,964 (244)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Real-time PCR provides improved detection and titer determination of bacteriophage

BioTechniques, 2003
The plaque assay is the traditional method for the quantification of bacteriophage, particularly for λ cloning vectors. Unfortunately, this technique is fraught with procedural difficulties, and the quality of the data obtained from this “gold standard ...
Daniel C. Edelman, Janet Barletta
doaj   +1 more source

Estudo da incidência de adenovírus humano e suíno, norovírus humano e circovírus suíno, em amostras de água de consumo e descedentação animal do município de Concórdia, Santa Catarina [PDF]

, 2011
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Os dejetos provenientes da suinocultura e da população podem potencialmente contaminar mananciais de captação de água para consumo, já que esses efluentes ...
Garcia, Lucas Ariel Totaro
core  

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Quantification of Infectious Sendai Virus Using Plaque Assay

Bio-Protocol, 2018
Sendai virus (SeV) is an enveloped, single-stranded RNA virus of the family Paramyxoviridae. SeV is a useful tool to study its infectious pathomechanism in immunology and the pathomechanism of a murine model of IgA nephropathy.
Narihito Tatsumoto, Takamasa Miyauchi, Moshe Arditi, Michifumi Yamashita   +3 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Correlation between herpes simplex virus neutralizing antibody titers determined by ELVIS cell and traditional plaque reduction assays.

PLoS ONE, 2019
Preventive viral vaccine efficacy trials require large-scale sample analysis to quantitate immune responses and their correlation with infection outcomes.
Tamara P Blevins, Yinyi Yu, Robert B Belshe, Abbie R Bellamy, Lynda A Morrison   +4 more
doaj   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Virucidal activity of Colombian Lippia essential oils on dengue virus replication in vitro

Memorias do Instituto Oswaldo Cruz, 2010
The inhibitory effect of Lippia alba and Lippia citriodora essential oils on dengue virus serotypes replication in vitro was investigated. The cytotoxicity (CC50) was evaluated by the MTT assay and the mode of viral inhibitory effect was investigated ...
Raquel Elvira Ocazionez, Rocio Meneses, Flor Ángela Torres, Elena Stashenko   +3 more
doaj   +1 more source

Population dynamics of SNJ1 determined by plaque assay and qPCR.

, 2016
The cells of Natrinema sp. J7-2 were infected by halovirus SNJ1 with an MOI of 50 for 1.5 h, then samples were taken from the culture system at indicated times, and the titers of samples were detected by plaque assay and qPCR.
Ming Yang (109148), Congcong He (719033), Yunjun Mei (719032), Dala Ba (3168687), Shunxi Zhang (3168690), Ping Shen (149355), Wei Deng (17330), Jian Zhang (1682), Xiangdong Chen (149352)   +8 more
core   +1 more source