Results 11 to 20 of about 428,951 (317)
Exploiting Connections for Viral Replication [PDF]
Frontiers in Cell and Developmental Biology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the COVID-19 (coronavirus disease 2019) pandemic, is a positive strand RNA (+RNA) virus. Like other +RNA viruses, SARS-CoV-2 is dependent on host cell metabolic machinery to survive and replicate, remodeling cellular membranes to generate sites of viral replication.
Wong, LH +4 more
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Cooperative nature of viral replication [PDF]
Science Advances, 2020 Group transmission of viruses accelerates early replication and increases short-term viral fitness.
Iván Andreu-Moreno +2 more
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The Role of APOBECs in Viral Replication [PDF]
Microorganisms, 2020 Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) proteins are a diverse and evolutionarily conserved family of cytidine deaminases that provide a variety of functions from tissue-specific gene expression and immunoglobulin diversity to control of viruses and retrotransposons.
Wendy K. Xu +2 more
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Endocytosis in Viral Replication [PDF]
Traffic, 2000 Although initially recognised as essential for the entry of certain viruses, endocytosis is now known to also play important roles in the replication of, and adaptation to, the host cell of a number of viruses. Here we consider several aspects of this association and recent results that have emerged to support this view.
Annegret Pelchen-Matthews, Mark Marsh
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Cytoplasmic Viral Replication Complexes [PDF]
Cell Host & Microbe, 2010 Many viruses that replicate in the cytoplasm compartmentalize their genome replication and transcription in organelle-like structures that enhance replication efficiency and protection from host defenses. In particular, recent studies with diverse positive-strand RNA viruses have further elucidated the ultrastructure of membrane-bound RNA replication ...
Arturo Diaz +2 more
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Autophagy in Viral Replication and Pathogenesis [PDF]
Molecules and Cells, 2010 Autophagy is a catabolic process that is important for the removal of damaged organelles and long-lived proteins for the maintenance of cellular homeostasis. It can also serve as innate immunity to remove intracellular microbial pathogens. A growing list of viruses has been shown to affect this cellular pathway.
Jing-hsiung James Ou, Donna Sir
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Cyclophilins as Modulators of Viral Replication [PDF]
Viruses, 2013 Cyclophilins are peptidyl‐prolyl cis/trans isomerases important in the proper folding of certain proteins. Mounting evidence supports varied roles of cyclophilins, either positive or negative, in the life cycles of diverse viruses, but the nature and mechanisms of these roles are yet to be defined.
Stephen D. Frausto +2 more
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Special Issue: “Viral Replication Complexes” [PDF]
Viruses, 2021 Viruses are extraordinary biological entities that can only thrive as obligate intracellular parasites, exploiting other living cellular components in order to reproduce [...]
Núria Verdaguer, Diego S. Ferrero
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Microtubules in viral replication and transport [PDF]
The Plant Journal, 2013 SummaryViruses use and subvert host cell mechanisms to support their replication and spread between cells, tissues and organisms. Microtubules and associated motor proteins play important roles in these processes in animal systems, and may also play a role in plants.
Eduardo José Peña +4 more
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Enhanced Viral Replication by Cellular Replicative Senescence [PDF]
Immune Network, 2016 Cellular replicative senescence is a major contributing factor to aging and to the development and progression of aging-associated diseases. In this study, we sought to determine viral replication efficiency of influenza virus (IFV) and Varicella Zoster Virus (VZV) infection in senescent cells.
Rak Kyun Seong, Ji Ae Kim, Ok Sarah Shin
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