Results 11 to 20 of about 2,261,873 (405)
Cooperative nature of viral replication [PDF]
Science Advances, 2020 Group transmission of viruses accelerates early replication and increases short-term viral fitness. The ability of viruses to infect their hosts depends on rapid dissemination following transmission.
Iván Andreu-Moreno +2 more
semanticscholar +4 more sources
The Role of APOBECs in Viral Replication [PDF]
Microorganisms, 2020 Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) proteins are a diverse and evolutionarily conserved family of cytidine deaminases that provide a variety of functions from tissue-specific gene expression and immunoglobulin ...
Wendy Kaichun Xu, H. Byun, J. Dudley
semanticscholar +4 more sources
Enhanced Viral Replication by Cellular Replicative Senescence [PDF]
Immune Network, 2016 Cellular replicative senescence is a major contributing factor to aging and to the development and progression of aging-associated diseases. In this study, we sought to determine viral replication efficiency of influenza virus (IFV) and Varicella Zoster ...
Ji-Ae Kim, Rak-Kyun Seong, O. S. Shin
semanticscholar +3 more sources
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication
Cell Discovery, 2021 The newly emerging coronavirus SARS-CoV-2 causes severe lung disease and substantial mortality. How the virus evades host defense for efficient replication is not fully understood.
Zhou-Qin Zheng +4 more
semanticscholar +1 more source
Endocytosis in Viral Replication [PDF]
Traffic, 2000 Although initially recognised as essential for the entry of certain viruses, endocytosis is now known to also play important roles in the replication of, and adaptation to, the host cell of a number of viruses. Here we consider several aspects of this association and recent results that have emerged to support this view.
M, Marsh, A, Pelchen-Matthews
openaire +2 more sources
Exploiting Connections for Viral Replication [PDF]
Frontiers in Cell and Developmental Biology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the COVID-19 (coronavirus disease 2019) pandemic, is a positive strand RNA (+RNA) virus. Like other +RNA viruses, SARS-CoV-2 is dependent on host cell metabolic machinery to survive and replicate, remodeling cellular membranes to generate sites of viral replication.
Wong, LH +4 more
openaire +5 more sources
Influenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication
Virologica Sinica, 2021 Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we observed that influenza A virus (H1N1), a single-stranded, negative-sense RNA virus with an eight ...
Lehao Ren +8 more
semanticscholar +1 more source
Cell Research, 2020 A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started to circulate among humans around December 2019, and it is now widespread as a global pandemic.
Chunlong Ma +10 more
semanticscholar +1 more source
Molecular Therapy: Nucleic Acids, 2023 Gene therapy strategies that effectively inhibit HIV-1 replication are needed to reduce the requirement for lifelong antiviral therapy and potentially achieve a functional cure.
Krista A. Delviks-Frankenberry +5 more
doaj +1 more source
Impact of Nuclear Export Pathway on Cytoplasmic HIV-1 RNA Transport Mechanism and Distribution
mBio, 2020 HIV-1 full-length RNA (referred to as HIV-1 RNA here) serves as the viral genome in virions and as a template for Gag/Gag-Pol translation. We previously showed that HIV-1 RNA, which is exported via the CRM1 pathway, travels in the cytoplasm mainly ...
Jianbo Chen +7 more
doaj +1 more source