Results 271 to 280 of about 617,233 (366)

Studies on the role of the phi X174 gene A protein in phi X174 viral strand synthesis. III. Replication of DNA containing two viral replication origins.

, 1988
G S Goetz, J Hurwitz
openalex   +1 more source

Seneca Valley virus infection exploits DNA damage response to facilitate viral replication. [PDF]

J Virol
Song J, Li Z, Yang J, Ma R, Wang D, Quan R, Wen X, Liu J.   +7 more
europepmc   +1 more source

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Navigating a Fine Balance: Point-Mutant Cheater Viruses Disrupt the Viral Replication Cycle. [PDF]

Mol Biol Evol
Meir M, Kahn A, Farage C, Maoz Y, Harel N, Ben Zvi A, Segev S, Volkov M, Yahud R, Gophna U, Stern A.   +10 more
europepmc   +2 more sources

Cell-intrinsic regulation of HBV RNAs by the nonsense-mediated mRNA decay pathway controls viral replication. [PDF]

iScience
Wada M, Morita C, Ohsaki E, Ueda K.
europepmc   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

The rho subunit of RNA polymerase holoenzyme confers specificity in priming M13 viral DNA replication.

, 1982
Jon M. Kaguni, A Kornberg
openalex   +1 more source

Reduction of microRNA-221 in BVDV infection enhances viral replication by targeting the ATG7-mediated autophagy pathway. [PDF]

Ir Vet J
Chen Z, Wang J, Lu B, Meng W, Zhu Y, Jiang Q, Gao D, Ma Z, Zeng H, Chen J, Liu S, Wang Z, Jia K.   +12 more
europepmc   +1 more source

A Phase‐Separated SR Protein Reprograms Host Pre‐mRNA Splicing to Enhance Disease Susceptibility

Advanced Science, EarlyView.
This study identifies SR30, a splicing factor, as a negative regulator of tomato immunity. During Phytophthora infestans infection, the elevated SR30 forms nuclear condensates to suppress the alternative splicing (AS) of defense‐related genes in a phase separation manner.
Dong Yan, Jie Huang, Fengqi Tian, Haidong Shu, Han Chen, Qian Peng, Hongwei Wu, Jianlong Zhao, Anireddy S. N. Reddy, Gang Li, Yuanchao Wang, Suomeng Dong   +11 more
wiley   +1 more source

Immunosuppression with Cyclophosphamide Does Not Prevent Demyelination or Result in Uncontrolled Viral Replication in Coronavirus SD Infected Mice

, 1984
J. S. Burks, L. D. Jankovsky, P. Licari, I. T. McNally, Maurice C. Kemp   +4 more
openalex   +1 more source