Results 271 to 280 of about 2,155,361 (380)
Advanced Therapeutics, EarlyView.Breast cancer is one of the most prevalent solid tumors in women. Doxorubicin is loaded mesoporous silica nanoparticles, capped with HER2‐specific aptamers, and the particle surface is functionalized with hyaluronidase. This dual‐functionalized nanocarrier system offers a promising solution for the drug resistance by solid tumors.
Murat Kavruk +8 more
wiley +1 more source
TXNIP promotes viral replication by disrupting MAVS-mediated antiviral signaling and serves as a therapeutic target for antiviral therapy. [PDF]
Redox BiolChen R +10 more
europepmc +1 more source
Genetic Engineering Methods in Primary T Cells
Advanced Therapeutics, EarlyView.Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley +1 more source
SFTSV NSs interacts with AGO2 to regulate the RNAi pathway for viral replication. [PDF]
J VirolJavaid N, Jang T-W, Fu Y, Choi Y.
europepmc +1 more source
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Advanced Science, EarlyView.Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk +8 more
wiley +1 more source
Deciphering Viral Replication Dynamics in Feline Infectious Peritonitis: A Quantitative Approach. [PDF]
VirusesBurgener CJ +7 more
europepmc +1 more source
Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma.
, 1981 Regine Kollek, Mehran Goulian
openalex +1 more source
Positive-strand RNA viruses stimulate host phosphatidylcholine synthesis at viral replication sites
Proceedings of the National Academy of Sciences of the United States of America, 2016 Jiantao Zhang +7 more
semanticscholar +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source