Results 91 to 100 of about 145,951 (305)
Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications
Advanced Materials, EarlyView.Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa +14 more
wiley +1 more source
Frontiers in ImmunologyChronic lymphocytic leukaemia (CLL) is a lymphoproliferative disorder of abnormal B-lymphocytes. Due to immune deregulation and therapy-related factors, CLL individuals face increased infection risks, making vaccination a priority.
Clara Sánchez-Menéndez +22 more
doaj +1 more source
Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional Cure
Viruses, 2020 HIV-1 establishes a life-long infection when proviral DNA integrates into the host genome. The provirus can then either actively transcribe RNA or enter a latent state, without viral production.
Luisa Mori, Susana T. Valente
doaj +1 more source
Porcine circovirus 3 is highly prevalent in serum and tissues and may persistently infect wild boar (Sus scrofa scrofa) [PDF]
, 2018 Porcine circovirus 3 (PCV‐3) prevalence has been minimally investigated in wild boar; dynamics of infection and viral tissue distribution are currently unknown.
Cabezón Ponsoda, Óscar +9 more
core +4 more sources
Broadly neutralizing antibodies suppress HIV in the persistent viral reservoir [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance A number of highly potent and broadly neutralizing HIV-specific monoclonal antibodies have recently been isolated from B cells of infected individuals. However, the effects of these antibodies on the persistent viral reservoirs in HIV-infected individuals receiving antiretroviral therapy (ART) are ...
Tae-Wook, Chun +10 more
openaire +2 more sources
Poking Pluripotency: Nanoinjection Into Human iPSCs
Advanced Materials, EarlyView.Nanoinjection into hiPSCs: silicon nanotubes effectively transfect human induced pluripotent stem cells (hiPSCs) with mRNA, enabled by a delayed extracellular matrix application and enhanced surface functionalization. Nanoinjection is demonstrated with several reporter mRNA, including co‐transfection of mCherry and GFP.
Jann Harberts +5 more
wiley +1 more source
Reservoir host immunology and life history shape virulence evolution in zoonotic viruses.
PLoS Biology, 2023 The management of future pandemic risk requires a better understanding of the mechanisms that determine the virulence of emerging zoonotic viruses.
Cara E Brook +3 more
doaj +1 more source
Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation [PDF]
, 2017 Current antiretroviral therapy (ART) for HIV/AIDS slows disease progression by reducing viral loads and increasing CD4 counts. Yet ART is not curative due to the persistence of CD4+ T-cell proviral reservoirs that chronically resupply active virus ...
Albert, Brice J +8 more
core +2 more sources
Advanced Materials Technologies, EarlyView.Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu +8 more
wiley +1 more source
Zika virus infection in semen: Effect on human reproduction [PDF]
, 2017 Unique among vector-borne flaviviruses, Zika virus can infect testis and male genital tract, can persist in semen for months after symptoms onset, and be sexually transmitted.
Barzon, Luisa +2 more
core +1 more source