Results 91 to 100 of about 1,595,225 (317)
Applications of viral metagenomics in the veterinary field [PDF]
, 2010 Viral metagenomics provide a powerful technology to investigate the viral flora of healthy and sick animals. Using these methodologies, we gain a better understanding in the etiology of diseases, as well as deepen our knowledge into the viruses ...
Blomström, Anne-Lie
core
Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd +118 more
wiley +1 more source
Exploring viral reservoir: The combining approach of cell sorting and droplet digital PCR.
Methods, 2017 Combined antiretroviral therapy (cART) blocks different steps of HIV replication and maintains plasma viral RNA at undetectable levels. The virus can remain in long-living cells and create a reservoir where HIV can restart replicating after cART ...
L. Gibellini +12 more
semanticscholar +1 more source
Deep sea sediments associated with cold seeps are a subsurface reservoir of viral diversity
The ISME Journal, 2020 In marine ecosystems, viruses exert control on the composition and metabolism of microbial communities, influencing overall biogeochemical cycling.
Zexin Li +10 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Effect of the Bystander Proliferation of the Latent Reservoir on the Latent Reservoir and on Plasma Viral Load [PDF]
, 2013 When there is no ongoing viral replication (ɛ = 1) and the minimum activation rate of the latent reservoir is zero (amin = 0). The open circles indicate the decay kinetics of the latent reservoir suggested by Strain et al.
Alan S Perelson (379607) +1 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Frontiers in ImmunologyIntroductionHIV-1 infection may produce a detrimental effect on the immune response. Early start of antiretroviral therapy (ART) is recommended to preserve the integrity of the immune system. In fact, people with HIV (PWH) and normal CD4/CD8 ratio appear
Guiomar Casado-Fernández +25 more
doaj +1 more source
Rapid Seeding of the Viral Reservoir Prior to SIV Viremia in Rhesus Monkeys
Nature, 2014 The viral reservoir represents a critical challenge for human immunodeficiency virus type 1 (HIV-1) eradication strategies. However, it remains unclear when and where the viral reservoir is seeded during acute infection and the extent to which it is ...
J. Whitney +25 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee +9 more
wiley +1 more source