Results 21 to 30 of about 156,575 (279)

HIV-1 Infection of T Cells and Macrophages Are Differentially Modulated by Virion-Associated Hck: A Nef-Dependent Phenomenon

Viruses, 2013
The proline repeat motif (PxxP) of Nef is required for interaction with the SH3 domains of macrophage-specific Src kinase Hck. However, the implication of this interaction for viral replication and infectivity in macrophages and T lymphocytes remains ...
Gilda Tachedjian, Alison Greenway, Johnson Mak, Alyssa Cornall   +3 more
doaj   +1 more source

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding [PDF]

, 2016
The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target.
Bess, JW, Binet, D, Bouché, L, Canis, K, Chertova, E, Dell, A, Desrosiers, RC, Haslam, SM, Keele, BF, Lifson, JD, Morris, HR, North, SJ, O'Connor, MJ, Pang, PC, Panico, M, Rahman, D   +15 more
core   +1 more source

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G., Briers, Yves, Danis‐Wlodarczyk, Katarzyna, Drulis‐Kawa, Zuzanna, Jang, Ho Bin, Lavigne, Rob, Lood, Cédric, Noben, Jean‐Paul, Noort, Vera, Vandenheuvel, Dieter   +9 more
core   +1 more source

Yeast two hybrid analyses reveal novel binary interactions between human cytomegalovirus-encoded virion proteins. [PDF]

PLoS ONE, 2011
Human cytomegalovirus (HCMV) is the largest human herpesvirus and its virion contains many viral encoded proteins found in the capsid, tegument, and envelope.
Aaron To, Yong Bai, Ao Shen, Hao Gong, Sean Umamoto, Sangwei Lu, Fenyong Liu   +6 more
doaj   +1 more source

Kinetics of acute hepatitis B virus infection in humans [PDF]

, 2001
Using patient data from a unique single source outbreak of hepatitis B virus (HBV) infection, we have characterized the kinetics of acute HBV infection by monitoring viral turnover in the serum during the late incubation and clinical phases of the ...
Brown, D., Dusheiko, G.M., Emery, V.C., Murray, J.M., Perelson, A.S., Webster, G.J.M., Whalley, S.A.   +6 more
core   +1 more source

A nuanced role of the small loop of hepatitis B virus small envelope protein in virion morphogenesis and secretion

Journal of Biomedical Science, 2021
Background The virion secretion mechanism of human hepatitis B virus (HBV) remains to be investigated. In our current study, we characterized a reverse transcriptase mutant, which changed from the YMDD motif to YMHA.
Chih-Hsu Chang, Shu-Fan Chou, Chiaho Shih   +2 more
doaj   +1 more source

HUMAN PARVOVIRUS В19: VIRUS CHARACTERISTICS, DISTRIBUTION AND DIAGNOSTICS OF PARVOVIRUS INFECTION

Инфекция и иммунитет, 2014
. The modern data about morphology as well as structural and functional organization of the parvovirus B19 genome, circulating virus genotypes are presented in the review.
I. N. Lavrentyeva, A. Y. Antipova
doaj   +1 more source

Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity. [PDF]

, 2007
BACKGROUND: Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome.
Andrew ML Lever (60785), Anne L'Hernault (60782), Jane S Greatorex (60783), R Anthony Crowther (60784)   +3 more
core   +3 more sources

MORPHOLOGICAL ANALYSIS OF HEPATITIS B VIRUS WITH ESCAPE MUTATIONS IN S-gene G145R AND S143L

Вопросы вирусологии, 2017
Background. In terms of serological properties and immunization, the wild type of HBsAg HBV and its G145R mutant behave as different antigens. This testifies to serious structural changes, which presumably could have a significant impact on the ...
M. V. Konopleva, M. V. Sokolova, N. V. Shevlyagina, A. I. Bazhenov, A. A. Fel’Dsherova, M. A. Krymskij, V. N. Borisova, T. A. Semenenko, V. G. Nesterenko, A. P. Suslov   +9 more
doaj   +1 more source

Impact of sequence variation in the ul128 locus on production of human cytomegalovirus in fibroblast and epithelial cells [PDF]

, 2013
The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A.
A. J. Davison, Adler, Adler, Akter, Baldanti, Borst, Boyle, Britt, Bronzini, Brunak, Cha, Chan, Chowdary, Compton, Compton, Cunningham, D. J. Dargan, Dargan, Davison, Desmet, Dogan, Dolan, Erice, Feire, Fouts, G. S. Wilkie, Genini, Gerna, Gerna, Grazia Revello, Hahn, Hahn, Haspot, I. Murrell, Irmiere, Isaacson, Isaacson, Jiang, Kari, Kelley, Kinzler, Lilleri, Lopper, Macagno, Magri, Matrosovich, Mocarski, Murphy, O'Connor, P. Tomasec, Paredes, Paterson, Prichard, R. J. Stanton, Rasmussen, Reese, Revello, Ryckman, Ryckman, Ryckman, Saccoccio, Schleiss, Schuessler, Schuessler, Schuessler, Scrivano, Sinclair, Sinzger, Sinzger, Sinzger, Sinzger, Smith, Soroceanu, Stanton, Stanton, Stanton, Stanton, Straschewski, Sun, Talbot, Vanarsdall, Vanarsdall, Wang, Wang, Wang, Warming, Wille, Yu   +87 more
core   +2 more sources