Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates [PDF]
Advanced ScienceLysozymes are well‐known for their ability to cleave bacterial peptidoglycan, but their potential to hydrolyze viral components as a form of antiviral defense remains poorly understood.
Yu Du +5 more
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The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms [PDF]
VirusesRotavirus (RV) replicates within viroplasms, membraneless electron-dense globular cytosolic inclusions with liquid–liquid phase properties. In these structures occur the virus transcription, replication, and packaging of the virus genome in newly ...
Janine Vetter +2 more
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The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication [PDF]
mBioRotavirus (RV) replication takes place in the viroplasms, cytosolic inclusions that allow the synthesis of virus genome segments and their encapsidation in the core shell, followed by the addition of the second layer of the virion.
Janine Vetter +11 more
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Rotavirus NSP2: A Master Orchestrator of Early Viral Particle Assembly [PDF]
VirusesRotaviruses (RVs) are 11-segmented, double-stranded (ds) RNA viruses and important causes of acute gastroenteritis in humans and other animal species.
Sarah L. Nichols +3 more
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Characterization of viroplasm formation during the early stages of rotavirus infection [PDF]
Virology Journal, 2010 Background During rotavirus replication cycle, electron-dense cytoplasmic inclusions named viroplasms are formed, and two non-structural proteins, NSP2 and NSP5, have been shown to localize in these membrane-free structures.
Isa Pavel +4 more
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Association of rotavirus viroplasms with microtubules through NSP2 and NSP5 [PDF]
Memorias do Instituto Oswaldo Cruz, 2006 Rotavirus replication and virus assembly take place in electrodense spherical structures known as viroplasms whose main components are the viral proteins NSP2 and NSP5.
Claudio Cabral-Romero +1 more
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Sneaking into the viral safe-houses: Implications of host components in regulating integrity and dynamics of rotaviral replication factories [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 The biology of the viral life cycle essentially includes two structural and functional entities—the viral genome and protein machinery constituting the viral arsenal and an array of host cellular components which the virus closely associates with—to ...
Pritam Chandra +4 more
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Virology Journal, 2011 Background Rice black-streaked dwarf virus (RBSDV), a member of the genus Fijivirus within the family Reoviridae, can infect several graminaceous plant species including rice, maize and wheat, and is transmitted by planthoppers.
Yu Jialin +6 more
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Type II grass carp reovirus utilizes autophagosomes for viroplasm formation and subclinical persistent infection [PDF]
Journal of VirologyGrass carp reovirus (GCRV) is the most virulent pathogen within the genus Aquareovirus, belonging to the family Spinareoviridae. GCRV is categorized into three genotypes, with type II (GCRV-II) being the predominant strain circulating in China ...
Qian Wang +9 more
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Rotavirus viroplasm fusion and perinuclear localization are dynamic processes requiring stabilized microtubules. [PDF]
PLoS ONE, 2012 Rotavirus viroplasms are cytosolic, electron-dense inclusions corresponding to the viral machinery of replication responsible for viral template transcription, dsRNA genome segments replication and assembly of new viral cores. We have previously observed
Catherine Eichwald +7 more
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