Results 121 to 130 of about 1,807 (187)

Direct visualization of the small hydrophobic protein of human respiratory syncytial virus reveals the structural basis for membrane permeability [PDF]

open access: yes, 2010
Human respiratory syncytial virus (HRSV) is the leading cause of lower respiratory tract disease in infants. The HRSV small hydrophobic (SH) protein plays an important role in HRSV pathogenesis, although its mode of action is unclear.
Atkins, Elizabeth   +10 more
core   +3 more sources

Small Ion Channel Linking Molecular Simulations and Electrophysiology [PDF]

open access: yes
Ion channels are pore-forming protein assemblies that mediate the transport of small ions across cell membranes. Otherwise, membrane bilayers would be almost impermeable to ions incapable to traverse the low dielectric constant, hydrophobic membrane core.
Pohorille, Andrzej
core   +1 more source

Coronavirus proteins as ion channels: Current and potential research [PDF]

open access: yes, 2020
Coronavirus (CoV) outbreaks have recently emerged as a global public health threat due to their exceptional zoonotic potential - a feature arising from their ability to infect a diverse range of potential hosts combined with their high capacity for ...
Hanson, Alex   +3 more
core   +1 more source

Investigations of Cell-Penetrating and Membrane-Pore Forming Peptides [PDF]

open access: yes, 2020
Cell-penetrating and membrane-pore forming peptides are a class of membrane-active peptides. They are short sequence peptides having both hydrophilic and lipophilic combinations of amino acids.
Pokhrel, Rudramani
core   +1 more source

Biological Function and Application of Picornaviral 2B Protein: A New Target for Antiviral Drug Development

open access: yesViruses, 2019
Picornaviruses are associated with acute and chronic diseases. The clinical manifestations of infections are often mild, but infections may also lead to respiratory symptoms, gastroenteritis, myocarditis, meningitis, hepatitis, and poliomyelitis, with ...
Zengbin Li   +4 more
doaj   +1 more source

Viroporin-mediated Membrane Permeabilization [PDF]

open access: yesJournal of Biological Chemistry, 2002
Aitziber Agirre   +3 more
openaire   +1 more source

Investigation of Molecular Mechanism of JC virus Viroporin Activity

open access: yesUirusu, 2015
Viroporins are small and hydrophobic viral proteins that form pores on host cell membranes, and their expression can increase the permeability of cellular membranes and the production of progeny virus particles. JC virus (JCV) is the causative agent of progressive multifocal leukoenchephalopathy (PML).
openaire   +3 more sources

Biophysical mechanisms of membrane perturbation and signal transduction produced by proteins and peptides [PDF]

open access: yes, 2015
My primary research interest is focused on the field of cellular electrical activity, ranging from the ion channels that generates it, up to the study of intracellular processes regulating it, and new generation of drugs. For this purpose, during my Ph.D.
Fasoli, Anna
core  

Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7

open access: yesDrug Design, Development and Therapy, 2018
Yasmine M Mandour,1 Ulrike Breitinger,2 Chunlong Ma,3 Jun Wang,3 Frank M Boeckler,4 Hans-Georg Breitinger,2 Darius P Zlotos1 1Department of Pharmaceutical Chemistry, German University in Cairo, 2Department of Biochemistry, The German University in Cairo,
Mandour YM   +6 more
doaj  

Viroporin Activity of SARS-CoV E Protein [PDF]

open access: yes, 2006
Liao, Ying, Tam, James P., Liu, Ding X.
openaire   +2 more sources

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