Results 101 to 110 of about 1,345 (158)
Investigation of HMA derivatives as small molecule inhibitors of viroporins
, 2023 Seasonal and pandemic viral infections continue to pose severe challenges to human health. Antivirals that can effectually complement current vaccination strategies are vital in the battle against drug-resistant pandemic viral strains.
Jalily Hasani, Pouria
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Viruses, 2019 Picornaviruses are associated with acute and chronic diseases. The clinical manifestations of infections are often mild, but infections may also lead to respiratory symptoms, gastroenteritis, myocarditis, meningitis, hepatitis, and poliomyelitis, with ...
Zengbin Li +4 more
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Investigation of Molecular Mechanism of JC virus Viroporin Activity
Uirusu, 2015 Viroporins are small and hydrophobic viral proteins that form pores on host cell membranes, and their expression can increase the permeability of cellular membranes and the production of progeny virus particles. JC virus (JCV) is the causative agent of progressive multifocal leukoenchephalopathy (PML).
openaire +3 more sources
The Rotavirus NSP4 Viroporin Domain is a Calcium-conducting Ion Channel
, 2017 Viroporins are small virus-encoded ion channel proteins. Most viroporins are monovalent selective cation channels, with few showing the ability to conduct divalent cations, like calcium (Ca2+). Nevertheless, some viroporins are known to disrupt host cell
Anne H. Delcour +4 more
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Role of SARS-CoV viroporins E, 3a and 8a in virus replication and virulence: complementation between the PBMs of E and 3a proteins [PDF]
, 2020 Trabajo presentado en el XIV Congreso Nacional de Virología, celebrado en Cádiz (España), del 11 al 14 de junio de 2017Severe acute respiratory syndrome coronavirus (SARS-CoV) causes lethal disease in humans, which is characterized by exacerbated ...
Solá Gurpegui, Isabel +12 more
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Viroporin-mediated Membrane Permeabilization [PDF]
Journal of Biological Chemistry, 2002 Aitziber Agirre +3 more
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The Ion Channels Coded by Viruses
, 2003 Pathogenicity and virulence are multifactorial traits, depending on interaction of viruses with susceptible cells and organisms. The ion channels coded by viruses, viroporins, represent only one factor taking part in the cascade of interactions between ...
Čiampor, F.
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Correction for Castaño-Rodriguez et al., "Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis". [PDF]
mBio, 2023 Castaño-Rodríguez C +14 more
europepmc +1 more source