Results 81 to 90 of about 1,345 (158)

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Impact of Vesicular Stomatitis Virus M Proteins on Different Cellular Functions. [PDF]

open access: yesPLoS ONE, 2015
Three different matrix (M) proteins termed M1, M2 and M3 have been described in cells infected with vesicular stomatitis virus (VSV). Individual expression of VSV M proteins induces an evident cytopathic effect including cell rounding and detachment, in ...
Natalia Redondo   +3 more
doaj   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

open access: yesMedicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi   +9 more
wiley   +1 more source

Transcription Kinetics in the Coronavirus Life Cycle

open access: yesWIREs RNA, Volume 16, Issue 1, January/February 2025.
The steps involved in a Coronavirus infection are interconnected and exhibit complex kinetics, with some processes depending on each other, while others occur independently. Understanding the basic kinetics of major processes like translation, transcription, and virion assembly in the Coronavirus life cycle adds temporal resolution to the classical ...
Katarzyna Grelewska‐Nowotko   +2 more
wiley   +1 more source

Plum pox virus: An overview of the potyvirus behind sharka, a harmful stone fruit disease

open access: yesAnnals of Applied Biology, Volume 186, Issue 1, Page 49-75, January 2025.
Plum pox virus is a member of the genus Potyvirus in the family Potyviridae. The significance of this virus is underscored by its large strain diversity, wide host range, broad geographical distribution and the great socio‐economic impact of sharka, the disease it causes. Abstract The study of Potyvirus plumpoxi (plum pox virus, PPV) has a long history,
Juan Antonio García   +5 more
wiley   +1 more source

The Interplay Between Viral Infection and Cell Death: A Ping‐Pong Effect

open access: yesAdvances in Virology, Volume 2025, Issue 1, 2025.
Programmed cell death (PCD) is a well‐studied cellular mechanism that plays a critical role in immune responses, developmental processes, and the maintenance of tissue homeostasis. However, viruses have developed diverse strategies to bypass or manipulate the host apoptotic machinery to enhance their replication and survival.
Alireza Nourazarian   +5 more
wiley   +1 more source

Mouse polyomavirus infection induces lamin reorganisation

open access: yesThe FEBS Journal, Volume 291, Issue 23, Page 5133-5155, December 2024.
Here, we investigated the roles of lamins as important nuclear proteins in the replication cycle of the mouse polyomavirus. We detected accumulation of the major capsid protein VP1 under the nuclear lamina, defects in nuclear lamina staining and different lamin A/C phosphorylation patterns following viral infection.
Kateřina Bruštíková   +5 more
wiley   +1 more source

The Feline calicivirus Leader of the Capsid (LC) Protein Contains a Putative Transmembrane Domain, Binds to the Cytoplasmic Membrane, and Exogenously Permeates Cells

open access: yesViruses
Feline calicivirus (FCV), an important model for studying the biology of the Caliciviridae family, encodes the leader of the capsid (LC) protein, a viral factor known to induce apoptosis when expressed in a virus-free system.
Yoatzin Peñaflor-Téllez   +7 more
doaj   +1 more source

Emerging Therapeutics in the Fight Against EV‐D68: A Review of Current Strategies

open access: yesInfluenza and Other Respiratory Viruses, Volume 18, Issue 12, December 2024.
ABSTRACT Enterovirus‐D68 (EV‐D68) was first identified in 1962 in pediatric patients with acute respiratory conditions in California, USA (US). From the 1970s to 2005, EV‐D68 was underestimated due to limited data and serotyping methods. In 2014, the United States experienced outbreaks of acute flaccid myelitis (AFM) in children EV‐D68 positive.
Nida Kalam   +1 more
wiley   +1 more source

Benchmarking Molecular Dynamics Simulations of Influenza A M2 Viroporin Complexes in Standard Lipid Bilayers

open access: yes, 2021
Data sharing and availability section for "Benchmarking Molecular Dynamics Simulations for Viroporins: the case of Influenza A M2", Kolokouris, Dimitrios; Kalenderolgou, Iris; Lagarias, Panagiotis; Kolocouris ...
Kolocouris, Antonios   +2 more
core   +1 more source

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