Results 61 to 70 of about 1,355 (133)
Viroporins from RNA viruses induce caspase-dependent apoptosis
, 2008 The virus‐encoded viroporins are known to modify membrane permeability and play an essential role in virus budding. Here, a comparative analysis of the membrane permeabilization capacity of a number of viroporins was performed in baby hamster kidney ...
Castelló, Alfredo +2 more
core +1 more source
Structural and Functional Properties of the Hepatitis C Virus p7 Viroporin
Viruses, 2015 The high prevalence of hepatitis C virus (HCV) infection in the human population has triggered intensive research efforts that have led to the development of curative antiviral therapy.
Vanesa Madan, Ralf Bartenschlager
doaj +1 more source
The Antiviral Activity of Polyphenols
Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard +5 more
wiley +1 more source
Unravelling the immunomodulatory effects of viral ion channels, towards the treatment of disease
, 2022 The current COVID-19 pandemic has highlighted the need for the research community to develop a better understanding of viruses, in particular their modes of infection and replicative lifecycles, to aid in the development of novel vaccines and much needed
Siobhan Gargan (11907946) +1 more
core +3 more sources
Impact of Vesicular Stomatitis Virus M Proteins on Different Cellular Functions. [PDF]
PLoS ONE, 2015 Three different matrix (M) proteins termed M1, M2 and M3 have been described in cells infected with vesicular stomatitis virus (VSV). Individual expression of VSV M proteins induces an evident cytopathic effect including cell rounding and detachment, in ...
Natalia Redondo +3 more
doaj +1 more source
A metastasis‐associated pannexin‐1 mutant (Panx11‐89) forms a minimalist ATP release channel
The FEBS Journal, Volume 292, Issue 13, Page 3378-3396, July 2025.A truncation mutant of Panx1 (Panx11‐89), enriched in metastatic breast cancer cells, is capable of forming a large ATP‐permeable membrane channel despite containing only 20% of the amino‐terminal amino acids of the wild‐type channel protein (wtPanx1). However, cells expressing Panx11‐89 alone die, whereas co‐expression of wtPanx1 is protective.
Junjie Wang +5 more
wiley +1 more source
VirusesFeline calicivirus (FCV), an important model for studying the biology of the Caliciviridae family, encodes the leader of the capsid (LC) protein, a viral factor known to induce apoptosis when expressed in a virus-free system.
Yoatzin Peñaflor-Téllez +7 more
doaj +1 more source
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi +9 more
wiley +1 more source
Transcription Kinetics in the Coronavirus Life Cycle
WIREs RNA, Volume 16, Issue 1, January/February 2025.The steps involved in a Coronavirus infection are interconnected and exhibit complex kinetics, with some processes depending on each other, while others occur independently. Understanding the basic kinetics of major processes like translation, transcription, and virion assembly in the Coronavirus life cycle adds temporal resolution to the classical ...
Katarzyna Grelewska‐Nowotko +2 more
wiley +1 more source
Plum pox virus: An overview of the potyvirus behind sharka, a harmful stone fruit disease
Annals of Applied Biology, Volume 186, Issue 1, Page 49-75, January 2025.Plum pox virus is a member of the genus Potyvirus in the family Potyviridae. The significance of this virus is underscored by its large strain diversity, wide host range, broad geographical distribution and the great socio‐economic impact of sharka, the disease it causes. Abstract The study of Potyvirus plumpoxi (plum pox virus, PPV) has a long history,
Juan Antonio García +5 more
wiley +1 more source