Results 91 to 100 of about 1,807 (187)
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi +9 more
wiley +1 more source
Targeting Viral Ion Channels: A Promising Strategy to Curb SARS-CoV-2
Pharmaceuticals, 2022 SARS-CoV-2 is the etiological agent COVID-19, one of the most impactful health crises afflicting humanity in recent decades. While research advances have yielded several treatment and prevention options, the pandemic is slow to abate, necessitating an ...
Anamika Singh, Isaiah T. Arkin
doaj +1 more source
The Encephalomyocarditis Virus [PDF]
, 2012 The encephalomyocarditis virus (EMCV) is a small non-enveloped single-strand RNA virus, the causative agent of not only myocarditis and encephalitis, but also neurological diseases, reproductive disorders and diabetes in many mammalian species.
Bakkali-Kassimi, Labib, Carocci, Margot
core +2 more sources
Transcription Kinetics in the Coronavirus Life Cycle
WIREs RNA, Volume 16, Issue 1, January/February 2025.The steps involved in a Coronavirus infection are interconnected and exhibit complex kinetics, with some processes depending on each other, while others occur independently. Understanding the basic kinetics of major processes like translation, transcription, and virion assembly in the Coronavirus life cycle adds temporal resolution to the classical ...
Katarzyna Grelewska‐Nowotko +2 more
wiley +1 more source
Beyond Channel Activity: Protein-Protein Interactions Involving Viroporins [PDF]
, 2018 Viroporins are short polypeptides encoded by viruses. These small membrane proteins assemble into oligomers that can permeabilize cellular lipid bilayers, disrupting the physiology of the host to the advantage of the virus. Consequently, efforts during the last few decades have been focused towards the discovery of viroporin channel inhibitors, but in ...
To, Janet, Torres, Jaume
openaire +2 more sources
Plum pox virus: An overview of the potyvirus behind sharka, a harmful stone fruit disease
Annals of Applied Biology, Volume 186, Issue 1, Page 49-75, January 2025.Plum pox virus is a member of the genus Potyvirus in the family Potyviridae. The significance of this virus is underscored by its large strain diversity, wide host range, broad geographical distribution and the great socio‐economic impact of sharka, the disease it causes. Abstract The study of Potyvirus plumpoxi (plum pox virus, PPV) has a long history,
Juan Antonio García +5 more
wiley +1 more source
Single-molecule conformational dynamics of viroporin ion channels regulated by lipid-protein interactions [PDF]
, 2020 Classic swine fever is a highly contagious and often fatal viral disease that is caused by the classical swine fever virus (CSFV). Protein p7 of CFSV is a prototype of viroporin, a family of small, highly hydrophobic proteins postulated to modulate virus-
Alcaraz, Antonio +4 more
core +1 more source
The Interplay Between Viral Infection and Cell Death: A Ping‐Pong Effect
Advances in Virology, Volume 2025, Issue 1, 2025.Programmed cell death (PCD) is a well‐studied cellular mechanism that plays a critical role in immune responses, developmental processes, and the maintenance of tissue homeostasis. However, viruses have developed diverse strategies to bypass or manipulate the host apoptotic machinery to enhance their replication and survival.
Alireza Nourazarian +5 more
wiley +1 more source
Planar Lipid Bilayer Analysis of Candidate Rotavirus Antivirals [PDF]
, 2023 Case rates of rotavirus, the leading viral cause of severe acute diarrhea in children under the age of 5, have been steadily declining in countries that have had access to effective mitigation strategies.
Tamkin, Emily H
core +1 more source
Mouse polyomavirus infection induces lamin reorganisation
The FEBS Journal, Volume 291, Issue 23, Page 5133-5155, December 2024.Here, we investigated the roles of lamins as important nuclear proteins in the replication cycle of the mouse polyomavirus. We detected accumulation of the major capsid protein VP1 under the nuclear lamina, defects in nuclear lamina staining and different lamin A/C phosphorylation patterns following viral infection.
Kateřina Bruštíková +5 more
wiley +1 more source