Results 1 to 10 of about 13,136,107 (398)

Do Bacterial “Virulence Factors” Always Increase Virulence? A Meta-analysis of Pyoverdine Production inPseudomonas aeruginosa as a Test Case [PDF]

Frontiers in Microbiology, 2016
Bacterial traits that contribute to disease are termed ‘virulence factors’ and there is much interest in therapeutic approaches that disrupt such traits.
Elisa Granato, Freya Harrison, Rolf Kümmerli, Adin Ross-Gillespie, Adin Ross-Gillespie   +4 more
doaj   +4 more sources

NSs: the multifaceted bunyavirus virulence factor [PDF]

npj Viruses
Bunyaviricetes represents a diverse class of RNA viruses, including hundreds of species distributed worldwide that threaten human and animal health. This Perspective briefly overviews bunyaviruses infecting humans and other mammals, focusing on their key
Maëva Duboeuf, Anne-Flore Legrand, Pierre-Yves Lozach, Carine Maisse   +3 more
doaj   +2 more sources

Identification of Streptococcus suis putative zoonotic virulence factors: A systematic review and genomic meta-analysis

Virulence, 2021
Streptococcus suis is an emerging zoonotic pathogen. Over 100 putative virulence factors have been described, but it is unclear to what extent these virulence factors could contribute to zoonotic potential of S. suis. We identified all S.
Thomas J. Roodsant, Boas C.L. Van Der Putten, Sara M. Tamminga, Constance Schultsz, Kees C.H. Van Der Ark   +4 more
doaj   +2 more sources

Vibrio cholerae ToxR Downregulates Virulence Factor Production in Response to Cyclo(Phe-Pro)

mBio, 2013
Vibrio cholerae is an aquatic organism that causes the severe acute diarrheal disease cholera. The ability of V. cholerae to cause disease is dependent upon the production of two critical virulence determinants, cholera toxin (CT) and the toxin ...
X. Renee Bina, Dawn L. Taylor, Amit Vikram, Vanessa M. Ante, James E. Bina   +4 more
doaj   +2 more sources

Advancing virulence factor prediction using protein language models [PDF]

BMC Biology
Background Bacterial infections rank as the second leading cause of death globally, with virulence factors (VFs) being crucial to their pathogenicity.
Yitong Liu, Xin Cao, Jiani Li, Tao Li, Juanjuan Li, Xiang Ma, Xue Chi, Yanqiong Tang, Zhu Liu, Hong Li   +9 more
doaj   +2 more sources

Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor [PDF]

Journal of Biological Chemistry, 2011
Metacaspases are caspase family cysteine peptidases found in plants, fungi, and protozoa but not mammals. Trypanosoma brucei is unusual in having five metacaspases (MCA1-MCA5), of which MCA1 and MCA4 have active site substitutions, making them possible ...
Absalon, Alsford, Ambit, Bangs, Bastin, Belenghi, Birkett, Bozhkov, Broadhead, Burleigh, Coll, Emmer, Emmer, Emmer, Field, Geiger, Grébaut, Helms, Kelly, LaCount, Lee, Lee, Liu, Madeo, Mills, Morty, Moss, Mottram, Munday, Pils, Pop, Silverman, Sundström, Szallies, Sárkány, Tsiatsiani, Uren, Vercammen, Watanabe, Webb, Wirtz, Yu, Zalila, Zettl   +43 more
core   +4 more sources

The Epistemology of Bacterial Virulence Factor Characterization [PDF]

Microorganisms
The field of microbial pathogenesis seeks to identify the agents and mechanisms responsible for disease causation. Since Robert Koch introduced postulates that were used to guide the characterization of microbial pathogens, technological advances have ...
Matthew Jackson, Susan Vineberg, Kevin R. Theis   +2 more
doaj   +2 more sources

Microbial Virulence Factors [PDF]

International Journal of Molecular Sciences, 2020
Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease [...]
openaire   +4 more sources

Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila.

PLoS ONE, 2023
Quorum sensing is a communication strategy that bacteria use to collectively alter gene expression in response to cell density. Pathogens use quorum sensing systems to control activities vital to infection, such as the production of virulence factors and
Katie A Acken, Bo Li
doaj   +1 more source

Concept about the Virulence Factor of Legionella

Microorganisms, 2022
Pathogenic species of Legionella can infect human alveolar macrophages through Legionella-containing aerosols to cause a disease called Legionellosis, which has two forms: a flu-like Pontiac fever and severe pneumonia named Legionnaires’ disease (LD ...
Jin-Lei Yang, Danyang Li, Xiao-Yong Zhan
doaj   +1 more source