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NSs: the multifaceted bunyavirus virulence factor [PDF]
npj VirusesBunyaviricetes represents a diverse class of RNA viruses, including hundreds of species distributed worldwide that threaten human and animal health. This Perspective briefly overviews bunyaviruses infecting humans and other mammals, focusing on their key
Maëva Duboeuf +3 more
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Advancing virulence factor prediction using protein language models [PDF]
BMC BiologyBackground Bacterial infections rank as the second leading cause of death globally, with virulence factors (VFs) being crucial to their pathogenicity.
Yitong Liu +9 more
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Targeting anti-virulence factor strategies of bacterial pathogens [PDF]
Biosafety and HealthAntibiotic-resistant bacterial pathogens pose substantial biosafety and health hazards, leading to millions of deaths each year. The evolution of bacterial virulence factors is mainly propelled by horizontal gene transfer (HGT).
Jiashu Li, Tianyuan Jia, Liang Yang
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Microbial Virulence Factors [PDF]
International Journal of Molecular Sciences, 2020 Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease [...]
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Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila.
PLoS ONE, 2023 Quorum sensing is a communication strategy that bacteria use to collectively alter gene expression in response to cell density. Pathogens use quorum sensing systems to control activities vital to infection, such as the production of virulence factors and
Katie A Acken, Bo Li
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Concept about the Virulence Factor of Legionella
Microorganisms, 2022 Pathogenic species of Legionella can infect human alveolar macrophages through Legionella-containing aerosols to cause a disease called Legionellosis, which has two forms: a flu-like Pontiac fever and severe pneumonia named Legionnaires’ disease (LD ...
Jin-Lei Yang, Danyang Li, Xiao-Yong Zhan
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Clonal Origin, Virulence Factors, and Virulence [PDF]
Infection and Immunity, 2000 The recent report from Picard et al. regarding extraintestinal Escherichia coli infections provides new insights into the relationships between clonal origin, virulence factor repertoire, and virulence (1). That clonal origin was only secondarily associated with virulence in this study was suggested by the finding that although mouse lethality was more
J R, Johnson, M, Kuskowski
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The Vibrio cholerae RND efflux systems impact virulence factor production and adaptive responses via periplasmic sensor proteins. [PDF]
PLoS Pathogens, 2018 Resistance-nodulation-division (RND) efflux systems are ubiquitous transporters in Gram-negative bacteria that are essential for antibiotic resistance. The RND efflux systems also contribute to diverse phenotypes independent of antimicrobial resistance ...
X Renee Bina +5 more
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Virulence, 2021 Streptococcus suis is an emerging zoonotic pathogen. Over 100 putative virulence factors have been described, but it is unclear to what extent these virulence factors could contribute to zoonotic potential of S. suis. We identified all S.
Thomas J. Roodsant +4 more
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The splicing factor SR2 is an important virulence factor of Toxoplasma gondii
Frontiers in Microbiology, 2023 Serine/arginine-rich (SR) proteins are key factors with important roles in constitutive and alternative splicing (AS) of pre-mRNAs. However, the role of SR splicing factors in the pathogenicity of T. gondii remains largely unexplored.
Xiao-Jing Wu +10 more
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