Results 31 to 40 of about 13,136,107 (398)
Phytohormone-mediated interkingdom signaling shapes the outcome of rice-Xanthomonas oryzae pv. oryzae interactions [PDF]
, 2015 Background: Small-molecule hormones are well known to play key roles in the plant immune signaling network that is activated upon pathogen perception. In contrast, little is known about whether phytohormones also directly influence microbial virulence ...
De Vleesschauwer, David +7 more
core +2 more sources
mBio, 2017 The SaeRS two-component system is a master activator of virulence factor transcription in Staphylococcus aureus, but the cellular factors that control its activity are unknown.
M. Ericson +3 more
semanticscholar +1 more source
Pathogenicity and virulence of Clostridioides difficile
Virulence, 2022 Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhea, and is responsible for a spectrum of diseases characterized by high levels of recurrence, morbidity, and mortality.
Jessica E. Buddle, Robert P. Fagan
semanticscholar +1 more source
Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
mBio, 2023 Virulence effectors secreted by Mycobacterium tuberculosis (Mtb) help subvert host immune mechanisms and, therefore, are critical for establishing infection and pathogenesis. However, knowledge in terms of signaling mechanisms that modulate the secretion
Basanti Malakar +9 more
doaj +1 more source
Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa
Toxins, 2016 Pyocyanin has recently emerged as an important virulence factor produced by Pseudomonas aeruginosa. The redox-active tricyclic zwitterion has been shown to have a number of potential effects on various organ systems in vitro, including the respiratory ...
Susan Hall +10 more
semanticscholar +1 more source
Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA
Scientific Reports, 2016 CagA, encoded by cytotoxin-associated gene A (cagA), is a major virulence factor of Helicobacter pylori, a gastric pathogen involved in the development of upper gastrointestinal diseases. Infection with cagA-positive H. pylori may also be associated with
A. Shimoda +8 more
semanticscholar +1 more source
Iranian Journal of Microbiology, 2023 Background and Objectives: Extraintestinal pathogenic Escherichia coli (ExPEC) is a recently recognized and highly diverse pathotype of E. coli. Its significance as a pathogen has increased due to the emergence of hypervirulent and multidrug-resistant ...
Alfredo Montes-Robledo +2 more
doaj +1 more source
Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice [PDF]
, 2016 Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain of Schmallenberg virus (SBV) serially passaged in tissue culture ...
Aislynn Taggart +13 more
core +1 more source
Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors
iScience, 2020 Summary: Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to ...
Diego López León +7 more
doaj +1 more source
Breaking the bad: Bacillus blocks fungal virulence factors
Microbial Cell, 2017 Fungal pathogens rely on the production of specific virulence factors during infection. Inhibiting such factors generally results in reduced fungal pathogenicity.
François L. Mayer, James W. Kronstad
doaj +1 more source