Results 191 to 200 of about 13,827 (215)

Mutations in the linker region of Bvgs abolish response to environmental signals for the regulation of the virulence factors in bordetella pertussis

Gene, 1994
Expression of virulence factors of Bordetella pertussis is coordinately regulated by the products of the bvg locus, which codes for a sensory protein (BvgS) and a positive regulator of transcription (BvgA), a pair in the family of bacterial 'two-component' regulators. Transcription of the bvg-regulated promoters is repressed by modulating environmental
Manetti R., Arico B., Rappuoli R., Scarlato V.   +3 more
openaire   +3 more sources

Regulatory factors of Bordetella pertussis affecting virulence gene expression.

Journal of molecular microbiology and biotechnology, 2002
Most pathogenic bacteria encounter changing growth conditions during their infectious cycle and, accordingly, have to modulate gene expression to enable the efficient colonization of different environments outside or within their host organisms. In Bordetella pertussis the transcription of most virulence factors including several toxins and adhesins is
Jochen, König, Andreas, Bock, Anne-Laure, Perraud, Thilo M, Fuchs, Dagmar, Beier, Roy, Gross   +5 more
openaire   +1 more source

Bacterial growth and virulence factors production by different Bordetella pertussis strains.

Acta microbiologica Polonica, 1997
The aim of this study was to compare bacteria growth and pertussis antigens (pertussis toxin-PT, filamentous haemagglutinin-FHA and endotoxin-LPS) production by 11 Bordetella pertussis strains. A synthetic Stainer-Scholte culture medium supplemented with (2,6-0-dimethyl) beta-cyclodextrin (heptakis) or methylcellulose (for greater PT and FHA production)
I, Letowska, M, Chodorowska, E, Kaczurba, D, Kuklińska, S, Tyski   +4 more
openaire   +1 more source

Bordetella adenylate cyclase: a genus specific protective antigen and virulence factor.

Developments in biological standardization, 1986
Most of the adenylate cyclase (AC) present in Bordetella species is localized in the outer membrane, partly exposed to the cell surface. An isolation procedure to obtain the cell-bound enzyme was applied to Bordetella bronchiseptica, Bordetella pertussis and Bordetella parapertussis. Passive transfer of B. bronchiseptica anti-AC antibody, either in the
P, Novotny, A P, Chubb, K, Cownley, J A, Montaraz, J E, Beesley   +4 more
openaire   +1 more source

Leveraging Bordetella heterogeneity to identify novel virulence factors

Pertussis (aka whooping cough) is a serious, re-emerging public health concern despite available vaccines. The acellular vaccine against Bordetella pertussis, used in the U.S. since the 1990s, prevents serious disease, but not colonization or transmission, resulting in a larger reservoir from which infants, who are most vulnerable, can be infected. New
openaire   +1 more source

Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence

Frontiers in Cellular and Infection Microbiology, 2021
Laurence Don Wai Luu, Ruiting Lan
exaly  

Bordetella PlrSR regulatory system controls BvgAS activity and virulence in the lower respiratory tract

Proceedings of the National Academy of Sciences of the United States of America, 2017
Andrew Perault, Qing Chen, Peggy A Cotter   +2 more
exaly  

Differential regulation of type III secretion and virulence genes inBordetella pertussisandBordetella bronchisepticaby a secreted anti-σ factor

Proceedings of the National Academy of Sciences of the United States of America, 2016
Bhumika Shokeen, Giovanni Coppola, Virginia L Miller   +2 more
exaly  

Allele frequencies of Bordetella pertussis virulence-associated genes identified from pediatric patients with severe respiratory infections

Journal of Infection and Chemotherapy, 2020
Kensuke Shoji, Akira Ishiguro, Isao Miyairi   +2 more
exaly  

Development of macrolide resistance in Bordetella bronchiseptica is associated with the loss of virulence

Journal of Antimicrobial Chemotherapy, 2018
Kalyan K Dewan, Amanda L Skarlupka, Israel Rivera   +2 more
exaly