Bioinformatics approaches for unveiling virus-host interactions [PDF]
The coronavirus disease-2019 (COVID-19) pandemic has elucidated major limitations in the capacity of medical and research institutions to appropriately manage emerging infectious diseases.
Hitoshi Iuchi +8 more
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CRISPR-resolved virus-host interactions in a municipal landfill include non-specific viruses, hyper-targeted viral populations, and interviral conflicts [PDF]
Viruses are the most abundant microbial guild on the planet, impacting microbial community structure and ecosystem services. Viruses are specifically understudied in engineered environments, including examinations of their host interactions.
Nikhil A. George, Laura A. Hug
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The Dengue virus (DENV) and Chikungunya virus (CHIKV) are the arboviruses that pose a threat to global public health. Coinfection and antibody-dependent enhancement are major areas of concern during DENV and CHIKV infections, which can alter the clinical
Debjani Taraphdar +9 more
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Viral Hijack of Filamentous Surface Structures in Archaea and Bacteria
The bacterial and archaeal cell surface is decorated with filamentous surface structures that are used for different functions, such as motility, DNA exchange and biofilm formation. Viruses hijack these structures and use them to ride to the cell surface
Colin Tittes +2 more
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Epstein–Barr virus–host cell interactions: an epigenetic dialog? [PDF]
Here, we wish to highlight the genetic exchange and epigenetic interactions between Epstein-Barr virus (EBV) and its host. EBV is associated with diverse lymphoid and epithelial malignancies. Their molecular pathogenesis is accompanied by epigenetic alterations which are distinct for each of them.
Niller, Hans H. +2 more
openaire +2 more sources
Archaeal Host Cell Recognition and Viral Binding of HFTV1 to Its Haloferax Host
Viruses are highly abundant and the main predator of microorganisms. Microorganisms of each domain of life are infected by dedicated viruses. Viruses infecting archaea are genomically and structurally highly diverse.
Sabine Schwarzer +3 more
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Cellular and Genomic Properties of Haloferax gibbonsii LR2-5, the Host of Euryarchaeal Virus HFTV1
Hypersaline environments are the source of many viruses infecting different species of halophilic euryarchaea. Information on infection mechanisms of archaeal viruses is scarce, due to the lack of genetically accessible virus–host models. Recently, a new
Colin Tittes +7 more
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Structural insights into the mechanism of archaellar rotational switching
Signal transduction via phosphorylated CheY is conserved in bacteria and archaea. In this study, the authors employ structural biochemistry combined with cell biology to delineate the mechanism of CheY recognition by the adaptor protein CheF.
Florian Altegoer +10 more
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Growth Phase Dependent Cell Shape of Haloarcula
Several haloarchaea are reported to be pleomorphic, while others exhibit remarkable shapes, such as squares. Recently, Haloferax volcanii was found to alter its morphology during growth.
Sabine Schwarzer +3 more
doaj +1 more source
Decreased MIP-3α Production from Antigen-Activated PBMCs in Symptomatic HIV-Infected Subjects
CD4+ CCR6+ T cells are highly susceptible to HIV infection, and a high cytokine producing CCR6+ T cell subset is selectively lost during HIV infection. The CCR6 chemokine MIP-3α (CCL20) is produced at sites of infection in SIV animal models. Recently, we
Fuchun Zhang +4 more
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