Results 21 to 30 of about 253,847 (119)

Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function

Cell Reports, 2016
Sister chromatid cohesion is a fundamental prerequisite to faithful genome segregation. Cohesion is precisely regulated by accessory factors that modulate the stability with which the cohesin complex embraces chromosomes.
Kyle W. Muir, Marc Kschonsak, Yan Li, Jutta Metz, Christian H. Haering, Daniel Panne   +5 more
doaj   +1 more source

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

EMBO Molecular Medicine, 2017
Toxoplasma gondii is an important food and waterborne pathogen causing toxoplasmosis, a potentially severe disease in immunocompromised or congenitally infected humans.
Andrés Palencia, Alexandre Bougdour, Marie‐Pierre Brenier‐Pinchart, Bastien Touquet, Rose‐Laurence Bertini, Cristina Sensi, Gabrielle Gay, Julien Vollaire, Véronique Josserand, Eric Easom, Yvonne R Freund, Hervé Pelloux, Philip J Rosenthal, Stephen Cusack, Mohamed‐Ali Hakimi   +14 more
doaj   +1 more source

Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells

Journal of Virology
Abundance of essential components of double-stranded RNA (dsRNA) recognition and the subsequent interferon (IFN) response vary widely between primary human hepatocytes (PHHs) and commonly used cell culture models based on derivatives of Huh7 cells ...
Andreas Betz, Hao-En Huang, Zuguang Gu, Ombretta Colasanti, Teng-Feng Li, Jasper Hesebeck-Brinckmann, Nadine Gillich, Gnimah Eva Gnouamozi, Matthias Schlesner, Florian W. R. Vondran, Stephan Urban, Ralf Bartenschlager, Marco Binder, Volker Lohmann   +13 more
doaj   +1 more source

Identification of a culturable fungal species and endosymbiotic bacteria in saliva of Aedes aegypti and Culex pipiens and their impact on arbovirus infection in vitro

Parasites & Vectors
Background Mosquito saliva plays a key role in arbovirus transmission and pathogenesis. It was shown that saliva contains several molecules that are essential for blood feeding.
Lanjiao Wang, Laure Remue, Nikki Adriaens, Alina Soto, Sam Verwimp, Joyce van Bree, Katrien Trappeniers, Leen Delang   +7 more
doaj   +1 more source

Is Culex modestus a New Usutu virus vector?

Parasites & Vectors
Usutu virus is an emerging pathogen transmitted by mosquitoes. Culex modestus mosquitoes are widespread in Europe, but their role in disease transmission is poorly understood.
Alina Soto, Lotte Wauters, Leen Delang
doaj   +1 more source

Rapid surge of reassortant A(H1N1) influenza viruses in Danish swine and their zoonotic potential

Emerging Microbes and Infections
In 2018, a single detection of a novel reassortant swine influenza A virus (swIAV) was made in Denmark. The hemagglutinin (HA) of the virus was from the H1N1 pandemic 2009 (H1N1pdm09) lineage and the neuraminidase (NA) from the H1N1 Eurasian avian-like ...
Pia Ryt-Hansen, Sophie George, Charlotte Kristiane Hjulsager, Ramona Trebbien, Jesper Schak Krog, Marta Maria Ciucani, Sine Nygaard Langerhuus, Jennifer DeBeauchamp, Jeri Carol Crumpton, Taylor Hibler, Richard J. Webby, Lars Erik Larsen   +11 more
doaj   +1 more source

Oxidative stress biomarkers are associated with visible clinical signs of a disease in frigatebird nestlings

Scientific Reports, 2017
Infectious diseases are one of the most common threats for both domestic and wild animals, but little is known about the effects on the physiological condition and survival of wild animals.
Manrico Sebastiano, Marcel Eens, Hamada Abd Elgawad, Benoît de Thoisy, Vincent Lacoste, Kévin Pineau, Han Asard, Olivier Chastel, David Costantini   +8 more
doaj   +1 more source

Detection of Hepatitis C Virus Infection from Patient Sera in Cell Culture Using Semi-Automated Image Analysis

Viruses
The study of hepatitis C virus (HCV) replication in cell culture is mainly based on cloned viral isolates requiring adaptation for efficient replication in Huh7 hepatoma cells.
Noemi Schäfer, Paul Rothhaar, Christian Heuss, Christoph Neumann-Haefelin, Robert Thimme, Julia Dietz, Christoph Sarrazin, Paul Schnitzler, Uta Merle, Sofía Pérez-del-Pulgar, Vibor Laketa, Volker Lohmann   +11 more
doaj   +1 more source

Antibody-Dependent Dengue Virus Entry Modulates Cell Intrinsic Responses for Enhanced Infection

mSphere, 2019
Dengue is caused by infection with any one of four dengue viruses (DENV); the risk of severe disease appears to be enhanced by the cross-reactive or subneutralizing levels of antibody from a prior DENV infection.
Candice Y. Y. Chan, John Zhong Heng Low, Esther Shuyi Gan, Eugenia Ziying Ong, Summer Li-Xin Zhang, Hwee Cheng Tan, Xiaoran Chai, Sujoy Ghosh, Eng Eong Ooi, Kuan Rong Chan   +9 more
doaj   +1 more source

Citrus tristeza virus-host interactions

Frontiers in Microbiology, 2013
Citrus tristeza virus (CTV) is a phloem-limited virus whose natural host range is restricted to citrus and related species. Although the virus has killed millions of trees, almost destroying whole industries, and continually limits production in many ...
William O. Dawson, Stephen M. Garnsey, Satyanarayana eTatineni, Svetlana Y Folimonova, Scott J Harper, S eGowda   +5 more
doaj   +1 more source